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21 Cards in this Set

  • Front
  • Back
sacchromycus cerevisial
yeast used to make beer/bread/alcohol
What are the 2 types of alveolar cells?
type 1-squamous epithelial cells
allow gas diffusion

type 2-cuboidal cells
produce surfactant, which allows for repeated expansion and prevents collapse of air sacs
What is the main pulmonary surfactant?
dipalmitoyl phosphatidyl choline

(2 tails are made of palmitic acid)
What are the main respiratory muscles?
diaphragm

rectus abdominus

external/internal intercostals
dust cells
most numerous of all cells in the lung

wander the lumens of the alveoli and phagocytize dust particles
What are the forces in glomerular filtration?
+60 blood hydrostatic pressure (BHP)
-32 colloid osmotic pressure (COP)
-18 capsular pressure (CP)
------------------------------

10 mmHg net filtration pressure
What are some of the functions of the liver?
-detoxification

-immune clearance

-role in regulation of blood volume, blood pressure (secretes angiotensinogen)

-secretes hepcidin (iron absorption)

-secretes EPO

-secretes complement proteins

-vitamin D synthesis

-secretes IGF-1 in response to GF

-gluconeogenesis (makes glucose out of proteins)
What are the 10 steps of glycolysis?
glucose

glucose 6

fructose 6

fructose 1,6 bisphosphate

(2) glyceraldehyde (and dihydroxy acetone phosphate..)

(2) 1,3 BPG

(2) 3 phosphoglycerate

(2) 2 phosphoglycerate

(2) phophoenol-pyruvate

(2) pyruvate
What is the TOTAL and NET ATP production during glycolysis?
total: 4 ATPs

-2 ATPs used
-----------------------------------

net: 2 ATPs
Where does glycolysis take place in the cell?
the cytosol
What does pyruvate dehydrogenase do?
catalyzes 3 reactions:

-dehydrogenation

-incorporation of coenzyme A

-decarboxylation
Where do the intermediate step AND the Krebs cycle occur?
the inner compartment of the mitochondria
What are the 8 steps of the Krebs cycle?
citric acid (6-c)

isocitrate (6-c)
[NAD => NADH]

alpha keto-glutarate (5-c)
[NAD => NADH]
(alpha keto glutarate dehydrogenase complex converts this into..

succinyl coA (4-c)

[GDP => GTP]


succinate (4-c)
[FAD => FADH]

fumerate (4-c)


malate (4-c)
[NAD => NADH]

oxaloacetate (4-c)
why do we need oxygen in terms of the electron transport chain?
oxygen acts as a final acceptor of electrons in ETC of mitochondria
PMF
proton motive force

pumping protons across a membrane to create a proton-motive force that can drive synthesis of another type of molecule
monosomy
lack of a chromosome
trisomy
presence of an extra chromosome
triple X syndrome
nondisjunction must occur first, meaning a pair of chromosomes fail to separate

XX receives an X from sperm, result is XXX zygote

female will be infertile and may have intellectual impairment
Klinefelter syndrome
XX receives a Y from male, resulting in XXY

sterile males; underdeveloped testes, sparse hair, and enlarged breasts
Turner syndrome
XO zygote (O means represents the absence of one sex chromosome)

ovaries are absent, girl will be sterile, and will have short stature
Down syndrome
trisomy on chromosome 21