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296 Cards in this Set

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Most striking PE feature of pericarditis

Pericardial friction rub

O

ECG finding of pericarditis

Diffuse ST-elevation in all leads, except AVR, AVF, V1

Hamman's sign

Pericardial friction rub

Bread and butter pericarditis: type of pericarditis

Fibrinous

Most common type pericarditis (though not in the Philippines)

Fibrinous

Five types of acute pericarditis

Serous


Fibrinous/serofibrinous


Purulent/suppurative


Hemorrhagic


Caseous


Pericarditis type due to surgery

Hemorrhagic pericarditis

Pericarditis type due to TB

Caseous Pericarditis

In subxiphoid approach to pericardiocentesis, how is the needle inserted

Left of the xiohoid process, upward and backward direction in a 45 degree angle to the skin

Which structure is targeted in pericardiocentesis

Cardiac notch

Why is the cardiac notch the ideal site for pericardiocentesis

It is devoid of pleura. To prevent pneumothorax and damage to the lungs, care must be taken not to pierce the pleura.

In the infrasternal angle approach to pericardiocentesis, the needle is pierced through where

5th or 6th ICS near sternum, with needle towards left shoulder

Most common cause of myocarditis

Coxsackievirus B

Inflammation of myocardium

Myocarditis

Two types of chronic pericarditis


Adhesive mediastinopericarditis


Constrictive pericarditis

Type of acute pericarditis that may lead to constrictive pericarditis

Purulent/supurative pericarditis

Histopathological findings of myocarditis

Interstitial inflammatory infiltrates with focal myocyte necrosis

Murmur of PDA

Continuous harsh machinery murmur

Obstruction in descending aorta just opposite the ligamentum arteriosum

Coarcatation of the aorta

Two types of coarctation of the aorta

Infantile (preductal)


Adult (postductal)

Greatest risk factor for congenital heart disease

CHD in a parent or preceding sibling

Infantile coarctation of the aorta: pre or post ductal

Preductal

Post-ductal: adult or infantile coarctation of aorta

Adult

Most common type of Coarctation of aorta

Infantile (preductal)

Lower body cyanosis: Infantile or Adult coarctation of aorta

Infantile

Most common genetic risk of Congenital Heart Disease

Down syndrome

Snowman appearance in CXR is in this disease

TAPVR

ASD murmurs

Mid systolic murmur of upper sternal border


Fixed widely split S2

Most common congenital heart disease associated with congenital rubella syndrome

PDA

Cyanosis: R to L or L to right shunting

R to L

Most common cyanotic congenital heart disease

Tetralogy of fallot

Components of TOF

Pulmonic stenosis


R ventricular hylertrophy


Overriding the VSD by the aorta


Ventricular septal defect

L to R shunting: cyanotic or acyanotic

Acyanotic

VSD most common in: adults or children

Children

Most common congenital heart disease seen in adults

ASD

Xray finding of TOF

Boot shaped heart

Boot shaped heart of TOF is due to which of its components

RVH

Definitive management for TOF

Blaylock-Taussig Shunt

What disease:


Pulmonic stenosis


R ventricular hypertrophy


Overriding the VSD by the aorta


Ventricular septal defect

TOF

Anomalous connections by pulmonary veins to systemic veins

TAVR

TET spells of TOF occurs when

Crying or feeding

Severity of TOF cyanosis depends on what

Pulmonic stenosis

Components of Ebstein's anomaly

Tricuspid valve displacement


Artrialized R ventricle


ASD

CXR finding of Ebstein's anomaly

Wall to wall/ box-shaped heart

How to stop tet spells

Squatting


Propanolol

Why does squatting reverse cyanosis in tet spells

Increases TPR causing reversal of R to L shunt

Drug that may cause Ebstein's anomaly

Lithium

Egg shaped cardiac silhouette is in what heart disease

TGA

Box shaped heart xray finding is in what disease

Ebstein's anomaly

What disease:


