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6 Cards in this Set
- Front
- Back
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ethosuximide
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1. first line absence seizures
2. may exacerbate partial and tonic clonic seizures 3. AE: psychotic behavior, blood dyscrasias, HA, anorexia, hiccups, SLE-like syndrome, parkinson-like symptoms, photophobia 4. Moa: reduce Ca currents in thalamus (T currents) |
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gabapentin
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1. adjunct/monotherapy for partial seizures
2. can exacerbate myoclonic and absence seizures 3. AE: weight gain, ankle edema, irritability, behavior in children, movement d/o 4. MoA: inhibiton Ca channel w/alpha2delta1 unit 5. mostly used diabetic neuropathy |
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pregabalin
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1. adjucnt partial
2. no effect absence, myoclonic, or tonic clonic 3. MoA: same gabapentin but more potent 4. also used fibromyalgia (neuropathic px) |
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Levetiracetam
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1. adjunct in adults w/partial seizures
2. C/I renal dysfunction 3. AE: asthenia, infection, behavioral in children 4. Moa: binding affinity to synaptic vesicle protein 2a, blocks Ca channel Na currents |
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magnesium
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use for Mg deficient seizures
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paraldehyde
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use for alcohol withdrawal seizures, delirium tremens
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