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6 Cards in this Set
- Front
- Back
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Where is it mainly found? What does it cause? |
-Intervertebral discs -ID degeneration |
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How does it occur? |
-In all breeds but with big differences between chondrodystrophic dogs & nonchondrodystrophic dogs |
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What is an example of a chondrodystrophic dog? What happens in CHONDRODYSTROPHIC dogs? |
-Dachshund -They have fibroblast growth factor 4 which affects their spine length & leg curvature -proteoglycan content in chondrodystrophic dogs is less than nonchondrodystrophic dogs -chondrocyte proliferation within the nucleus pulpous (core of ID) leads to replacement of original structure with new chondroid structure |
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More info on chondrodystrophic dogs... |
-dogs with this disease show a decrease in water & glycosaminoglycan content & increase in collagen -mineralised ID in chon dogs are prone to hansen type l herniations - mainly dogs 3-7yrs -sudden compression of spinal cord & nerves causes acute pain, paresis or paralysis |
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What happens in NONCHONDRODYSTROPHIC dogs? |
-normal mucoid nucleus pulpous which persists until middle age & rarely mineralises -breeds are more likely to experience type ll herniations -develop slowly -Damage to spinal cord or peripheral nerve roots is less than in type l herniations; clinical signs are milder |
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nonchondrodystrophic continued... |
-most herniations occur through the dorsal or dorsolateral regions of the annulus; that surround the nucleus pulpous -dorsal herniation of disc material in spinal canal is most common cause of paresis or paralysis -ventral herniation may predispose to spondylosis -disc protrusions occur where the spine is most mobile |