Tricuspid valve displacement Artrialized R ventricle


ASD

Ebstein's anomaly

Disease: switching of aorta and pulmonary arteries

TGA

Most common variant of TAPVR

Supracardiac

Four types of TAPVR

Supracardiac


Infradiaphragmatic


Cardiac


Mixed

CXR finding of TAPVR

Figure of 8/ Snowman appearance

Most common type of ASD

Secundum

Types of ASD

Primum


Secundum


Sinus venosus

Most common ASD in Down sydrome

Primum

Types of VSD

Membranous


Infundibular


Ventricular septum

Most common type of VSD

Membranous

Most common heart disease in Down Syndrome

ECD

Multiple VSD appearance

Swiss-cheese septum

Upper extremity hypertension: Infantile or adult coarctation

Adult

Rib notching: Infantile or adult coarctation

Adult

Genetic disorder associated with Coarctation of Aorta

Turner's syndrome

Congenital heart disease most common in Noonan syndrome

Pulmomary stenosis

Associated with Turner's syndrome: infantile or adult coarctation

Infantile

CXR finding of coarctation of aorta

3-sign


Rib notching

Type of MI due to a thrombus

STEMI

Type of MI due to atherosclerosis

NSTEMI

Most common complication of MI

cardiac arrhythmia

Most common cause of in-hospital death in MI

Cardiac arrythmia

ECG leads of inferior wall

II, III, avF

Tuti sa floor

ECG leads of septal wall

V1-V2

Septal is ThiN

ECG leads of anterior wall

V3-V4

MaR boobies in front

ECG leads of lateral wall

V5-V6

Love Bundles on lateral

ECG leads of right ventricular wall

V3R-V4R

Wall corresponding to ECG leads V1-V2

Septal wall

Wall corresponding to ECG leads II, III, avF

Inferior wall

Tuti sa floor

Wall corresponding to ECG leads V3-V4

Anterior wall

1993 = Mar = boobies

Wall corresponding to ECG leads V3R to V4R

Right ventricular wall

Wall corresponding to ECG leads V5-V6

Lateral wall

The ductus arteriosus is derived from which aortic arch

6th

Truncus arteriosus is often seen in patients with DiGeorge syndrome; This association suggests a common embryologic defect involving early development of which embryonic cells

Neural crest cells

Three types of aortic stenosis

Subvalvular


Valvular


Supravalvular

A patent ductus arteriosus connects which two vessels

Pulmonary artery and descending thoracic aorta

PDA: usually proximal or distal to the left subclavian artery

Distal

Swiss Cheese septum occurs in which type of VSD

Muscular

Three types of angina pectoris

Stable (typical) angina


Prinzmetal variant


Unstable (crescendo) angina

Most common form of angina

Stable (typical) angina

Angina that may be imminent MI

Unstable (crescendo) angina

Angina caused by coronary artery spasm

Prinzmetal variant


(May also be unstable angina)

Angina at rest/unrelated to physical activity

Unstable (crescendo) angina


Prinzmetal variant

Angina associated with activity, relieved by rest

Stable angina

Significant luminal narrowing due atherosclerosis that produces anginal symptoms

75%

Angina not relieved by nitrates

Unstable (crescendo) angina

Drug of choice for Prinzmetal angina

Calcium channel blockers

Major risk factors for MI

Hypertension


Smoking


Diabetes


Hyperlipidemia

Point in women's life that they are most protected from MI

Reproductive years

Irreversible myocardial damage happens how long after an infarct

20-30 mins

The least perfused layer of the heart, most vulnerable to ischemia

Subendocardial zone

Three patterns of myocardial infaction

Transmural


Subendothelial


Multifocal microinfarction

Type of infarction pattern in cocaine users

Multifocal microinfarction

Type of infarction associated with ST elevation

Transmural

Type of ECG pattern associated with subendocardial infarction

NSTEMI

Blockage of which artery leads to infarction of the cardiac apex

LAD

Most commonly involved vessel in myocardial infarction

LAD>RCA

Most common cause of death in patients with PDA

Congestive heart failure

Treatment of choice for an infant with coarctation of the aorta

Resection with primary anastomosis

Most common location of coarctation of aorta

Distal to the left subclavian artery

Treatment of choice for recurrent COA (after surgical repair) in an preschool-aged child?

