Cardio Development I - Ccs

Front 1

Transverse Precardial Sinus

Back 1

space behind great vessels - aorta pulmonary trunk

Front 2

Dextrocardia

Back 2

loops to the left instead of the right - most associated with situs inversus (general reversal of many organs)

Front 3

Shift to the right

Back 3

due to left to right shunts of blood occur in venous system

Front 4

Common Atrium (Cor Triloculare Biventriculare)

Back 4

neither septum primum nor septim secundum form; always associated with serious defects elsewhere in the heart; serious fatal condition

Front 5

Ostium Secundum Defect

Back 5

cause by excessive resorption of septum primumm, septum secundum or both; F/M 3:1; some blood passes from left atrium to right; over long period can be tolerated; ultimately causes right atrial hypertrophy, increased blood flow to lungs and pulmonary hypertension

Front 6

Ventricular Septal Defects (VSD)

Back 6

-most common of all congenital heart malformations (25%)
-1:900 births
-most membranous portion of septum; associated w/ partitioning of conotruncal region
-large defect associated with left to right shunting of blood
-surgical repair
-muscular VSD's usually small defects often close after birth "Swiss Cheese Defect"

Front 7

Persistent Truncus Arteriosus

Back 7

-insufficient neural crest cell migration, only partial AP septum
-results only one large vessel, recieve blood from both L & R ventricles
-usually associated with membranous VSD

Front 8

Transposition of the great vessels

Back 8

-1:2000 live births
-septum grows almost straight down the truncus
-result in aorta being transported to RV and pulmonary to LV
-systemic and pulmonary completely seperated
-not immediately fatal, ductus ateriosus or foramen ovale
-cyanosis
-leading cause of death in infants w/ cyanotic heart disease

Front 9

Tetralogy of Fallot

Back 9

-abnormal AP septum
1. Pulmonary Stenosis
2. Overriding Aorta
3. VSD
4. Right Ventricular Hypertrophy