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31 Cards in this Set

  • Front
  • Back
heart disease from an abnormality in the myocardium
Cardiomyopathy
Cardiomyopathy results in what four things?
Changes in wall thickness
Changes in chamber size
Mechanical dysfunction
Electrical dysfunction
Almost exclusively genetic (autosomal dominant)
Usually asymmetric septal hypertrophy, though apical variant exists (particularly among Asians)
Causes small left ventricular volume leading to ↓cardiac output
Hypertrophic Cardiomyopathy
What are the signs and symptoms of hypertrophic cardiomyopathy?
Usually asymptomatic
Dyspnea is most common presenting complaint
Angina
Syncope
Ventricular Arrhythmias
What is noticed in the physical examination of hypertrophic cardiomyopathy?
Left ventricular lift
Loud S4 gallop
Systolic ejection murmur
Increases in intensity with decreased LV filling (standing)
Decreased in intensity with increased LV filling (squatting)
What is seen in the EKG studies and echocardiogram with hypertrophic cardiomyopathy?
ECG: LVH, large septal Q waves, nonspecific ST/T-wave abnormalities
ECHO, NUC, CARD MRI, Cath: LVH, septal hypertrophy, diastolic dysfunction
What is the Tx for hypertrophic cardiomyopathy?
Septal ablation
AICD
Prevent heart failure: β-Blockers, ACE-I, and/or CCB
Most common type of cardiomyopathy
Usually idiopathic, up to 30% have genetic cause
Dilated cardiomyopathy
What is the hallmark of dilated cardiomyopathy?
Hallmark: dilation of both ventricles & reduced contractile function
Who is the most likely patient with a dilated cardiomyopathy?
black males as most likely patient
What are the signs and symptoms of dilated cardiomyopathy?
Dyspnea is most common presenting complaint
Poor exercise tolerance
Heart failure
Fatigue
Palpitations
Presyncope or Syncope
What is seen in the physical exam with dilated cardiomyopathy?
Tachycardia
Tachypnea
JVD
Pulmonary rales
Ascites, hepatomegaly

*** Looks like heart failure
What is seen in the EKG, Echo and Chest X-Ray in dilated cardiomyopathy?
ECG: nonspecific ST/T wave abnormalities, ectopy
Chest X-Ray: heart failure signs (enlarged cardiac silhouette, pulmonary vascular congestion, pleural effusions)
ECHO, NUC, Cath: LV dilation and dysfxn with low EF
What is the Tx for dilated cardiomyopathy?
Treat for CHF: ACE-I, β-Blockers, Ald Antag, Diuretics, Digoxin
AICD, Bi-V Pacing/CRT
Rare: 1-5% of cardiomyopathies
Restrictive cardiomyopathy
What are the causes of restrictive cardiomyopathy?
Amyloidosis (most common)
Hemochromotosis
Sarcoidosis
Radiation exposure
Abnormal myocardial stiffness results in…
Increased diastolic filling pressure leading to

Decreased cardiac output leading to

Heart Failure
What are the signs and Sx of restrictive cardiomyopathy?
Chest pain
Palpitations
Congestive heart failure
What is seen in the physical exam with restrictive cardiomyopathy?
Congestive heart failure
What is done with lab/imaging studies in restrictive cardiomyopathy?
Rule in/out amyloidosis or hemochromatosis
Chest X-Ray: enlarged silhouette
ECHO: restrictive diastolic filling pattern is diagnostic
How do you Tx restrictive cardiomyopathy?
Decrease preload with loop diuretics
Treat arrhythmias
Treat any underlying identifiable cause if it exists
new onset heart failure with preceding viral syndrome
Myocarditis
What is the usual viral cause of myocarditis?
Usually Coxsackievirus B is the culprit but MANY viral causes
What are the signs and Sx of myocarditis?
Usually asymptomatic
If sx present, think heart failure sx
What is seen in the physical exam of myocarditis?
Fever (if caught during viral illness)
Tachycardia
Fluid overload (think CHF!!)
Systolic murmurs (MR and TR)
S3 and S4 gallops
What is seen with the lab and imaging studies with myocarditis?
↑ESR, ↑Cardiac enzymes (esp Troponin T or I and CK-MB)
ECG: nonspecific ST/T-wave abnormalities; ectopy, atrial arrhythmias, AV conduction delay, IVCD (e.g. LBBB)
Chest X-Ray: maybe CHF findings
ECHO, NUC: LV enlarged, reduced global function, +/- mural thrombi
How do you Tx myocarditis?
Pain relief with narcotics
Abx if bacterial cause
Treat CHF
Avoid NSAIDS and steroids
Careful: some will go on to develop DCM!!! Serial ECHO to monitor
Looks like dilated cardiomyopathy
Resolves with abstinence in most
Alcoholic Cardiomyopathy
Resembles dilated cardiomyopathy
CD4 count < 100
HIV Cardiomyopathy
May be dilated or hypertrophic
Results after prolonged untreated hypertension
Hypertensive Cardiomyopathy
AKA “Broken Heart Syndrome”
Can look EXACTLY like STEMI
Caused by catacholamine surge after traumatic event
More common in patients with h/o pulmonary disease
Takotsubo’s Cardiomyopathy