Balloon dilatation alone

Killips class III and class IV mortality rate

38% and 81%

Killips III description

pulmonary edema

Killips IV description

Cardiogenic shock

Neurodegenerative disease that presents with parkinsonism and autonomic dysfunction

Multiple systems atrophy (Shy Drager Syndrome)

Most common valvular abnormality

Calcific aortic stenosis

Most common cause of aortic stenosis

Calcification

The calcific process of aortic stenosis begins in which part of the valve

Valvular fibrosa

Substance that deposits in calcific aortic stenosis

Hydroxypatite (same calcium salt found in bone)

The four most common valvular abnormalities

Aortic stenosis


Aortic insufficiency/regurgitation


Mitral stenosis


Mitral insufficiency/regurgitation (prolapse)

Calcific deposits in the mitral valve develop in which part of the valve

Fibrous annulus

Characteristic mitral valve prolapse anatomic change

Interchordal ballooning (hooding) of mitral valve leaflets

Most common congenital heart valve defect

Bicuspid aortic valve

Most common valvular lesion causing syncope and angina in exercise

Aortic stenosis

Valve orifice narrowing in aortic stenosis that is of clinical importance

1 cm^2

Three cardinal symptoms of aortic stenosis

Exertional dyspnea


Angina pectoris


Syncope

Characteristic murmur of aortic stenosis

Ejection (mid) systolic murmur, loudest at second right ICS

Right sided murmurs increase during: inspiration or expiration

Inspiration

RIght, LEft

Cardiac murmurs that increase during expiration: right-sided or left-sided

Left-sided

Disease:


Ejection (mid) systolic murmur


Pulsus parvus et tardus


2nd ICS R

Aortic stenosis

Gold standard for diagnosis of valvular disease

Transthoracic echocardiography

Corrigan's pulse

Rapidly rising "water-hammer" pulse, which collapses suddenly as arterial pressure false rapidly during late systole and diastole

Quincke's pulse

Capillary pulsation, an alternate flushing and paling of the skin at the root of the nail while pressure is applied to the tip of the nail

Quincke's pulse and Corrigan's pulse are characteristic of which cardiac lesion

Aortic regurgitation/ insufficiency

Traube's sign

Booming "pistol-shot" sound heard over the femoral arteries

Duroziez's sign

To-and-fro murmur when femoral artery is lightly compressed with stethoscope

Watson's water hammer pulse seen in chronic severe aortic regurgitation

Corrigan's pulse

Capillary pulsation seen in chronic severe aortic insufficiency

Quincke's pulse

Pistol shot sound heard over the arteries in aortic regurgitation

Traube's sign

To-and-fro murmur heard when lightly compressing the femoral arteries in aortic insufficiency

Duroziez's sign

Disease:


Widened pulse pressure


Corrigan's pulse


Traube's sign


Duroziez's sign


Quincke's pulse



Aortic regurgitation

Characteristic murmur of chronic aortic regurgitation

High-pitched, blowing, decrescendo diastolic murmur, loudest at thrid ICS L sternal border

Most common cause of aortic regurgitation

Dilation of the ascending aorta, often secondary to hypertension or aging

Austin flint mumur

A soft, low-pitched rumbing mid to late diastolic murmur

Murmur frequently heard in isolated aortic regurgitation

Mid-systolic ejection murmur at base of heart, and along carotids

Three main murmurs of aortic regurgitation

High-pitched, blowing, decrescendo diastolic murmur


Mid-systolic ejection murmur


Austin flint murmur

A soft, low-pitched rumbling mid-to-late diastolic murmur

Austin Flint murmur

Most common infectious cause of aortic regurgitation

Infective endocarditis

Mueller's sign

Systolic pulsation of the uvula

Systolic pulsation of the uvula seen in aortic regurgitation

Mueller's sign

Hill's sign

BP in lower extremity (popliteal pulse) is greater than BP in upper extremity (brachial pulse) by 30 mmHg

