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126 Cards in this Set

  • Front
  • Back
T/F: Almost all cardiac defects in dogs and cats are associated with a cardiac murmur.
True
(p 134)
Can the clinical signs be directly correlated to the severity of disease associated with CHD?
no.

Most are asymptomatic- this is not a prognostic factor.
Newfie with a continous murmur has what?
PDA
What is the major limiting factor to treatment of CHD in animals?
lack of Cardiac Bypass
What is the mortality rate of untreated CHD?
high
What direction is blood shunted in PDA?
left-> right
PDA imposes a volume overload of what side of the heart?
LEFT atrium and ventricle

* therefore myocardial dysfunction and mitral valve regurgitation are potential consequences
Poodles, Pomeranians and Maltese are highly predisposed to ___, especially females.
PDA

Females 3x greater risk than male
What are the physical findings associated with PDA?
continuous murmur
bounding pulse (hyperkinetic)
___ is due to a right ventricular outflow tract obstruction usually results from valvular dysplasia.
pulmonic stenosis
What CHD causes right ventricular hypertrophy? LV hypertrophy?
Right-- pulmonic stenosis (in order to maintain normal pulmonary artery pressures and flow, the RV must generate abnormally high systolic pressure)

Left: Subvalvular aortic stenosis (same mechanism)
___ occurs commonly in:

Terriers
English Bulldogs
mini Schnauzers
Samoyeds
Pulmonic Stenosis
What is the most likely method of correction of pulmonic and subvalvular aortic stenosis?
percutaneous balloon valvulplasty

*surgical if that fails
*therapy is only palliative and instituted only after the onset of heart failure
Pulmonic stenosis imposes a pressure overload of the ____.
RV
What breeds are predisposed to Subvalvular Aortic Stenosis?
Large breeds
Golden Retrievers
Rottweilers
Boxers
Newfoundlands
German Shepherds
What is the most common clinical sign of severe SAS?
CS are uncommon in puppies
syncope and sudden death in young adults
Outflow tract obstruction results in a (systolic/diastolic) murmur.
systolic

*therefore pulse is hypOkinetic
T/F: CHF is common in dogs with SAS.
False

CHF is UNcommon in SAS
Ventricular Septal Defect is a (systolic/diastolic) defect.
systolic
Clinical importance of a VSD depends on 2 factors:
1- size
2- presence of other concurrent defects
What species are more commonly affected by VSD?
cats and horses
What dogs tend to be more commonly affected by VSD?
english springer spaniel
English bulldog
bloodhound
shiba inu
a VSD results in a ___ murmur due to the pressure difference between the ventricles (Drops to nearly zero during diastole).
systolic
T/F: Most VSDs in dogs and cats are small and well tolerated.
True

*systolic murmur
left to right shunting
volume overload of the LA, LV
Unlike VSD which shunts blood through the defect and immediately into the pulmonary circulation during _____, an ASD increases the _____ volume of the right ventricle.
VSD -- systole

ASD-- increases RV diastolic volume
Is an atrial shunt audible?
NO

*there may be relative pulmonic stenosis that creates an audible murmur
AV valve dysplasia is a relatively common defect in the ___, that can result in regurgitation (more common) or stenosis. it is UNCOMMON and generally inaudible.
CAT
Cyanotic heart disease result when there is shunting (due to ASD, VSD, or PDA) + one of the following: (3)

all forms of Cyanotic HD are UNCOMMON
severe PS
elevated pulmary vascular resistance
tricuspid stenosis
What is the most iportant clinical sequelae of chronic cyanosis?
polycythemia

due to systemic hypoxia (stimulates EPO)
What is Eisenmenger's Physiology?
a reversed PDA, VSD, or ASD
What age is does shunt reversal occur in?
less than 6 months
What has to occur in order for Eisenmenger's Physiology?
pulmonary vascular resistance exceeds systemic resistance
Tetralogy of Fallot is an uncommon malformation consisting of (4):
pulmonic stenosis (MURMUR)
VSD
override of the aorta over the VSD
RV hypertrophy

*clinical signs are related to hypoxemia and polycythemia
RA enlargement will show a bulge from __--__ on a VD/DV view.
9-11 (right cranial heart border)
___ may cause dorsal deviation of the trachea on rads.
right atrial enlargement

*this is because elevation is cranial to the birfurcation (different from LA enlargement which is as or behind the carina)
What do these have in common?

