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14 Cards in this Set
- Front
- Back
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What are the categories of the 2001 Bethesda system?
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Specimen type: conventional vs. LBP vs. other
Specimen adequacy: sat/unsat General Categorization: normal/abnormal & type Interpretation/result: specific result Results of ancillary testing: if applicable Automated review: if applicable Educational notes & suggestions: optional |
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What are the 2 categories for specimen adequacy?
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1. unable to be processed due to improper labeling, broken slides, or other reasons
2. able to be processed and evaluated but interpretation is limited due to lack of cellularity, obscurity by inflammation/blood, or air-drying. |
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What is the most common cause for unsatisfactory specimens in LBPs?
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lack of squamous cellularity
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What are 2 common causes for unsatisfactory specimens in conventionals?
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obscurity by blood/inflammation
and air-drying |
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Is the TZ component required for a slide to be fully satisfactory (according to Bethesda)?
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The Bethesda System does NOT require that TZ components be present on the slide for a fully satisfactory specimen.
Some labs have a QI (quality indicators) section of the report where TZ component absence may be listed |
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How many endocervical or metaplastic cells must be there to have TZ present?
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10, either in groups or isolated
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Should normal risk patients get a repeat pap if TZ is not sampled?
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No, it is okay for them to just get another routine pap in 1 year because they are normal risk patients.
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Describe normal superficial squamous cells
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-most mature
-abundant, polygonal cytoplasm -dense/glassy cytoplasm -stains eosinophilic usually but can stain cyanophilic depending on amt of keratin in cytoskeleton -keratin that is most mature stains orange -pyknotic nuclei/small nuclei |
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Describe normal intermediate squamous cells
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-found just below superficial cells in normal, fully mature sq. epithelium
-polygonal cytoplasm with rounded edges -almost always cyanophilic -dense to slightly granular texture -35 micrometers for nuclear size -vesicular chromatin |
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Describe normal parabasal squamous cells
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-least mature
-only identified in pap tests from women with immature epithelia -smaller, with higher nc ratios -round to oval cytoplasm -dense/granular cytoplasm -stains cyanophilic -larger nuclei than intermediate -may present in groups or singly -vesicular chromatin |
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The transformation zone consists of the area just above the ___________ squamous epithelium
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exocervical
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Describe squamous metaplastic cells
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cells in the process of maturing from reserve cells to mature intermediate/superficial squamous cells.
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what are reserve cells?
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the least differentiated squamous precursor found at the very base of the normal squamous epithelium, just above the basement membrane
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describe normal squamous metaplastic cells
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-round/oval, dense cytoplasm
-cyanophilic -small cytoplasmic vacuoles or granularity -higher nc ration that intermed. -larger nuclei than intermed. -spider cells -cookie cutter/cobblestone |
