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227 Cards in this Set

  • Front
  • Back
the force that stretches the myocardium prior to contraction is called what?
preload
what is preload?
the force that stretches the myocardium prior to contraction
how does SV change with preload?
↑preload → ↑SV
what conceptually is an estimate of preload?
estimated by end-diastolic volume or end-diastolic pressure
the forces that oppose ventricular ejection are called what?
afterload
how does SV change with afterload?
↑afterload → ↓SV
how can afterload be modified pharmacologically?
by altering the PVR
what component of afterload can give you an estimate of the peripheral vascular resistance (PVR)
aortic pressure
the intrinsic, load-independent ability of cardiac muscle to shorten; or "the strength of the myocardium" is called what?
contractility
what is contractility?
the intrinsic, load-independent ability of cardiac muscle to shorten; or "the strength of the myocardium"
how does SV change with contractility?
↑contractility→ ↑SV
how do you calculate cardiac output?
CO = HR (bpm) x SV (vol/beat)
define heart failure
a syndrome of clinical signs that results from impaired emptying or filling of the heart
how does heart failure relate to heart disease?
heart disease can cause heart failure, but so can other things
what is the prognosis for heart failure?
heart failure is terminal unless the cause can be eliminated
what is the most common clinical sign of LV congestive heart failure?
pulmonary edema
what is the most common clinical sign of RV congestive heart failure?
ascites
what is a volume overload?
↑diastolic volume of the ventricle
what is contractile dysfunction?
a primary disorder of the myocardium that impairs the ability of the myocardium to generate systolic force
what is diastolic dysfunction?
impaired filling of the heart
in which animal is diastolic dysfunction most common?
cats
what are some clinical signs of left-sided and right-sided congestive heart failure?
- left-sided: cough, dyspnea, exercise intolerance (dogs & horses)
- right-sided: ascites, pleural effusion, peripheral edema
why is heart enlargement thought to result in coughing?
bronchial compression
what is the only non-invasive means to make a diagnosis of left-sided CHF?
thoracic radiography
in dogs with an acquired heart disease, what clinical sign is usually present?
left atrial enlargement
in cats what is the most common form of acquired heart disease?
myocardial disease
what is a limitation of echocardiography with regards to diagnosing cardiac dysfunction?
does not provide information regarding the consequences of cardiac dysfunction – one cannot make a diagnosis of CHF based on echo alone
what is the best method to diagnose arrhythmias?
EKG
what are some limitations of EKG with regards to diagnosing cardiac dysfunction?
cannot determine cardiac enlargement, murmurs, valvular disorders, etc.
what cardiac diagnostic is indicated when an animal presents with clinical signs such as cough or dyspnea?
thoracic radiography
what cardiac diagnostic is indicated when the cause of an enlarged radiographic cardiac silhouette is unclear and/or when an definitive etiologic diagnosis of heart disease is important?
echo
what cardiac diagnostic is indicated when the heart rate is inappropriately high, inappropriately low or inappropriately irregular?
EKG
what is the definition of heart disease?
any structural/functional cardiac abnormality
comment on the prevalence of a cough in cats, dogs, and horses, as a clinical sign of heart disease
- cats: rare
- dogs and horses: common
what is a normal heart rate for a
- canine?
- feline?
- equine?
- bovine?
- canine: 70 - 160
- feline: 160 - 240
- equine: 24 - 50
- bovine: 60 - 110
how does HR correlate to size in dogs?
it does not
what are the two important characteristics of an arterial pulse?
1. amplitude (strength) - clinically most important
2. quality - more subjective
what are five physiological parameters that determine arterial pulse?
1. STROKE VOLUME
2. aortic distensibility
3. resistance to flow (rate at which blood leaves the arterioles)
4. EDV of the arteries
5. HR
what is the most common cause of a weak (hypokinetic) arterial pulse?
most often reflects a small stroke volume associated with hypovolemia or sometimes, heart disease
what are two common causes of an absent arterial pulse?
