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20 Cards in this Set

  • Front
  • Back
Most patients with cardiomyopathies will present with what?
Heart Failure
Dilated Cardiomyopathy
Big heart with big cavity contracting poorly
Poor DIFFUSE systolic function
Genetic ALWAYS
Enlargement of all 4 cardiac chambers--proportion of size of cavity to thickness of walls
Myocyte hypertrophy interspersed with degeneration and atrophy
Neurohormonal activation(symp and RAA)
Hepatomegaly
What is mitral regurgitation and in what condition does it often happen?
Dilated Cardiomyopathy--leaflets of mitral valve can't contract and there is slippage--upon contraction some blood will flow back to the LA
A big LV = ?
Mitral valve regurgitation
BNP is often seen in what patients?
Dilated CM
What is alcoholic CM?
Alcohol inhibits mitoch. ox/phos and fatty oxidation in the heart--Holiday Heart Syndrome
What is peripartum CM? What happens?
Cardiac Dilatation and CHF developing around and after delivery--bed rest recovery, advanced CM later in life, or progressive heart failure
If someone has peripartum CM then what?
Further pregnancies should be completely avoided
What is ARVD?
Arrhythmogenic Right Ventricular Dysplasia--portions of RV myocardium are replaced with adipose and fibrosis
Chagas Disease
T. Cruzi causes heart disease in central America--autoimmune reaction to trypanosome that causes the problem--RBBB and Left Anterior Hemiblock--not diffuse(posterior wall and apical contractility)
A young athlete dies suddenly--what type of CM? Where does it occur? What is common in all cases of this CM type?
Hypertrophic CM--occurs in septum and LV free wall--ALL HAVE GENETIC COMPONENT that encode for contractile proteins
How does hypertensive CM present?
Myocardial fibers show extensive disarray with intervening fibrosis
With one type of CM, increased flow to the heart is alleviating. In the other it worsens the condition.
Alleviating--Hypertrophic CM
Worsening--Dilated CM
Restrictive Cardiomyopathy
Abnormally rigid ventricles with impaired diastolic function but normal systolic function--infiltration of the myocardium or hypertrophy are the underlying causes
What hypertrophy should you always biopsy?
Restrictive
What is Kussmaul's sign and what hypertrophy is indicated?
Upon Inspiration--jugular venous pressure does not fall and might increase because more blood is being brought to the veins but cannot enter the heart--indicates Restrictive CM
What causes Myocarditis?
Drug hypersense, radiation, or virus
What immune mediated injury to the heart is caused by coxsackievirus?
Myocarditis
What syndrome is stress induced CM?
Takotsubo--POSTMENOPAUSAL WOMEN and they recover--there is no enzymatic sign of problems
What should never be given to Takotsubo patients?
Thrombolytics