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38 Cards in this Set

  • Front
  • Back
Describe nucleus of cardiac cell
In the middle of the cell and elongated
2 components of the intercalated discs
Lateral component - parallel with the filaments

Transverse component - perpendicular to the filaments
T tubules are located at the level of _
Z lines
Endoplasmic reticulum of the muscle – in the cardiac muscle it forms irregular, poorly organized network at the periphery of the muscle cells
Sarcoplasmic reticulum
Sarcoplasmic reticulum cysternae at the Z lines storing Ca++
Terminal cisternae
Terminal cisternae interacts with T tubules forming _

What do they form in skeletal muscle

Depolarization of the T tubule membrane triggers _
release of Ca++ from the sarcoplasmic reticulum triggering muscle contraction
Dark band (mostly thick myosin filaments in the relaxed muscle)
A line
Light band (mostly thin actin filaments)
I line
darker line at the middle of the I line
Z line
portion of the muscle cell between two Z lines (2-3 μm)
middle of the sarcomeres
M line
Which line decreases in contraction
I line
double helix molecule, composed of G actin subunits
F - actin
two double helix polypeptide chains – masks the myosin binding site of actin in resting muscle
Cause of the rigor mortis
Myosin head is tightly bound to the actin molecule of the thin filament when ATP is not attached to the myosin head
Type of cells in conducting system
Modified myocytes
-irregular accumulations of small muscle fibers
-no intercalated discs
-few myofibrils; lack striations
-surrounded by rich collagen stroma
-highly vascular
-Enlarged fibers
-Vacuolated cytoplasm
-High glycogen content
-Few myofibrils
Purkinje fibers
The visceral and parietal pericardium is composed of
Mesothelial cells and fibrocollagenous tissue
_is composed of mesothelial cells with collagen and elastic fibers
Fibrous pericardium
between the visceral and parietal pericardium – contains fluid
Pericardial cavity
Endocardium is thicker in _
Irregular collagen fibers and some conducting fibers - what layer of endocardium
regular collagen and elastic fibers with myofibroblasts - what layer of endocardium
flat endothelial cells; continuous with endothelium of great vessels - what layer of endocardium
3 layers of valves
Tunica fibrosa

Tunica spongiosa

Tunica ventricularis
dense fibrocollagenous plate from the fibrous skeleton forming the core of the valve
Tunica fibrosa
loose connective tissue + endothelium on the atrial or vascular side of the valve: shock absorber
Tunica spongiosa
dense connective tissue + endothelium on the ventricular side of the valve. Continues in the chordae tendinae.
Tunica ventricularis
damage from disease in childhood --> scarring and collagen scar-->
valve becomes rigid
Rheumatic heart disease
aortic valve disease
collagen scar and Ca++ deposits
Calcific heart disease
endothelium, basal lamina, loose connective tissue with smooth muscle cells and occasional macrophages, internal elastic membrane - what layer of vessel
Tunica intima
smooth muscle and elastic fibers arranged circumferentially, external elastic membrane – large in arteries, indistinct in veins and virtually non-existent in small vessels - what layer of vessel
Tunica media
collagen and occasional smooth muscle; includes vasa vasorum and nervi vasorum - what layer of vessel
Tunica adventitia
Rodlike inclusions in the cytoplasm containing von Willebrand factor
Where are they located?
Weibel Palade bodies

Maintains non-thrombogenic barrier between platelets and subendothelial tissue – anticoagulants (thrombomodulin) and antithrombogenic agents (prostacyclin, tissue plasminogen activator-TPA). Damage results in release of prothrombogenic agents (von Willebrand factor)--> clotting. This is a function of ?
formed by macrophages & smooth muscle cells accumulate oxydized LDL
Foam cells