1. thromboembolism
2. "artifact"
what are four common causes of a bounding (hyperkinetic) arterial pulse?
1. anemia
2. hyperthyroidism
3. aortic insufficiency (low diastolic pressure)
4. PDA (low diastolic pressure)
what determines the distension and height of a jugular pulse?
right atrial (and ventricular diastolic) pressure
central venous pulse:
- correct positioning of the animal
- in the horse, if > 8 cm, what does this suggest?
- standing (sternal)
- if > 8cm in the horse, suggests right heart failure, volume overload
what are two causes of mucous membrane pallor?
1. anemia
2. vasoconstriction
what causes cyanosis?
when [deoxyhemoglobin] ≥ 4 g/dL, independent of species or size of the animal
what are the two types of cyanosis and what causes them?
1. peripheral cyanosis - stasis of blood (low CO, thrombosis)
2. central cyanosis - lung disease, rarely heart defects (Tetralogy of Fallot)
where is the PMI in a healthy individual?
over the left apex
what is a thrill?
a palpable vibration of the chest wall associated with a high intensity murmur
what is the origin of the four heart sounds?
- S1: AV valve closure
- S2: semilunar valve closure
- S3: early diastolic filling
- S4: atrial contraction
what is "splitting" of heart sounds?
when aortic & pulmonic (or mitral & tricuspid) valve closures can be discerned from each other
what are four causes of splitting of S2?
(delayed semilunar valve closure caused by)
1. outflow tract stenosis
2. volume overload
3. bundle branch block / premature complexes
4. physiologic and associated with respiration
what is a cause of splitting of S1
delayed AV valve closure due to a bundle branch block
what causes systolic "clicks?"
mitral valve prolapse
in who are systolic clicks most common and what does this say about their heart?
- common in older small-breed dogs
- a precursor to mitral valve regurgitation
what is a "gallop" heart sound?
an audible S3 and/or S4
in small animals, when are gallop sounds most commonly heard?
when atrial pressures are high and the ventricle is close to its elastic limit
what is a murmur?
a prolonged series of vibrations that originates from the CV system
why can you hear a murmur?
because it results from turbulent blood flow
what are three determinants of blood flow character that can explain murmurs?
1. velocity - acceleration explains almost all murmurs
2. viscosity - anemia may explain a murmur when HCT < 17
3. diameter (rare)
what are five characterizations of murmurs?
1. intensity
2. timing (relative to cardiac cycle)
3. PMI
(4. configuration)
(5. quality)
what is a Grade 1/6 murmur?
very soft and focal
what is a Grade 2/6 murmur?
a soft murmur
what is a Grade 3/6 murmur?
a murmur of intermediate intensity
what is a Grade 4/6 murmur?
a loud murmur with no thrill or an intermittent thrill
what is a Grade 5/6 murmur?
a loud murmur with an associated thrill
what is a Grade 6/6 murmur?
a loud murmur with thrill and audible when stethoscope is lifted from chest
a murmur that is very soft and focal, is what grade?
Grade 1/6
a murmur that is a soft murmur, is what grade?
Grade 2/6
a murmur that is a murmur of intermediate intensity, is what grade?
Grade 3/6
a murmur that is a loud murmur with no thrill or an intermittent thrill, is what grade?
Grade 4/6
a murmur that is a loud murmur with an associated thrill, is what grade?
Grade 5/6
a murmur that is a loud murmur with thrill and audible when stethoscope is lifted from chest, is what grade?
Grade 6/6
what are the three timings of murmurs and what is their time interval with respect to the heart sounds?
1. systolic: S1-S2
2. diastolic: S2-S1
3. continuous: BEGINS DURING SYSTOLE AND PERSISTS AFTER S2
what is the most common cause of a continuous murmur?
PDA
what is a to-and-fro/bellows murmur?
a concurrent systolic and diastolic murmur. Not the same as a continuous murmur.
what are the two most common areas where a murmur PMI is heard and what valves are associated with them?