Pulmonic stenosis
Heartworms
tricuspid insufficiency
tetralogy of fallot
R-->L PDA or VSD
Cardiomyopathy
chronic pulmonary disease
can cause Right heart enlargement
You look at rads and notice an enlarged heart. There is a bulge from 2-3. What is this likely to be?
Left Auricle
What heart diseases are associated with Left Heart enlargement?
Mitral Valve insufficiency
PDA
Aortic Stenosis
Cardiomyopathy
VSD
You are examining rads of a dog with a heart murmur. You see a bulge at 1-2. What is this likely to be?
Pulmonary trunk enlargement
aortic stenosis results in a ___ (location) dilitation of the ascending aorta. This shows up on Rads as a bulge/widening of the aorta from ____ -____.
post-stenotic
11-1
What are the differentials for a giant globoid heart on rads?
pericardial effusion
peritoneal-pericardial diaphragmatic hernia
biventricular enlargement
CARDIOMEGALY!
Why should increased sernal contact NOT be used as a criterion for feline right heart enlargement?
it may occur in normal geriatric cats and can be associated with LA and LV enlargement
what is the difference between concentric enlargement and eccentric enlargement on radiographs?
concentric-- maintains normal apex

eccentric-- rounded apex
in the cat LA enlargement may take on the appearance of ___ (lat) or ___ (VD) if the LV is not dilated.
ice cream cone (lat)

valentine's heart (VD)
What Explain the vertebral heart scale method.
measure the heart from the ventral border of the LEFT mainstem bronchus to the most most ventral point of the APEX

+

fattest girth of the heart (upper 1/3)

=

overall size

(canine- 9.7 +/- 0.5, feline- 7.5 +/- 0.3)
What drugs would be good to use for animal restraint during a cardiac ultrasound?
opioids (butorphanol, buprenophine, hydromorphone)
acepromazine (dogs)
benzodiazepines

p 109 notes
The velocity of sound is a function of density and elastic properties of the transmitting medium. In soft tissues and blood this is about __ m/s.
1540 m/s
explain the relationship of the following transducer properties

resolution: frequency
resolution: penetration
resolution increases as frequency increases

resolution decreases as penetration increases
___ is the abiliy of some materials o generate an electric field or electric potential in response to applied mechanical stress.
piezoelectricity

*how the crystals in the transducer tip work
how should the beam be oriented to the interface in order to increase the received reflected sound waves?
perpendicular

*except for Doppler velocity interrogations of blood flow-- must be parallel
___ is a measure of contractility. It is obtained by (LV end diastolic width- LV end systolic width)/ LV end diastolic width.
Fractional shortening
the transducer must be ___ to blood flow in order to obtain accurate measurements of velocity.
PARALLEL (angle should be less than 20)

*cosine 0 = 1 vs cosine 90 = 0
Continuous wave doppler is different from pulsed wave doppler how?
continuous: high velocity BF-- exact site of sampling is unknown

pulsed: samples blood velocity at a specific location (does not work for high velocities)
What is Bernoulli's equation?
delta P = 4(Vsquared)

pressure gradient = 4 times velocity squared

*used to predict a pressure gradient across a valve/stenotic region/ VSD
_____ is required to characterize cardiac disease in cats.
echochardiograpic evaluation
T/F: ALL cases of Congenital heart disease require an echocardiogram and Doppler.
true


p 129
The ____ propogates as a wave of depolarization through the conduction system and myocardium.
action potential

