Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
|
anticoagulents (blood thinners) |
though sometimes called blood thinners, anticoagulents do not actually thin blood; instead, they prevent clotting of blood. blood flows more smoothly > decreases BP > decreases afterload > increases SV> increases CO |
|
|
angiotensin-converting enzyme (ACE) inhibitors |
-expands blood vessels and decreases resistance by lowering angiotensin levels (which narrow blood vessels) -inhibits renin, which reduces Na+ uptake and fluid uptake in kidneys, decreasing BP - decreases BP > decreases afterload > increases SV> increases CO |
|
|
calcium channel blockers |
affects Ca+ movement into smooth muscle cells of blood vessels and dilates blood vessels - decreases BP > decreases afterload > increases SV> increases CO |
|
|
digitalis |
-originally derived from foxglove plant! -increases force of heart's contractions in weakened hearts -treat heart failure and irregular heart rhythms -inhibits Na/K ATPase, lessening the Na+ gradient needed to pump Ca+ out of cells; more Ca+ remains in cell to pump heart muscle -increased contractility> increased SV> increased CO |
|
|
diuretics |
-sometimes called "water pills" -increase kidney excretion of Na+ and water, reducing fluid in the body and decreasing blood pressure - decreases BP > decreases afterload > increases SV> increases CO |
|
|
alpha-adrenergic blocking drugs |
-block alpha receptors in the autonomic nervous system; alpha receptors usually constrict blood vessels -inhibit action of norephinephrin, which increases HR -decreases BP > decreases afterload > increases SV> increases CO |
|
|
beta-blockers |
-beta blockers block K+ channels in both cardiac muscle cells and autorhythmic cells -in autorhythmic cells, K+ can't leave as quickly, so voltage of cells decreases less quickly (repolarizes less quickly), causing HR to decrease, decreasing CO -in cardiac muscle cells, K+ and Ca+ are linked, and K+ flows out of cell as Ca+ flows into cell. Since K+ flows out more slowly, Ca+ flows into cell more slowly; less Ca+ in cell causes decreased contractility, and decreased SV, decreased CO |