1. left heart base (aortic/pulmonic)
2. left apex (mitral)
when auscultating a cat, where on the body are you mist likely to hear a murmur?
along the borders of the sternum
what are two important murmur configurations, where they occur in the heart cycle, and the shape of the waveform?
1. ejection murmur: mid-systolic and diamond-shaped
2. regurgitant: mid-systolic and plateau-shaped
what are the three important characteristics of a murmur that an average vet should be able to describe?
1. intensity
2. timing
3. PMI
Murmurs that occur in the absence of structural cardiac disease in animals that are otherwise normal are called what?
innocent murmurs
in which animals are innocent murmurs heard?
puppies and kittens are most common; sometimes in adult horses
what is a flow, or "functional" murmur?
a murmur that increases in intensity with increasing cardiac output (e.g. athleticism, fever, thyrotoxicosis)
what are the two main physiological parameters measured by EKG?
1. rate
2. rhythm
what is the standard position of a dog or cat for EKG?
right lateral recumbency
where does the EKG lead II connect?
left leg
in the normal heart, in which direction does the heart depolarize in the sagittal, transverse, and dorsal planes?
- right → left
- cranial → caudal
- dorsal → ventral
what are the two types of EKG lead systems and how are they wired?
1. bipolar leads: negative and positive electrodes; leads I, II, III
2. augmented limb leads: positive (exploring) electrode and zero potential; aVR, aVL, aVF (Left, Right, Foot)
the dominant direction of ventricular activation is called what?
mean electrical axis
when ventricular activation is occurring normally, though the specialized conduction system, what should the QRS look like?
NARROW (≈ 0.7 seconds), usually upright
what is a major cause of syncope?
arrhythmias
what are the two general ways in which arrhythmias develop?
1. disease of the conduction system prevents initiation or propagation of the wave front
2. disease of the myocardium causes spontaneous depolarization of working myocytes (e.g. tachyarrhythmias)
Name the arrhythmia.
2nd degree AV block
Name the arrhythmia.
3rd degree AV block
Name the arrhythmia.
3rd degree AV block
Name the arrhythmia.
Atrial fibrillation (supraventricular tachycardia)
Name the arrhythmia.
atrial fibrillation (supraventricular tachycardia)
Name the arrhythmia.
supraventricular tachycardia
Name the arrhythmia.
ventricular tachycardia
Name the arrhythmia.
ventricular tachycardia followed by several ventricular premature complexes
what two general cardiac conditions are associated with the development of tachyarrhythmias?
1. structural cardiac disease
2. extra-cardiac disease
what are three extra-cardiac conditions that may result in tachyarrhythmias?
1. electrolyte abnormalities
2. acid-base disturbances
3. "autonomic imbalance"
what are two general causes of bradyarrhythmias?
1. disease (e.g., fibrosis) of the conduction system slows the rate of depolarization or "blocks" conduction
2. autonomic factors - high vagal tone (has the same functional effect as #1)
in EKG, what are the three parameters that are most commonly assessed to diagnose an arrhythmia?
1. heart rate
2. rhythm (regular or irregular)
3. what is the association between atrial and ventricular activity
what is required of a rhythm/arrhythmia associated with the sinus node?
a P wave of normal morphology preceding every QRS by a consistent and believable PR interval
a sinus arrhythmia depends on what extra-cardiac stimulus?
vagal discharge
sinus tachycardia is characterized by what heart rate in the
- dog?
- cat?
- horse?
- dog: > 160 bpm
- cat: > 240 bpm
- horse: > 50 bpm
sinus bradycardia is characterized by what heart rate in the
- dog?
- cat?
- horse?