*the wave is the electriccal signal that triggers myocardial contraction
What information does an ECG provid?
heart rate
rhythym
cardiac size (hypertrophy)

mean vector of ventricular or atrial activation (direction) aka Mean electrical axis
What two variables of the ECG can be controlled by th operator?
paper speed
sensitivity (units of the Y axis)
What general direction does cardiac contraction move in?
cranial to caudal
right to left
dorsal to ventral
Setting up leads allow for the generation of multiple lines of ECG to read. Waht is the significance of this?
allows for different vantage points fromw hic to view the electrical activity of the heart.
____ and ___ are superior to the ECG as a means of assessing heart size.
echo and rads
How is the p-wave different for LA and RA enlargement?
RA-- prolonged p wave

LA-- increased amplitude of p wave
What do small QRS complexes mean in a dog? in a cat?
dog-- pleural or pericardial effusion, obesity

cat-- QRS normally small
What is electrical alternans?
alternating QRS size

* assocated with pericardial effusion
What can you tell from the width of a QRS?
narrow: supraventricular origin

wide: ventricular origin (or intraventricular conduction delay-- uncommon)
Rhythm analysis:
(3) important steps/questions
1. determine HR
2. is the rhythm regular or not
3. association b/t atrial and ventricular activity?
T/F: ALL real QRS complexes MUST have an associated T wave.
True
T/F: T waves can be positive, negative, or biphasic in dogs.
true
Whats the range for sinus tachycardia?
160+ for dogs
240+ for cats
Whats the range for sinus bradycardia?
below 70 in dogs
below 160 in cats
Premature Supraventricular Complexes result in an abrupt decrease in the ___ .
RR interval

*p wave is usually superimposed on or even obscured by the T wave
Premature supraventricular tachycardias differ from Sinus tachycardia and atrial fib because they arise from ___ which makes them very regular in pattern.
a single supraventricular focus

*they are usually rapid (>240bpm)
What is the shining characteristic of atrial fib?
NO P WAVES!!!!
rapid
irregular
_____ must precede the development of AF.
marked atrial enlargement

*this is b.c a critical mass of atrial myocardium is required to support the arrhythmia
Premature Ventricular Complexes occur early relative to the previous RR. What does the QRS look like?
WIDE and bizarre

dump= lub dub

so its like dump dump dump WHOMP dump dump WHOMP dump dump.

(where as Supraventricular Premature complexes would be like dumpdump dumpdump dumpdump)
Ventricular tachycardia is defined as more than ____ ectopic ventricular complexes in a row.
3
Ventricular fibrillation is ____ rhythm.
pulseless
ventricular fib is a pulseless rhythm that is lethal without prompt _____
DC cardioversion

(direct-current-- IE: the toaster!)
T/F: Vtac can degenerate to Vfib.
true
____ is an important cause of sudden arrhythmic death and is the final cardiac rhythm of many dying patients.
Ventricular Fib
Name some "extracardiac diseases" that might cause ventricular arrhythmias.
GDV
road trauma
splenic disease
neurologic disease
sepsis

electrolyte, autonomic, pH imbalances
Ventricular Arrhythmias are relatively (fast/slow).
slow
Describe a second degree AV block and causes.
failure of 1 or more atrial depolarizations to conduct to the ventricles

d/t:
high vagal tone (will resolve with atropine admin)
diseased AV node (atropine has no effect
T/F: first degree AV block has NO effect on Cardiac output.
True

*may hear S4 (gallop)
____ is an important cause of syncope-- many patients can be effectively treated with the implantation of a permanent electronic pacemaker.
3rd degree AV block
What breeds are predisposed to Sick Sinus Syndrome?
older, smaller breeds
miniature schnauzers
cockers
terriers
How do you differ between physiologic sinus bradycardia and pathological sinus node?
atropine will resolve physiologic forms

