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12 Cards in this Set

  • Front
  • Back
local and systemic signs and symptoms associated with common cancers
Pain is most common
General:
Weight loss, fatigue, anorexia
Localized vs distant
May be obscured by concomitant disease
Local Signs and Symptoms of cancer
Pain
Compression, obstruction, destruction of nerves
-Mass
-Bleeding - tumor erosion of blood vessels
pain, change in stool diameter, vomiting
Colon cancer Local Signs and Symptoms
CNS effects due to primary or metastatic tumor
-Brain
Headache, visual disturbances, seizures, confusion, altered gait, projectile vomiting
-Spinal cord
Back pain, altered gait, paralysis
Anorexia -Cachexia
A Systemic Manifestation
Observed with many common solid tumors
-does not always correlate with decreased food intake
Both fat and skeletal muscle loss
Decreased lean body mass
-Not reversed with feeding unless cancer is effectively treated
True or false.Fatigue of cancer is not relieved by sleep or resting
True
Systemic Manifestations of cancer
Fatigue
Anorexia -Cachexia
Sleep Disorders
Anemia
Paraneoplastic Syndromes
Syndrome of Inappropriate Antidiuretic Secretion (SIADH)
Characterized by hyponatremia with hypo-osmolality, elevated renal excretion of sodium and urine osmolality > plasma osmolality
Normal volume status
-Most commonly seen in small cell lung cancer
Ectopic ACTH production (or ACTH-like substances)
-Small cell lung cancer, carcinoid tumors, other lung cancers, pancreatic, others
-Truncal obesity, purple striae, hypertension, fatigue, moon face, glucose intolerance, edema, osteoporosis
increased risk of venous thrombosis due to hypercoagulable state
Thromboembolic Disorders
A Paraneoplastic Syndromes which is Common cause of death in patients with cancer
Thromboembolic Disorders
Weakness in limbs
Lambert-Easton Myasthenic Syndrome: a type of Paraneoplastic Syndrome
-observed in SCLC