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5 Cards in this Set
- Front
- Back
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5FRU (pyrimidine analog)
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-disrupts metabolic process
-solid and GI tumors -metallic taste -interacts with diuretics -oral/GI ulcers -hand/foot syndrome -cardiac events in first 72 hours -crosses blood brain barrier |
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Mercatopurine (purine analog)
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-oral
-disrupts metabolic processes -hepatic dysfunction -> jaundice -allopurinol increases hepatic dysfunction |
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Adriamycin (anti-tumor antibiotic)
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-VESICANT
-injures cell DNA -IV -never used for infection -EKG and MUGA before treatment -hepatotoxic -interacts with Digoxin, Heparin, and __barbitals |
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Actinomycin D (anti-tumor antibiotic)
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-GI toxic
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Oncovin (vinca alkaloid)
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-VESICANT (hyaluronidase is antidote)
-NO BONE MARROW SUPPRESSION (good combo tx drug) -blocks mitosis -peripheral neuropathy -constipation -light sensitive -interacts with Digoxin |
