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44 Cards in this Set

  • Front
  • Back
what are Actin and myosin grouped as?
Microfilaments
structural microfilaments, composed of F actin
Actin
monomeric actin subunites
G actin
Gactins polymerized into a double helix
F actin
a regulatory alpha helix in muscle, that wraps around F actin myofilaments
Tropomyosin
Regulatory subints that respind to Ca +2 to interact with tropomysoin and induce muscle contraction
Troponins (C,T,I)
actin croll linking protein that forms networks in erythrocytes
Spectrin
actin cross linking protein that forms networks in striated muscle. Duchenne muscular dystophy is a sex linked mutation of the dystrophin gene
Dystrophin
a structural microfilament as well as a motor protein for actin
Myosin
actin and myosin associated with each other
Actomyosin
bundles of actomyosin anchored to the basal surface of fibroblasts, which are themselves attached to the substratum. These fibers produce tensiona cross a cell layer.
Stress fibers
what group are alpha and beta tubulin categorized in? (thick filaments)
Microtubiles
microtubular cross linking proteins that form networks
Tau and MAPs (microtubular associated proteins)
a microtubule motor protein for flagella, cilia, axons and kinetochores
Dynein
Thin filaments
Microfilaments
what group are Keratins and nuclear lamins in?
Intermediate Filaments
which two fiber classes are for structure AND motility
Microfilaments and Microtubules
Which class of fibers is only has a structural function?
Intermediate Filaments
uses ATP as energy
Microfilaments
Uses GTP as energy
Microtubules
Structural components of the ctyoskeleton. they are complexes composed of proteins that all have similar alpha helical cores, but distinctive terminal domains
Intermediate Filaments
A major intermediate filament of epithelial cells, (hair and nails)
Keratin
intermediate filaments supportingthe nuclear membrane
Nuclear Lamins
what can be found in the extracellular matrix?
Collagen
Hyaluronans
Proteoglycans
Heparin
Laminin
Fibronectin
extracellular matric fibers that resist stretching, composed of 3 helices coiled around each other in a triple helix
Collagen
large polysaccharides of the extracellular matrix composed of disaccharide repeats of modified sugars
Hyaluronans
extracellular matrix cross linking protein forming networks in the basal lamina
Laminin
ECM components, composed of core proteins attached to one or more large palysaccharide side chains of modified disaccharides, similar to hyaluronan
Proteoglycans
A proteoglycan secreted by mast cells
Heparin
ECM cross linking protein with multiple binding domains for different factors (heparin, collagen integrin, etc.)
Fibronectin
List the junction specific factors
Integrin
Anlyrin
Adaptor proteins
Cadherins
the transmembrange protein for hemidesmosomes and adhesion plaques. it is bound by an adaptor protein or plaque on the cytoplasmic side of the membrane and fibronectin on the extracellular side.
Integrin
a membrange-microfilament binding protein that bings spectrin in erythrocytres and desmin from muscle sarcomeres
Ankyrin
factors that link actomyosin filaments to integrin in adhesion plaques or cadherin in belt desmosomes
Adaptor Proteins
a family of calcium dependant transmembrane proteins that tie similar cells together. one is used as a belt desmosome
Cadherin
isolated Aspot welds at joining the intermediate filament ctytoskeletons of two cells at their lateral surfaces
Spot Desmosomes
structures that anchor the intermediate filament cytoskeleton of an epithelial cell to the basal lamina
Hemidesmosome
membrane associated proteins that anchor the microfilament cytoskeleton to the plasma membrane by binding actin cross linking proteins
Membrange-microfilament binding protein
structures that anchor microfilament stress fibers to the basal surface of many cells, particularly epithelial cells
adhesion plawues
thin bands of membrane around the apical perimeters of epithelial cells, held closely together by priteins such as occludin and claudin. they seal cells to prevent diffusion of molecules across the epithelium.
Tight Junctions
rows of structures anchoring actin microfilaments to the apical surface of epithelial cells, just beneath the tight junction
Belt Desmosomes
microfilaments bundles (actin and myosin) that encircle the apical perimeter of epithelial cells at the level of the belt desmosomes
Circumferential Belt
Transmembrane complexes that allow diffusion of small molecules between cells to vesicles
Gap Junctions
a system of interconnected components that interact in a dymanic manner to form a stable, functional structure.
Tensegrity