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5 Cards in this Set
- Front
- Back
Daily Fluid Secretion + Absorption |
500ml bile + 1500ml pancreatic juice 1500ml fluid secreted from bowels 8500ml absorbed by SI 400-1000ml absorbed by LI 100ml water lost from body |
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Sites of Absorption |
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Absorption of K+, Ca2+ and iron |
K+ paracellular solvent drag Ca2+ 1) vitamin D increases calcitriol synthesis by liver/kidneys 2) Calcitriol stimulates Ca2+ uptake via TRPV 3) Ca2+ binds to calbindin (buffer) Iron 1) Fe3+ reduced to Fe2+ by reductase 2) Binds to ferritin intracellularly or transferrin in blood |
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Role of motilin |
Increases MMCs and gastric emptying by increasing sensitivity to local motor reflexes |
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LI motility |
1) segmentation 2) mass/propulsive movement - initiated by intrinsic reflex pathways - enhanced by vagal neurones - gastrin and CCK increase colon excitability by sensitizing parasympathetic reflex pathways |