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17 Cards in this Set
- Front
- Back
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Cell proliferation that remains confined to its original location. Can be surgically removed.
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Benign Tumor
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Cell proliferation that can invade surrounding tissue and spread throughout the body via circulatory or lymphatic systems.
Resistant to localized treatment. |
Malignant Tumor
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Cancer of the epithelial cells.
Most common human cancer. |
Carcinoma
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Solid tumor of connective tissue.
Rare in humans. |
Sarcoma
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Cancer of blood forming cells
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Leukemia
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Cancer of the cells of the immune system (B-Lymphocytes)
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Lymphoma
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Most lethal type of cancer
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Lung Cancer
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Most common types of cancer
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Prostate
Breast Lung Colon/Rectal |
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The development of tumors initiates from ______ that begins to proliferate abnormally.
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A single cell
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Tumors become more and more aggressive over time due to ______
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Clonal Selection
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Genes capable of inducing cell transformation
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Oncogenes
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The source of retroviral oncogenes
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Proto-oncogenes
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Abnormally expressed proto-oncogenes or mutated forms of proto-oncogenes
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Oncogenes
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rasH, rasK, rasN
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Examples of human oncogense
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ras oncogenes are produced from their proto-oncogenes by ______
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Point Mutations resulting in single amino acid substitution @ critical points
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The mutations in the ras oncogenes maintain the ras proteins in the _____ GTP-bound configuraton
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ACTIVE
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Some oncogenes are produced by abnormalities in chromosome structure including
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Translocation
Duplications Deletions |