Demusset's sign

Headbobbing with diastole

Headbobbing in aortic regurgitation

Demusset's sign

Most common cause of mitral stenosis

Rheumatic heart disease

Auscultatory triad in mitral stenosis

Opening snap


Diastolic rumble


Increased S1


- best heard at apex

Most common cause of mitral valve insufficiency

Myxomatous degeneration (mitral valve prolapse)

Disease:


Rust colored sputum


Atrial fibrilation


Dysphagia for solids


Fish mouth opening


Right sided failure

Mitral stenosis

Barlow's syndrome other name

Mitral valve prolapse

Billowing mitral leaflet syndrome

Mitral valve prolapse

Mid systolic click in MVP is heard near S1 during these conditions

Anxiety


Standing


Valsalva

Mid systolic click in MVP during reclining and squatting is heard near: S1 or S2

S2

Anxiety, standing and valsalva: increased or decreased preload

Decreased

Mitral regurgitation is more common in: males or females

Males

MR

Mitral valve prolapse is most associated with which genetic disorders

Connective tissue disorders: Marfan's


Ehler-Danlos


Osteogenesis imperfects

Valvular lesion most associated with Marfans

Mitral valve prolapse

Most common cause of acquired heart disease in developing countries

Rheumatic heart disease

Major criteria for rheumatic fever

JONES criteria


Joint pains


Carditis


Subcutaneous nodules


Erythema marginatum


Sydenham chorea

Pathophysiology of RHD

Molecular mimicry of M protein to myosin in the body causes antibody response against own tissues

Most common presentation of rheumatic fever

Polyarthritis

Most common cardiac symptom of rheumatic fever

Carditis

Human leukocyte antigens associated with susceptibility to rheumatic fever

HLA-DR7


HLA-DR4

Hallmark of rheumatic carditis

Valvular damage

Most commonly affected valve in rheumatic heart disease

Mitral valve

Manifestation in the Jones criteria that may still point to rheumatic fever in the absence of other manifestations

Syndenham's chorea

Most common serologic tests for diagnosis of rheumatic fever

ASO


anti-DNAse B

Drugs for secondary prophylaxis of RHD

Benzathine penicillin


Penicilin V


Erythromycin (for penicillin allergy)

Most common cause of infective endocarditis

Bacteria

Most common cause of acute infective endocarditis

S. aureus

Most common cause of subacute infective endocarditis

S. viridans

HACEK group bacteria

Haemophilus


Actinobacillus


Cardiobacterium


Eikanella


Kingella

HACEK is associated with which disease

Infective endocarditis

Most common pathogen in endocarditis in IV drug users

S. auerus

Most commonly affected cardiac valve in IV drug user

Tricuspid valve

Classic hallmark of infective endocarditis

Vegetations on heart valves

Most common pathogen in IE in valve prosthetics

S. epidermidis

Most common valves affected in IE

Aortic and mitral

Most consistent sign of IE

Fever

Diagnostic criteria for infective endocarditis

Modified Duke criteria



Jones criteria is diagnostic for which disease

Rheumatic fever

Modified Duke criteria is diagnostic for which disease

Infective endocarditis

Most common malignancy associated with marantic endocarditis

Small cell lung ca/ oat cell

Erythematous or hemorrhagic nontender macules on the palms or sole

Janeway lesions

Janeway lesions: more common in acute or subacute IE

Subacute

Osler's node: more common in acute or subacute IE

Acute

Tender subcutaneous nodules usually found on the distal digital pads

Osler's nodes

Retinal hemorrhages in eyes seen in IE

Roth spots

Most common classical peripheral manifestation of infective endocarditis

Petechiae

Irregular thickening induced by subendocardial lesions, exacerbated by regurgiant jets, usually in the left atrium

MacCallum plates

Freely mobile, evanescent nodules consiting of Aschoff bodies attached to the tendon sheaths near bony prominences

Subcutaneous nodules

Painless: Osler's nodes or subcutaneous nodules

Subcutaneous nodules

Osler's nodes: painful or painless

Painful

Foci of swollen eosinophillic collagen surrounded by T cells, plasma cells, Anitschow cells and giant cells

