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4 Cards in this Set
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Does ventricular tachycardia/ventricular fibrillation (VT/VF) affect prognosis in patients undergoing percutaneous coronary intervention (PCI) in the setting of ST-elevation myocardial infarction (STEMI)?
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Conclusions: In patients undergoing PCI for STEMI, VT/VF markedly increases the risk of mortality at 90 days, particularly when the VT/VF occurs after PCI.
Perspective: VT/VF in the first 48 hours of STEMI previously was thought to not have long-term prognostic implications. The results of this study and others indicate that VT/VF is a strong independent predictor of death at 90 days. Whether early treatment with an implantable cardioverter defibrillator improves outcomes in these patients is unclear and requires further study. |
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Sudden death from cardiac causes remains a leading cause of death among patients with congestive heart failure (CHF). Treatment with amiodarone or an implantable cardioverter–defibrillator (ICD) has been proposed to improve the prognosis in such patients. Which one offer a better outcome?
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In patients with NYHA class II or III CHF and LVEF of 35 percent or less, amiodarone has no favorable effect on survival, whereas single-lead, shock-only ICD therapy reduces overall mortality by 23 percent.
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We tested the hypothesis that prophylactic cardiac-resynchronization therapy in the form of biventricular stimulation with a pacemaker with or without a defibrillator would reduce the risk of death and hospitalization among patients with advanced chronic heart failure and intraventricular conduction delays. What is the outcome?
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In patients with advanced heart failure and a prolonged QRS interval, cardiac-resynchronization therapy decreases the combined risk of death from any cause or first hospitalization and, when combined with an implantable defibrillator, significantly reduces mortality. Copyright 2004 Massachusetts Medical Society
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Cardiac resynchronization therapy (CRT) through biventricular pacing is an effective treatment for heart failure (HF) with a wide QRS; however, the outcomes of patients requiring CRT and implantable cardioverter defibrillator (ICD) therapy are unknown.To examine the efficacy and safety of combined CRT and ICD therapy in patients with New York Heart Association (NYHA) class III or IV congestive HF despite appropriate medical management. What is the outcome?
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Cardiac resynchronization improved quality of life, functional status, and exercise capacity in patients with moderate to severe HF, a wide QRS interval, and life-threatening arrhythmias. These improvements occurred in the context of underlying appropriate medical management without proarrhythmia or compromised ICD function.
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