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17 Cards in this Set

  • Front
  • Back
Aliskiren
direct renin inhibitor
tx of primary HTN
New, not widely used, specific inh
Angiotensins
maintain blood volume, raise bp
an oligopeptide in the blood that causes vasoconstriction, incr bp, and release of aldosterone from the adrenal cortex(promotes Na retention)
Bosentan
Endothelial receptor antagonist
tx of pulmonary artery hypertension (PAH)
nonselective ETa/ETb receptor blocker
contraindicated during pregnancy
Bradykinin
a peptide that causes blood vessels to enlarge (dilate), therefore lowers bp
ACE inh inhibit degradation of bradykinin (increase bradykinin)
Captopril
ACE inh
contraindicated during pregnancy & bilateral renal artery stenosis
lower bp, treat heart failure, prevent or delay progression of renal disease in pts with (non)diabetic nephropathies
Endothelins
proteins that constrict blood vessels and raise bp
when over-expressed contribute to heart disease
Losartan
Angiotensin II Receptor Blocker (ARB)
contraindicated during pregnancy & bilateral renal artery stenosis
nitroglycerin
nitrates
isosorbide dinitrate and mononitrate
nitrates
verapamil
Ca channel blockers
nondihydropyridines
diltiazem
Ca channel blockers
nondihydropyridines
nifedipine
Ca channel blockers
dihydropyridines (prototype)
amlodipine
Ca channel blockers
dihydropyridines
hydralazine
vasodilators
minoxidil
vasodilators
nitroprusside
vasodilators
sildenafil
vasodilators