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38 Cards in this Set

  • Front
  • Back
What term describes the inadequate blood flow to any tissue?
Ischemia
What term describes persistent ischemia leading to permanent tissue damage?
Infarction
What term describes cell death (not apoptosis)?
Necrosis
What substances does the cardiovascular system transport?
Blood carries nutrients, waste products, hormones, electrolytes, water, and oxygen.
What are the two modes of transport used in the CV system?
Bulk Flow and Diffusion
What type of pressure is measured along the length of a BV?
Perfusion pressure
What type of pressure describes the difference between the inside and outside of a BV?
What is another name for this pressure?
Transmural pressure or Distending pressure
What causes a stroke?
A cerebral infarct
What is another name for a blood clot?
Thrombus
What happens if a thrombus interrupts blood flow in a coronary artery?
Myocardial ischemia leads to a myocardial infarction.
T or F:
Cerebral vascular disease and coronary artery disease are very common in veterinary medicine
False
These diseases are common in human medicine.
T or F:
Cardiac diseases are common in veterinary medicine.
True
These diseases are common in veterinary medicine
Are the Pulmonary and Systemic circulations arranged in parallel or in series with respect to one another?
Arranged in series; blood must go through the pulmonary followed by systemic then back to pulmonary
How many capillary beds does a RBC pass through in a single circuit (either pulmonary or systemic)?
Usually only one capillary bed
An exception to the one capillary bed rule is called what?
What are three examples of this exception?
Portal system
1) Splanchnic Circulation - allows nutrients absorbed in GI to be delivered to liver
2) Kidneys - allows kidneys to adjust water/electrolyte balance
3) Hypothalamic/hypophyseal portal system - allows for hormonal regulation
Define cardiac output
The volume of blood pumped each minute by one ventricle
How can cardiac output be estimated for most mammals?
CO = ~3L/min/m2 (surface area of animal)
T or F:
THe perfusion pressure for the systemic circulation is greater than the perfusion pressure for pulmonary circulation.
True!
Systemic circulation requires a greater pressure since there is a greater volume of blood and a much greater length of bloodflow.
Define Systolic pressure.
Define Diastolic pressure.
Systolic - the peak pressure achieved
Diastolic - the minimum pressure achieved
What is the "standard" systolic/diastolic pressure for systemic circulation?
For Pulmonary circulation?
120/80 - systemic
20/8 - pulmonary
Define mean aortic pressure? What is the mean aortic systemic pressure?
Average value of pulsatile pressure in aorta.
Average is 93 to 98 mm Hg (93 by Hall)
How do you calculate perfusion pressure for systemic circulation? For pulmonary circulation?
Mean aortic pressure (outflow) - mean inflow pressure at RA = systemic perfusion pressure
Mean pulmonic pressure (outflow from RV) - mean inflow pressure at left atrium = Pulmonary perfusion pressure
T or F:
Systemic circulation is high-pressure, low-resistance.
False
Systemic circulation is high-pressure, high-resistance
T or F
Pulmonary circulation is low-pressure, low-resistance.
True
Less pressure is necessary on the pulmonic side since there is less resistance to flow.
What percent of blood is in systemic circulation?
75% in systemic
25% in pulmonary
Where is most of the blood found in systemic circulation?
80% in venules and veins
15% in arteries and arterioles
5% in capillaries
What cardiovascular structure is known as a blood reservoir?
A high-pressure conduit?
A gate?
Exchange vessels?
Veins
Arteries
Arterioles
Capillaries
What is the difference between a metarteriole and a capillary?
True capillaries lack smooth muscle
How viscous is normal blood vs. water?
blood is ~3.5x thicker than water
What is the cellular fraction of a hematocrit called? What is in this fraction?
PCV - packed cell volume
RBCs, WBCs, platelets
What is the non-cellular fraction of a hematocrit called? If the blood is clotted, what is it called?
Plasma is the non-cellular fraction
Plasma without clotting factors is called serum
What is the normal canid hematocrit range?
35 - 57% PCV
What term describes the bluish-red color of deoxygenated (reduced) Hemoglobin?
Cyanotic
What modulates the ability of blood to carry oxygen?
Temperature, pH, DPG concentration, MHC (mean content of hemoglobin per RBC), and MCHC (mean cell hemoglobin concentration).
What is an abnormally high hematocrit PCV called? An abnormally low value?
High - polycythemia
Low - anemia
What term describes inadequate tissue circulatory profusion?
Shock
Name some types of shock:
Hypovolemic shock (volume loss)
Septic shock (infection)
Cardiogenic shock (heart failure)
Anaphylactic shock
Neurogenic shock
Where is the heart located?
Between the 4th and the 7th intercostal spaces