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17 Cards in this Set

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Cell proliferation that remains confined to its original location. Can be surgically removed.
Benign Tumor
Cell proliferation that can invade surrounding tissue and spread throughout the body via circulatory or lymphatic systems.
Resistant to localized treatment.
Malignant Tumor
Cancer of the epithelial cells.
Most common human cancer.
Carcinoma
Solid tumor of connective tissue.
Rare in humans.
Sarcoma
Cancer of blood forming cells
Leukemia
Cancer of the cells of the immune system (B-Lymphocytes)
Lymphoma
Most lethal type of cancer
Lung Cancer
Most common types of cancer
Prostate
Breast
Lung
Colon/Rectal
The development of tumors initiates from ______ that begins to proliferate abnormally.
A single cell
Tumors become more and more aggressive over time due to ______
Clonal Selection
Genes capable of inducing cell transformation
Oncogenes
The source of retroviral oncogenes
Proto-oncogenes
Abnormally expressed proto-oncogenes or mutated forms of proto-oncogenes
Oncogenes
rasH, rasK, rasN
Examples of human oncogense
ras oncogenes are produced from their proto-oncogenes by ______
Point Mutations resulting in single amino acid substitution @ critical points
The mutations in the ras oncogenes maintain the ras proteins in the _____ GTP-bound configuraton
ACTIVE
Some oncogenes are produced by abnormalities in chromosome structure including
Translocation
Duplications
Deletions