- dog: < 70 bpm
- cat: < 140 bpm
- horse: < 24 bpm
an irregular, fast heart rate that is comprised of a normal PR interval and a normal QRS complex
supraventricular tachyarrhythmia
why is the QRS normal in a supraventricular tachyarrhythmia?
because the event occurs proximal to the bifurcation of the bundle of His
what diseases are associated with supraventricular tachyarrhythmias and why?
those that cause atrial distention (e.g. CVD, DCM, etc.) because they allow for a "critical mass" for a supraventricular ectopic event
what is supraventricular tachycardia?
three or more supraventricular tachyarrhythmia events in a row
disorganized electrical activity of the heart is called what?
fibrillation
what arrhythmia sounds like "bongo drums", "sneakers in a dryer", or "popcorn in a microwave"
atrial fibrillation
why does atrial fibrillation typically occur in horses and giant-breed dogs?
because you need the "critical mass" of heart muscle to support the arrhythmia
what type of arrhythmia is characterized by wide and bizarre QRS complexes? Why?
- ventricular premature complexes
- because the events are not occurring through the specialized conduction system
what is the definition of ventricular tachycardia?
if there are three or more ventricular premature complexes in a row
what is the outcome of a degenerative ventricular tachycardia?
ventricular fibrillation → death
what are two breeds of dog predisposed to ventricular tachycardia due to severe myocardial dysfunction?
1. Doberman Pinscher
2. Boxer
what are five extra-cardiac conditions that may result in ventricular tachyarrhythmias (and/or VTC)?
1. trauma (HBC)
2. GDV
3. splenic disease
4. neurologic disease
5. sepsis
what are three general reasons why extracardiac disease can cause ventricular tachyarrhythmias?
1. autonomic factors
2. electrolyte disturbances
3. acid-base disturbances
what is often characteristic of extra-cardiac ventricular tachyarrhythmias with respect to myocardial dysfunction?
they are often slow (< 160 bpm); "slow V-tach"; versus very high heart rates normally associated with V-tach
comment on the health implications of extra-cardiac "slow" ventricular tachycardia.
- well-tolerated by the patient
- electrically benign
- resolve spontaneously
define 1st, 2nd, and 3rd degree AV blocks.
- 1st Degree: PR prolongation
- 2nd degree: intermittent failure of AV conduction
- 3rd degree: complete failure of AV conduction
which AV blocks are associated with syncope?
2nd and 3rd degree AV blocks
what are three etiopathogenic causes of high 2nd degree or 3rd degree AV blocks?
1. idiopathic fibrosis (dogs)
2. myocardial disease
3. aortic valve endocarditis
what are three common causes of hyperkalemia?
1. urethral obstruction
2. oliguric renal failure
3. Addison's disease
what are three characteristics of hyperkalemia in an EKG?
1. wide QRS
2. P-waves of low amplitude or absent
3. peaked T-waves
what are three indications for Holter monitoring (ambulatory electrocardiography)?
1. diagnosis of syncope
2. assessment of arrhythmias detected by resting EKG
3. evaluation of antiarrhythmic therapy
how are tachyarrhythmias generally treated? Bradyarrhythmias?
- tachyarrhythmias: pharmacologically
- bradyarrhythmias: cardiac pacing
what are the three echocardiographic modalities?
1. M-mode
2. 2D
3. Doppler
what are the three standard images in M-mode echocardiography?
1. Left ventricle
2. mitral valve
3. Aorta / Left atrium
name a pro and con for (1) M-mode and (2) 2D echocardiography
1. excellent temporal resolution, but poor spatial resolution
2. excellent spatial resolution, but discrete frame rate
how is LV dilation / hypodynamic (hypokinetic) performance, for example, in dilated cardiomyopathy evaluated quantitatively with echocardiography? What are normal values for dogs?
- measured in %FS = (LVED-LVES)/LVED
- in most healthy dogs, 25 < %FS < 45
in echocardiography, how is LA size assessed and what are normal values?
- assessed by comparing left atrium to aorta diameter
- LA/Ao < 1.6 - 1.4 in dogs and cats (depending on mode and species)
what are the two Doppler echocardiographic conventions?
1. spectral doppler - flow towards the transducer = positive velocities
2. color flow Doppler: BART - blue away, red toward
what three pieces of information does Doppler echocardiography provide?
