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65 Cards in this Set

  • Front
  • Back

What is the layer covering the heart and proximal ends of blood vessels?

Answer: pericardium

What is the outer layer of the pericardium?

Answer: the fibrous pericardium

What is the middle layer of the pericardium?

Answer: the parietal layer of the serous pericardium

Where is the serous fluid around the heart?

Answer: between the parietal and visceral layers of the serous pericardium

What is the inner layer of the pericardium?

Answer: The visceral layer of the serous pericardium

What is the relationship between the parietal and visceral layers of the pericardium?

Answer: they make a continuous sheet that is folded on itself

What is the visceral layer of the pericardium also called?

Answer: the epicardium

What is pericarditis?

Answer: bacterial or viral infection causes the layers of the pericardium to stick together (fibroblasts)

What makes up the pericardial sac?

Answer: the fibrous and parietal layers

What is the function of the parietal & visceral layers of the pericardium?

Answer: produce serous fluid to reduce friction

What are the layers of the pericardium from superficial to deep?

Answer: fibrous, parietal, pericardial cavity, and visceral

What are the layers of the cardiac wall from superficial to deep?

Answer: epicardium, myocardium, endocardium

What is the epicardium responsible for?

Answer: serous fluid production & fat storage

What is the myocardium responsible for?

Answer: muscle contraction to pump the heart

What is the endocardium responsible for?

Answer: slippery lining of all heart structures

What is the endocardium made of?

Answer: epithelial and connective tissue

What is endocarditis?

Answer: a bacterial infection of the endocardium that occurs in immunocompromised patients, frequently after dental work, that can permanently scar/weaken the heart.

How do veins and arteries differ in utero?

Answer: Veins carry oxygenated blood from the placenta to the heart and arteries carry deoxygenated blood from the heart to the placenta.

What bypasses the liver and directs blood directly to the inferior vena cava?

Answer: ductus venosus

What bypasses the lungs and directs blood from the pulmonary trunk to the aorta?

Answer: ductus arteriosus

What bypasses the lungs and directs blood from the right atrium to the left atrium?

Answer: foramen ovale

What does the foramen ovale eventually become after birth?

Answer: fossa ovalis

What does the ductus arteriosus eventually become after birth?

Answer: ligamentum arteriosum (fibroblasts)

What is systole and diastole?

Answer: systole is contraction, diastole is relaxation

What is the lubb sound?

Answer: ventricular systole; the atrioventricular nodes close

What is the dupp sound?

Answer: ventricular diastole; the pulmonary & aortic valves close

How much does the average adult heart weigh?

Answer: 300 grams

What is the postero-superior surface of the heart?

Answer: the base

What is the inferior end of the heart that points anteroinferiorly to the left?

Answer: the apex

What side of the heart receives deoxygenated blood?

Answer: the right side

What side of the heart receives oxygenated blood?

Answer: the left side

Does the atrium or ventricles receive blood?
Answer: atrium
Does the atrium or ventricles pump blood?
Answer: ventricles
What is the largest chamber of the heart?
Answer: left ventricle; it is responsible for systemic circulation
What does the pulmonary trunk receive blood from?
Answer: right ventricle
Where does the pulmonary trunk deliver blood?
Answer: the lungs
What does the aorta receive blood from?
Answer: left ventricle
Where does the aorta deliver blood
Answer: systemic circulation
What are the two types of circulation?
Answer: pulmonary & systemic
Where do the venae cavae drain?
Answer: superior and inferior vena cava drain into the right atrium
Where do the pulmonary veins drain?
Answer: left atrium
Where are the atrioventricular valves?
Answer: between the atrium & ventricles on each side
Which AV valve is the tricuspid?
Answer: right AV valve
Which AV valve is the mitral?
Answer: left AV valve
Which AV valve is the bicuspid?
Answer: left AV valve
Where are the semilunar valves?
Answer: between the left ventricle & aorta and between the right ventricle & pulmonary trunk
Where is the coronary sulcus?
Answer: externally, between the atria & ventricles
Where is the interventricular sulcus?
Answer: externally, between the ventricles. It marks a line from the coronary sulcus to the apex.
What are the three veins that empty into the right atrium?
Answer: superior vena cava, inferior vena cava, and coronary sinus
What are the 4 functions of the fibrous pericardium?
Answer: structural support, anchors heart valves, framework for cardiac muscle attachment, & electric insulator (prevents simultaneous contraction)
What are impulse nodes and bundles?
Answer: cardiac muscle cells that are not contractile but initiate or conduct impulses
Which node is known as the pacemaker?
Answer: sinoatrial node
What is the conduction pathway between both atrial and ventricular myocardium?
Answer: atrioventricular node
What are the bundles that conduct impulses toward the ventricular myocardium?
Answer: Atrioventricular bundle
What are the bundles that deliver the impulses to the myocardial fibers?
Answer: Purkinje fibers
What happens if any of the nodes or bundles other than the pacemaker initiates muscle contraction?
Answer: arrhythmias, cardiac arrest, death
What is the resting membrane potential of nodal cells?
Answer: -60mV
At resting membrane potential, where is the calcium, potassium, and sodium?
Answer: more calcium & sodium outside the cell, more potassium inside the cell
How many cardiac contractions happen in a heartbeat?
Answer: Two. Atria then ventricles
Do nodal cells have a stable resting membrane potential?
Answer: no; they spontaneously depolarize
Describe the events leading to an action potential.
Answer: Previous repolarization causes voltage-gated sodium & calcium channels to open, allowing them entrance into the cell. -40mV threshold reached. Voltage-gated calcium channels open, allowing more calcium in, making the cell slightly positive (depolarization). Calcium channels close & voltage-gated potassium channels open, allowing potassium to leave, causing repolarization.
Describe the action potential's path.
Answer: AP moves from SA node to atrial sarcolemma. Conduction slows due to smaller fibers & fewer gap junctions in ventricles, allowing ventricular filling. The AP then moves from the AV node along the AV bundle to the Purkinje fibers, then propagated through the ventricular sarcolemma.
What are the electrical events of the cardiac muscle cells?
Answer: Action potential reaches cell, causing fast voltage-gated sodium channels to open until cell reaches +30mV (depolarized). Voltage-gated potassium channels are triggered then slow voltage-gated sodium channels. The sarcoplasmic reticulum releases more calcium, thus no electrical change (plateau). Voltage-gated calcium channels close. Potassium continues to leave until cell reaches -90mV again.
Describe the crossbridge cycling process.
Answer: calcium binds to troponin, myosin heads attach to actin, myosin head swivels, ATP binds to myosin head, releasing it from the actin, ATP is split & myosin head resets, calcium is released.
Why can cardiac muscle cells not exhibit tetany?
Answer: The plateau phase prevents repolarization from happening right away