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6 Cards in this Set
- Front
- Back
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What is the TL article about, in general?
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Deficiencies in leukocytes that impair the phagocytic response during infection.
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What are the three kinds of congenital neutropenia? Why are these considered leukodeficiencies?
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Cyclic, severe, and Swachman-Diamond syndrome. There are not enough neutrophils to combat infection in all three diseases.
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What is the physiological characteristic of CYCLIC neutropenia?
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On an average 21-day cycle, sufferers have an extremely low (<200) neutrophil count for 3-6 days.
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How many patients die from acute infection in CYCLIC neutropenia?
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10%
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What are the clinical diseases in CYCLIC neutropenia?
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gingivitis, stomatitis, cellulitis
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Where does leukocyte development stop in CYCLIC neutropenia?
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At myelocytes.
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