Aschoff bodies

Anitschow cells

Also caterpillar cells;


activated macrophages/histiocytes containing abundant cytoplasm, round nuclei with slender wavy ribbon of chromatin

MacCallum plaques

Irregular thickening of the subendocardium

Activated macrophages/histiocytes containing abundant cytoplasm, round nuclei with slender wavy ribbon of chromatin

Caterpillar cells/ Anitschow cells

Histologic hallmark of rheumatic activity

Aschoff bodies

Aschoff bodies

Foci of swollen eosinophilic collagen and inflammatory cells

Carcinoid heart disease most commonly involves which part of the heart

Endocardium,


Right sided valves

Most common cause of congestive heart failure

Ischemia

Most common cause of right-sided heart failure

Left-sided heart failure

Peripheral edema is more commonly seen in: left-sided right sided heart failure

Right-sided failure

Pulmonary hypertension is more commonly seen in: left-sided or right-sided failure

Left-sided failure

Pulmonary congestion is more commonly seen in: left or right-sided heart failure

Left-sided failure

Liver congestion is more commonly seen in: left or right-sided failure

Right-sided failure

Heart failure with reduced ejection fraction (HFrEF): systolic or diastolic failure

Systolic failure

Diastolic failure: reduced or preserved ejection fraction

Preserved ejection fraction

The most useful index of LV function

Ejection fraction

Aka pulmonary heart disease

Cor pulmonale

Acute cor pulmonale: RV dilatation or RV hypertrophy

RV dilatation

RV hypertrophy: acute or chronic cor pulmonale

Chronic

Most common symptom of cor pulmonale

Dyspnea

Carvallo's sign

Increase in intensity of holosystolic murmur of tricuspid regurgitation with inspiration

Tachycardia + hypertension in acute MI

James reflex

Bradycardia + hypotension in acute MI

Bezold-Jarisch reflex

Most sensitive and most specific test for myocardium damage

Trop I

Trop I peaks when

12 hrs

Most common arrythmia that causes mortality in out-of hospital setting

Ventricular fibrilation

Most common cause of heart transplant

Dilated (congestive) cardiomyopathy

Disease:


diminished myocardiac contractility,


impaired systolic pump function,


cardiac enlargement


dilatation of all 4 chambers

Dilated (congestive) cardiomyopathy

Most common form of cardiomyopathy

Dilated (congestive) cardiomyopathy

Histologic findings of dilated cardiomyopathy

Interstitial and perivascular fibrosis


Myocyte necrosis


Cellular infiltration

Most common etiology of dilated cardiomyopathy

Idiopathic

Second most common cause of dilated cardiomyopathy

Alcohol

Most common toxin associated with chronic dilated cardioyopathy

Alcohol

Acute cardiac rhythim and/or conduction disturbance associated with heavy ethanol consumption, no clinical evidence of heart disease

Holiday heart syndrome

Most common arrhythmia seen in Holiday Heart syndrome

Atrial fibrillation

Second most common arrhythmia seen in Holiday heart syndrome

Atrial flutter

Causes of atrial fibrilation

Ethanol


Valvular heart disease


Ischemic heart disease


Cardiomyopathy/coccaine


Thyroid disorders

EVICT

Most common symptom of holiday heart disease

Palpitations

Least common cardiomyopathy

Restrictive

Largest protein expressed in humans

Titin

TTN mutation is associated with which cardiac disease

Dilated cardiomyopathy

Most common manifestation of iron excess

Dilated cardiomyopathy

Most commonly affected part of the heart in takotsubo cardiomyopathy

Left ventricular apex

Most common cause of cadiomyopathy among drugs

Chemotherapeutic drugs

Cardioprotective drug given in chemotherapy

Dextrazoxane

Disease:


myocardial hypertrophy of interverntricular septum


abnormal diastolic filling


intermittent ventricular outflow obstruction


narrowed subaortic area

Hypertrophic cardiomyopathy

Common cause of sudden cardiac death in young athletes

Hypertrophic cardiomyopathy

Most common mutation in hypertrophic cardiomyopathy

cardiac beta-myosin heavy chain gene on chromosome 14

Disease: sudden death in children and young adults often during or after physical exertion

