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21 Cards in this Set

  • Front
  • Back
Primary Cardiomyopathy
Cannot be attributed to a specific cause
Secondary Cardiomyopathy
Due to a specific cause, like:
-Ischemic
-Valvular
-HTN
-Inflammatory
-Metabolic
-Inherited
-Toxicity
-Peripartum
Etiology of DIlated Cardiomyopathy
-Infectious; acute viral myocarditis
-Toxic; alcoholic CM
-Inherited; Familial CM
-Peripartum
Pathophysiology of DCM
-Dilation & impaired sytolic contraction of Vs w/ myocyte damage
-Neurohumoral
-Adrenergic NS
-Renin-angiotensis-aldosterone
Clinical presentation of DCM
-Volume overload
-Fatigue
-Ascites
-Edema
-Pleural effusions
Tx of DCM
-Supportive
-Gen HF meds when stable
-Later, ICD
Etiologies of Hypertrophic Cardiomyopathy
-Familial
Pathophysiology of HCM
-LVH not due to P overload
-Vigorous systolic fnx but impaired diastolic fnx=elevated diastolic Ps
Clinical presentation of HCM
-Dyspnea
-Angina
-Syncope
-Arrythmia
+/-Bisferiens pulse & S4 gallop
Brockenbrough-Braunwald Sign:
-Failure of aortic pulse P to rise post PVC....in HCM
Tx of HCM
Medical:
-BB
-CCB
-Anti-arrhythmics
-Abx prophylaxis for endocarditis
Surgical:
-Myomyectomy
Dual chamber pacemaker
-EtOH septal ablasion
-AICD to prevent sudden death
Etiologies of Restrictive Cardiomyopathy
-Amyloid
-Sarcoidosis
-Hemochromotosis
-Endomyocardial fibrosis
Pathophysiology of RCM
-Infiltration of myocardium by abnormal substance, fibrosis, or scarring of endocardium
Clinical presentation of RCM
-R>L sided HF
-Dyspnea
-Orthopnea/PND
-Peripheral edema
-Ascites/Hemaptomegaly
*Clinically mimics conrtrictive pericarditis
Tx of RCM
-Tx underlying cause
-Diuretics
-Digoxin
-Anti-arrythmics
-Pacemaker
-Anticoagulation for thrombus
Inheritance pattern of DCM
-Autosomal dominant or recessive
-X-linked
-Mitochondrial
Abnormalities associated with inherited DCM
-Energy production
-Contractile force generation
Inheritance pattern of HCM
-Autosomal dominant
Abnormalities associated with inherited HCM
-Beta-myosin heavy chain
-Acute V arrhythmias can occur
Genetic testing for CM
-Usually screening via Echo or EKG
Surveillance & screening for CM
-Echo for LV size, wall thickness, fnx, valve Dz, & Ps
-EKG forArrhythmias, LVH, BBBs, & Q waves
-Cath lab for filling Ps, LVEF, & angiography
CXR for heart size, edema, & pleural effusions
-Blood tests
-Endomyocardial Bx