1. velocity of flow
2. direction of flow
3. character of flow
what are the three Doppler echocardiographic modalities and what information do they provide?
1. pulsed wave Doppler: quantification of physiologic velocities
2. continuous wave Doppler: quantification of supraphysiologic velocities
3. color flow Doppler: detection of flow disturbances
how can you determine change in pressure from one structure to another (e.g. left ventricle to aorta with a subaortic stenosis), if you know the velocities (from echocardiography) of blood flow at each site?
- use the simplified Bernoulli equation:
- ΔP = 4 (v2² - v1²)
- where v = velocity
almost all forms of congenital heart disease have what clinical sign?
murmur
if you find a murmur and diagnose congenital heart disease, but the patient has absolutely no clinical signs, what does that mean?
- most patients are healthy at time of detection
- lack of clinical signs does not imply good prognosis
in which species has congenital heart disease found to be heritable?
dogs
characterize an "innocent" murmur.
- always systolic
- always soft
what is the most appropriate treatment approach for congenital heart disease
mechanical means (i.e., surgery, interventional catheterization)
what are the three basic therapeutic approaches to treat congenital heart disease?
1. surgical (± pulmonary bypass: $$$)
2. interventional catheterization techniques
3. medical therapy
what are two common types of interventional catheterization techniques to treat congenital heart disease?
1. balloon dilation of obstructions
2. occlusion of shunts
PDA pathophysiology:
- direction of shunting
- abnormal loads on the heart
- three potential lesions to the heart if untreated or severe
- shunt is from left → right
- volume load on LA and LV
- myocardial dysfunction, mitral valve regurgitation, and CHF
what breeds of dogs are most commonly afflicted with a PDA? Sex predisposition?
- small breed females
- German Shepherd
- Sheltie
what are two CV-based clinical signs of a PDA on routine physical exam and auscultation?
1. continuous murmur
2. bounding arterial pulses from diastolic bleedoff
what are three important radiographic findings of a PDA?
1. dilation of aorta and main pulmonary artery
2. cardiomegaly due to LA/LV enlargement
3. pulmonary hyperperfusion
what are four important echocardiographic findings of a PDA?
1. LA/LV enlargement
2. mitral valve regurgitation
3. continuous disturbed flow within the MPA
4. ductus visible in left cranial parasternal images
what (type of) breed of dog is this?
brachycephalic (bulldog)
what defect does this dog have?
generalized cardiomegaly/pericardial effusion
to what is the arrow pointing in this normal dog?
left auricle
what defect does this dog have?
left atrial enlargement

note: the "cowboy straddle" in the bronchi
what defect does this dog have?
left atrial enlargement

note: bulge at 2:00-3:00 and "cowboy straddle" of the main stem bronchi
what defect does this dog have?
left ventricular enlargement
what defect does this dog have?
right heart enlargement due to heartworm disease
what defect does this dog have?
left heart enlargement with concurrent pulmonary edema
what defect does this dog have, as indicated by the arrow?
pulmonary trunk enlargement
to what is the arrow pointing in this normal dog?
aorta, right auricle, and pulmonary artery
to what is the arrow pointing in this normal dog?
left atrium
to what is the arrow pointing in this normal dog?
left ventricle
to what is the arrow pointing in this normal dog?
right ventricle
what position is this dog in?
left lateral recumbency
what defect does this dog have?
left atrial enlargement

NOTE: vertical caudal border, caudal and dorsal bulge, elevated carina, and split mainstem bronchi
what defect does this dog have?
severe left atrial enlargement
what defect does this dog have?
pericardial peritoneal diaphragmatic hernia
what is the defect in this dog?
right heart enlargement due to tricuspid insufficiency

note the wide heart and increased sternal contact
what defect does this dog have?
right heart enlargement due to pulmonic stenosis

note the "reverse-D" shape
what view of the dog is this?
right lateral recumbency
which view, VD or DV, is a more accurate representation of the heart in radiography?
