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6 Cards in this Set
- Front
- Back
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Cytoxan (alkylating agent)
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-most widely used
-kills cells -antidiuresis (>2L of fluid/day) -heomorrhagic cystitis -alopecia -nadir at 2 weeks |
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Leukeran (alkylating agent)
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-safest
-oral -hepatotoxic |
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Gliadel (alkylating agent)
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-burns with administration
-bone marrow suppression 6 weeks after tx -pulmonary fibrosis -crosses blood brain barrier |
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Platinol (platinum compound)
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-solid tumors
-nephrotoxic (treated with amifostiine) -ototoxic -hydrate before tx and FF -peripheral neuropathy |
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Methotrexate (folic acid analog)
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-disrupts metabolic process
-GI toxic -nephrotoxic -wait 6 mos after tx to get pregnant -pulmonary side effects |
