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13 Cards in this Set
- Front
- Back
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What are the 4 types of cells associated with bone connective tissue?
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Osteoprogenitor cells
Osteoblasts Osteocytes Osteoclasts |
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What cell is located within both the periosteum and endosteum and gives rise to cells that become osteoblasts?
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Osteoprogenitor cells
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What are osteoblasts? What does it secrete?
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The "building" cell, they secrete the initial semisolid form of bone matrix, called "osteoid."
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What is an osteoid?
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What the osteoblasts secrete, it later calcifies to become bone.
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When do osteoblasts differentiate into osteocytes?
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When they get stuck in the matrix (osteoid) they secrete, they differentiate into an osteocyte.
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What is the function of the osteocyte?
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They maintain the bone matrix and detect mechanical stress on a bone.
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When does the osteoblast know to grow more bone?
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When the osteocyte detects the stress, the information is communicated to the osteoblasts.
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What are the 3 characteristics of the osteoclast?
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Large, multinuclear, and phagocytic
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Where did the osteoclasts derrive from?
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Appeared to be derived from bone marrow cells similar to those that produce monocytes in blood.
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What is the osteoclast's role?
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Break down bone in a process called osteolysis.
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What is osteolysis?
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The process of breaking down bone.
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What is meant by balancing bone growth by building and breaking down?
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Osteoclasts remove matrix, osteoblasts add it. If blast is more active, the bone becomes stronger, if clast is more active, the bone becomes weaker.
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What is Ostetitis deformans?
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also known as paget's disease
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