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44 Cards in this Set
- Front
- Back
what are Actin and myosin grouped as?
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Microfilaments
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structural microfilaments, composed of F actin
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Actin
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monomeric actin subunites
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G actin
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Gactins polymerized into a double helix
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F actin
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a regulatory alpha helix in muscle, that wraps around F actin myofilaments
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Tropomyosin
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Regulatory subints that respind to Ca +2 to interact with tropomysoin and induce muscle contraction
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Troponins (C,T,I)
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actin croll linking protein that forms networks in erythrocytes
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Spectrin
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actin cross linking protein that forms networks in striated muscle. Duchenne muscular dystophy is a sex linked mutation of the dystrophin gene
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Dystrophin
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a structural microfilament as well as a motor protein for actin
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Myosin
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actin and myosin associated with each other
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Actomyosin
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bundles of actomyosin anchored to the basal surface of fibroblasts, which are themselves attached to the substratum. These fibers produce tensiona cross a cell layer.
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Stress fibers
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what group are alpha and beta tubulin categorized in? (thick filaments)
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Microtubiles
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microtubular cross linking proteins that form networks
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Tau and MAPs (microtubular associated proteins)
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a microtubule motor protein for flagella, cilia, axons and kinetochores
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Dynein
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Thin filaments
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Microfilaments
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what group are Keratins and nuclear lamins in?
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Intermediate Filaments
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which two fiber classes are for structure AND motility
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Microfilaments and Microtubules
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Which class of fibers is only has a structural function?
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Intermediate Filaments
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uses ATP as energy
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Microfilaments
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Uses GTP as energy
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Microtubules
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Structural components of the ctyoskeleton. they are complexes composed of proteins that all have similar alpha helical cores, but distinctive terminal domains
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Intermediate Filaments
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A major intermediate filament of epithelial cells, (hair and nails)
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Keratin
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intermediate filaments supportingthe nuclear membrane
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Nuclear Lamins
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what can be found in the extracellular matrix?
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Collagen
Hyaluronans Proteoglycans Heparin Laminin Fibronectin |
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extracellular matric fibers that resist stretching, composed of 3 helices coiled around each other in a triple helix
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Collagen
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large polysaccharides of the extracellular matrix composed of disaccharide repeats of modified sugars
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Hyaluronans
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extracellular matrix cross linking protein forming networks in the basal lamina
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Laminin
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ECM components, composed of core proteins attached to one or more large palysaccharide side chains of modified disaccharides, similar to hyaluronan
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Proteoglycans
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A proteoglycan secreted by mast cells
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Heparin
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ECM cross linking protein with multiple binding domains for different factors (heparin, collagen integrin, etc.)
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Fibronectin
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List the junction specific factors
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Integrin
Anlyrin Adaptor proteins Cadherins |
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the transmembrange protein for hemidesmosomes and adhesion plaques. it is bound by an adaptor protein or plaque on the cytoplasmic side of the membrane and fibronectin on the extracellular side.
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Integrin
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a membrange-microfilament binding protein that bings spectrin in erythrocytres and desmin from muscle sarcomeres
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Ankyrin
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factors that link actomyosin filaments to integrin in adhesion plaques or cadherin in belt desmosomes
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Adaptor Proteins
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a family of calcium dependant transmembrane proteins that tie similar cells together. one is used as a belt desmosome
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Cadherin
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isolated Aspot welds at joining the intermediate filament ctytoskeletons of two cells at their lateral surfaces
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Spot Desmosomes
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structures that anchor the intermediate filament cytoskeleton of an epithelial cell to the basal lamina
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Hemidesmosome
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membrane associated proteins that anchor the microfilament cytoskeleton to the plasma membrane by binding actin cross linking proteins
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Membrange-microfilament binding protein
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structures that anchor microfilament stress fibers to the basal surface of many cells, particularly epithelial cells
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adhesion plawues
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thin bands of membrane around the apical perimeters of epithelial cells, held closely together by priteins such as occludin and claudin. they seal cells to prevent diffusion of molecules across the epithelium.
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Tight Junctions
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rows of structures anchoring actin microfilaments to the apical surface of epithelial cells, just beneath the tight junction
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Belt Desmosomes
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microfilaments bundles (actin and myosin) that encircle the apical perimeter of epithelial cells at the level of the belt desmosomes
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Circumferential Belt
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Transmembrane complexes that allow diffusion of small molecules between cells to vesicles
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Gap Junctions
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a system of interconnected components that interact in a dymanic manner to form a stable, functional structure.
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Tensegrity
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