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15 Cards in this Set
- Front
- Back
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Majority of B cell binding and proliferation occurs in the lymphoid structure known as a
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Germinal center
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What secondary lymphoid organ are encapsulated T B and S cells found in
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Lymph Node and Spleen
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Where do encapsulated antigens in lymph nodes go to? Spleen?
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Tissues, Blood stream
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Where do unencapsulated antigens move to (secondary lymphoid organ)
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MALT
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Where do MALT antigens move to in an immune response
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The mucosal surfaces
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In both B and T cells a small fraction remain unactivated as
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Memory cells
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Do T cells undergo affinity maturation
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No
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Immature dendritic cells present antigens that they've taken up complexed with ____
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MHC II
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T1cells act on
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B cells
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T2 cells act on
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Macrophages
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Both Tcell types bind and give rise to low affinity Ig_
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IgM
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The recognition of the processed antigen by the Th cell and of WHAT causes activation of the B cell
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CD40, CD40L
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In the light/dark zone of the germinal center, B cells encounter the antigen on the surface of dendritic cells and only cells with high affinity for that antigen survive
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Light Zone
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Where does clonal expansion of B cells occur in the germinal center? Dark/Light zone
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Dark Zone
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What type of feedback (negative or positive) is caused by IgM and IgG activity
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IgM causes positive feedback
IgG causes negative feedback |