Hypertrophic cardiomyopathy

Hallmark chest findings in hypertrophic cardiomyopathy

Systolic murmur at the left sternal border and apex

Most common complaint in hypertrophic cardiomyopathy

Dyspnea

Treatment for hypertrophic cardiomyopathy

Beta blocker


Verapamil

Hallmark of restrictive cardiomyopathy

Abnormal diastolic function

Most prominent symptoms of restrictive cardiomypathy

Exercise intolerance


Dyspnea

Most common cause of restrictive cardiomyopathy die to hemochromatosis

Beta-thalassemia

Apical ballooning syndrome

Takotsubo (stress) cardiomyopathy

Most common typs of pericardialeffusion

Serous

Most common cause of hemorrhagic pericarditis

Malignant neoplastic involvement of the pericardial space

Nonadherent epicardial plaque seen in healing acute pericardial lesions

Soldier's plaque

Disease: pericardial sac is obliterated and the parietal layer is tethered to mediastinal tissue

Adhesive mediastinopericarditis

Disorder:


Arrhythmogenic right ventricular cardiomyopathy


Hyperkeratosis of plantar palmar skin surfaces


mutations in gene for desmosome-associated protein plakoglobin

Naxos syndrome

Disease: RV failure


Rhythmic disturbances (Vtach or vfib)


Sudden death

Arrhythmogenic ventricular cardiomyopathy

Hypercontracting: DCM or HCM

HCM

most common cause of acquired heart disease in children in countries

rheumatic heart disease

component of cardiac valve cells to which m protein reacts

n-acetylglucosamine

pathognomonic cells for rheumatic fever

Anitschkow cells

Anitschow cells are what type of cells

histiocytes

histologic marker of severe carditis in rheumatic heart disease

Aschoff bodies

disease:


maccallum plaques


anitschkow cells


Aschoff bodies

rheumatic heart disease



human leukocyte antigen seen in both rheumatic heart disease and rheumatoid arthritis

HLA-4

Drug of choice for prophylaxis of rheumatic fever

penicillin

choice drug for treatment of arthritis, arthralgias, fever in rheumatic fever

nsaids


salicylates

best antibiotic for secondary prophylaxis of rheumatic heart disease

benzathine penicillin

Pathogen seen in endocarditis that is also seen in colorectal cancer

streptococcus bovis

management for acute endocarditis

Surgery

management for subacute endocarditis

Antibiotics

single positive blood culture needed for this organism to diagnose infective endocarditis

coxiella burnetii

the only rickettsia bacteria that can be transmitted through fomites

coxiella burnetii

roth spots are seen in which organ

Retina

roth spots are diagnostic of which disease

infective endocarditis

disease:


Osler's nodes


roth spots


rheumatoid factor


janeway lesion

infective endocarditis

most common blood abnormality in infective endocarditis

anemia

second most common manifestation of endocarditis

heart murmur

type of endocarditis with fever greater than 39.4 degrees

acute endocarditis

empirical therapy for acute and localities in an injection drug users

gentamicin + vancomycin

empirical therapy for blood culture negative subacute nve

gentamicin + ampicillin sulbactam or ceftriaxone

drug for penicillin susceptible streptococci in endocarditis

penicillin ceftriaxone or vancomycin

Antibiotic treatment for hacek organisms in infective endocarditis

ceftriaxone or ampicillin sulbactam

drug for coxiella burnetii endocarditis

doxycycline + hydroxychloroquine

drug for bartonella in infective endocarditis

doxycycline plus gentamicin

early marker of renal injury also considered a risk factor for renal disease progression and cardiovascular disease

urinary albumin /creatinine ratio

Ankle brachial index indicative of peripheral arterial disease

less than 0.9

peripheral arterial disease associated with excessive smoking

Buerger's disease

nonpharmacologic intervention that has the highest systolic blood pressure lowering effect hypertensive patients

dash diet (dietary approaches to stop hypertension)

sodium limitation in dash diet

1500 mg per day

dash diet decreases blood pressure by this amount in hypertensive patients

11 mm hg