*diverse appearance on ECG
T/F: Hyperkalemia will cause a tachycardia.
False

bradycardia
*no p-wave
*wide QRS
What causes syncope? ie: define the process not the diseases.
transient decrease in cerebral perfusion pressure caused by either a decrease in cardiac output or an inappropriate degree of peripheral vasodilation
what arrhythmogenic diseases cause syncope?
rapid VTACH
rapid SVT
high grade 2-3 AV block
What structural cardiac diseases cause syncope? (think about limiting Cardiac output)
aortic stenosis
pulmonic stenosis
pulmonary hypertension
mitral valve regurgitation
Whats in the minimum database of syncope diagnosis?
CBC
chem
UA
resting EKG
What are the Determinants of Cardiac output according to Dr. Abbot?
Heart rate
Preload
Afterload
Contractility
____ is a potential consequence of practically ANY cardiac disease.
Heart failure
What is the anatomical classificaiton of heart disease?
pericardial disease
myocardial disease
endocardial disease
disease of the conduction system
what is the pathophysiologic classifcation of heart disease?
volume overload
pressure overload
contractile dysfunction
diastolic dysfunction
arrhytmias
high CO states
T/F: a cat with a cough likely has CHF.
False.

*cats with heart disease rarely cough
____ is the difference between systolic and diastolic pressure.
pulse pressure
Where can you measure the Central Venous Pressure non-invasively?
external jugular... should pulsate 5-8cm (1/3) above the thoracic inlet ie: the level of the RA
What occurs during S1?
closure of the AV valves

LA-> mitral-> LV

RA-> tricuspid -> RV

(also begins atrial diastole)
What occurs during S2?
closure of the semilunar valves

L- aortic
R- pulmonic

(also begins ventricular diastole: remember T wave follow QRS which is S2)
What occurs during the p-wave?
S4: atrial systole/ late ventricular diastole
What is the difference between a gallop and a click?
gallop is an actual heart sound-- S4-- that is generally not audible

click is the splitting of S1 into 2 audible components (generally occurs so close that we cannot differentiate)
___ is a prolonged series of vibrations that originate from the cardiovascular system and is audible with a stethoscope.
Murmur
What are the 3 determinants of blood flow character?
velocity-- acceleration explains almost all murmurs

viscosity-- anemia may explain murmurs when HCT<17

vessel diameter
How are murmurs characterized?
intensity, location, timing
Explain the grading system for Murmur intensity.... generally.
1-2 soft, require expert
3,4 - intermediate, loud
5,6- precordial thrill
Significant weight loss is common in ___ with CHF but not ___.
weight loss is common in dogs

not cats
___ is often the first clinical sign of heart disease in cats.
Dyspnea
Mid-systolic clicks are common in what breed?
Cavalier King Charles Spaniel
diminished heart sounds may be appreciated with ____ where as diminished lung sounds may be a result of ___, ___, and ___.
heart: pericardial effusions

lung: pleural effusion, pneumothorax, atelectasis, masses
Louder than norma lung sounds are indicative of ___.
pulmonary edema
What heart disease are males more predisposed to than females?
Dilated cardiomyopathy
What breeds are predisposed to dilateive cardiomyopathy?
Dobies, Boxers

giants: Danes, Irish Wolfhounds, Newfies, Borzois...
what breeds tend to get 3rd degree AV block?
labrador retrievers
chow chows
What diagnostic test would you do to determine why a patient is coughing?
Rads
What diagnostic test would you do to determine why a patient has an irregular heart beat?
ECG
What diagnostic test would you do to determine why a patien has a murmur?
Echo
What diagnostic test would you do to determine why a patient has pleural effusion?
echo, cytology, minimum.
What is Holter monitoring?
24 hour ambulatory ECG monitoring
What information can an echo provide?
cardiac anatomy and function

diastolic and sytolic pulmonary arterial pressure in the presence of pulmonic and tricuspid valve insufficiency, respectively
What is Central venous pressure? where is is measured?
CVP is a reflecction of RA pressure and therefore RV EDP.

it is measured in the great veins just before they enter the RA
What cardiac leakage biomarkers show up on a chem profile of a cardiac disease patient?
cardiac troponin I
cardiac troponin T
creatine kinase isoenzyme MB

functional biomarkers include: brain natriuretic peptide, atrial natriuretic peptide
___ and ___ are myofibrillar proteins in the cardiac muscle cells that regulate the calcium mediated action between actin and myosin filaments in cardiac muscle.
Cardiac troponin I and T
___ and ___ generally oppose the physiologic action of the renin-angiotensin-aldosterone system.
atrial natriuretic peptide
brain natriuretic peptide