DV
how does the inspiration/expiration change the evaluation of the radiograph of the heart?
looks bigger on expiratory
what is the best lateral view for a radiograph of the heart?
right lateral recumbency
what are two big differences between a brachycephalic dog and a normal dog when assessing the heart radiographically?
1. the apex may point more exaggerated to the left
2. exaggerated right deviation of the trachea
on a lateral view, what are four radiographic indications of right heart enlargement?
1. increased width
2. increased sternal contact
3. elevation of apex
4. elevation of trachea (if severe)
on a DV view, what are three radiographic indications of right heart enlargement?
1. "Reversed-D" appearance
2. ↓ distance from right heart border to right chest wall
3. apex shift to the left
on a lateral view, what are three radiographic indications of left heart enlargement?
1. enlargement of the caudodorsal border
2. dorsal deviation of the trachea (parallel to the spine)
3. may see caudal bronchi compression or separation of the bronchi
on a lateral view, what are four radiographic indications of left atrial enlargement?
1. vertical caudal border of the heart
2. caudal and dorsal bulge
3. elevated carina
4. separation of left and right mainstem bronchi
on a DV view, what are three radiographic indications of left atrial enlargement?
1. left auricle may bulge at 2:00 - 3:00
2. left atrium may produce increased opacity at the base of the heart
3. lateral "bow-legged cowboy" deviation of the stem bronchi
on a lateral view, what are two radiographic indications of left ventricular enlargement?
1. caudal border is elongated and upright
2. elevation of trachea
on a DV view, what are three radiographic indications of left ventricular enlargement?
1. rounding of left ventricular border
2. decreased space between left heart and left chest wall
3. increased length
on a lateral view, how does a pulmonary trunk enlargement appear?
bulge in the craniodorsal heart, often superimposed over the trachea
on a DV view, how does a pulmonary trunk enlargement appear?
bulge at 1:00 - 2:00
on a lateral view, how does ascending aortic enlargement appear?
bulge in the craniodorsal heart border (cranially slanted heart)
on a DV view, how does ascending aortic enlargement appear?
bulge from 11:00 - 1:00
on a lateral view, how does descending aortic enlargement appear?
usually not visible
on a DV view, how does descending aortic enlargement appear?
bulge in descending aorta, just below area of pulmonary trunk
in a lateral view, how does left heart enlargement appear?
- increased length of heart
- "beer belly"
what are two approaches to correct a PDA?
1. ligation following left thoracotomy
2. transcatheter ductal occlusion
what is the pathophysiology of pulmonic stenosis?
- a pressure gradient develops across the obstruction
- pressure load on the right ventricle
- right sided congestive heart failure (ascites) is a potential sequela
what breeds of dogs are most predisposed to pulmonic stenosis?
1. terriers
2. English bulldogs
what will you hear on auscultation of a pulmonic stenosis?
systolic murmur at the left heart base
describe the definitive diagnosis of pulmonic stenosis
- doppler echo required for definitive diagnosis and assessment of severity
- gradients > 80 mmHg constitute severe PS
what are three ways to treat a pulmonic stenosis?
1. interventional catheterization via balloon valvuloplasty (preferred as the initial treatment when indicated)
2. patch graft following temporary venous occlusion
3. definitive repair under bypass
balloon valvuloplasty to treat pulmonic stenosis:
- mortality
- efficacy
- relatively low mortality
- efficacy varies, but is favorable in dogs with a gradient > 80 mmHg, whether or not clinical signs present.
if a pulmonic stenosis is left untreated, what generally occurs?
severe congestive heart failure in the first three years of life, or sudden death
what is the pathophysiology of subaortic stenosis?
- in order to maintain normal systemic pressures and flow, the LV must generate abnormally high systolic pressures
- a pressure gradient develops across the obstruction
- pressure overload on the LV → concentric left ventricular hypertrophy
what are the pressure gradients for mild, moderate, and severe subaortic stenosis?
