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7 Cards in this Set
- Front
- Back
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Pneumonia |
Infection + Inflammation deep into respiratory tract branches - alveoli |
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Innate immune defences against Pneumonia |
Mucociliary escalator Alveolar macrophages Polymorphonuclear Leucocytes Complement |
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Acquisition of Pneumonia |
"CIAPEE" 1) Colonise Nasopharynx 2) Inhaled into alveolus 3) Adhesion + multiplication in alveoli 4) Evade immune system 5) Proliferate 6) Express virulence factors |
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typical bacterial pathogens |
extracellular has cell wall |
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atypical bacterial pathogens |
intracellular some have no cell wall |
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S. pneumoniae characteristics |
"IIICA" Immune evasion Invasins Inflammatory agents Capsule Adhesins |
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S. pneumoniae immune evasion |
- negatively charged capsule repels PMNs - Capsule switching (change capsule serotype) - |