- mild: < 40 mmHg
- moderate: 40-80
- severe: > 80
comment on the predisposition of subaortic stenosis in Newfoundland dogs?
it is inherited as a polygenic trait
what are four dog breeds predisposed to congenital subaortic stenosis?
1. Newfoundland
2. Golden Retriever
3. Rottweiler
4. Boxer
what are two cardiovascular findings on physical exam, of subaortic stenosis?
1. systolic murmur over the left heart base
2. weak (hypokinetic) arterial pulse
diagnosis of subaortic stenosis:
- what if it is mild?
- what is the accepted screening method
- when is Doppler echo indicated?
- mild SAS has genetic implications
- auscultation is the screening method
- Doppler is indicated when a murmur is detected
comment on the treatment of subaortic shunts:
- definitive correction
- prognosis
- other palliative care
- definitive correction requires bypass
- however, this correction does not affect survival
- balloon dilation may be palliative
- β-blockade (atenolol) may helpfully decrease HR and myocardial oxygen demand
what role does subaortic stenosis play in congestive heart failure?
this is uncommon
what is the most common location for a ventricular septal defect?
in the membranous area "high" in the septum
describe the pathophysiology of a ventricular septal defect:
- shunting
- load on the heart
- clinical importance
- left-to-right shunt (in the absence of other factors)
- imposes a volume load on the LV and LA
- importance depends on size of the defect and presence of other defects
comment on the prevalence of ventricular septal defects in the cat
they are relatively common
what are three dog breeds predisposed to ventricular septal defects?
1. bloodhound
2. English bulldog
3. Shiba Inu
what findings on auscultation are associated with a ventricular septal defect that is large? Small?
- any size: systolic murmur
- small size: right apical thrill
how is a ventricular septal defect definitively diagnosed?
echo
how are ventricular septal defects treated?
- most VSD in small animals are small and do not require therapy
- large/complex: bypass
- medical therapy to lower BP and drugs like digoxin/pimobendan
what are two common lesions in the heart that concur with ventricular septal defects?
1. aortic valve insufficiency
2. right ventricular outflow tract obstruction
atrial septal defects:
- pathophysiology
- if a murmur exists, where does it come from?
- prevalence
- treatment
- ASD causes left → right shunting and imposes a volume load on the right atrium and ventricle
- murmurs result from a "functional pulmonary stenosis"
- ASD are relatively uncommon
- can be repaired per catheter or under bypass
abnormal development of the mitral and/or tricuspid valve is called what?
AV valve dysplasia
that are two outcomes (seen by echocardiography) of AV valve dysplasia?
1. regurgitation
2. stenosis
AV valve dysplasia:
- prevalence in cats
- dog breed most predisposed
- severity
- how is it fixed?
- relatively common in cats
- common in Labrador Retriever
- variable severity
- requires bypass to correct
what is cyanotic heart disease?
right → left shunts that result in venous admixture
cyanotic heart disease requires a shunt and one of what three other conditions?
1. tricuspid stenosis
2. severe pulmonic stenosis
3. pulmonary hypertension with elevated vascular resistance
what are two clinical signs of cyanotic heart disease?
1. exercise intolerance
2. complications of polycythemia
shunt reversal due to increased pulmonary vascular resistance is called what?
Eisenmenger's Physiology
right-to-left PDA:
- age of animal
- type of murmur
- key clinical sign
- treatment
- shunt occurs early in life
- typically, no murmur
- marked hind-limb exercise intolerance
- phlebotomy is palliative
what are the four conditions associated with Teratology of Fallot?
1. pulmonic stenosis
2. ventricular septal defect
3. right ventricular hypertrophy
4. aortic malposition
how is Teratology of Fallot treated?
- definitively under bypass
- phlebotomy / β-blockade may be palliative
to what is the arrow pointing in this normal dog?
Aorta
to what is the arrow pointing in this normal dog?
Left Venticle
to what is the arrow pointing in this normal dog?
Pulmonary Artery
to what is the arrow pointing in this normal dog?
Right Atrium