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52 Cards in this Set

  • Front
  • Back

Chromatin

- building material of chromosomes
- complex of DNA and proteins
Chromosomes

- consist of one very long, linear DNA molecules with many protiens

Duplicated chromosome

- consists of two sister chromatids connected by sister chromatid cohesion
- each contains a copy of the DNA molecule

Chromatid
- sister chromatids: joined copies of the original chromosome
Centrosome

- subcellular region containing material that functions thorough the cell cycle to organize the cell's microtubules

Spindle Pole
where microtubules connect and extend from
Kinetochore

- a structure of proteins associated with specific sections of chromosomal DNA at each centromere
- some spindle microtubules attach
- each sister chromatid has one

Chromatin Condensation (tight packing)
- begins during prophase when the chromosomes become visible
Chromosome Decondensation (unpacking)
- during telophase when chromosomes become less condensed
Prophase
Step 1 of mitosis
- chromosomes condense
- nucleoli disappear
- miotic spindle begins to form
Prometaphase
Step 2 of mitosis
- nuclear envelope fragments and microtubules extend from each pole
- some attach to one kinetochore on each chromosome
Metaphase
Step 3 of mitosis
- chromosomes convene at the metaphase plate
Anaphase
Step 4 of mitosis
- sister chromatids separate and move to opposite ends of the cell
- the cell elongates
Telophase
Step 5 of mitosis
- daughter nuclei form
- nucleoli reappear
- chromosomes decondense
Cytokenisis

in animals:
- a cleavage furrow forms

in plants:
- a cell plate forms to become a cell wall

Mitosis
- 10% of cell cycle
- used for growth, repair/regeneration
- occurs in somatic (body) cells
- produces daughter cells identical to the parent
Meiosis
- used for reproduction only
- produces daughter cells with 1/2 the number of chromosomes as the parent
M phase

miotic phase
- includes both mitosis and cytokinesis
- usually the shortest part of the cell cycle
- alternates with the much longer interphase (90% of cycle)

Interphase
- 90% of cell cycle
- the cell that is about to divide grows and copies its chromosomes in preparation for division
G1 Phase
First gap of interphase: longest part
- cell grows to functional size
- makes enzymes
- makes nucleotides (building materials)
S Phase
Synthesis of interphase
- chromosomes are copied (DNA synthesis)
G2 Phase
Second gap of interphase
- cell grows even more
- centrosome is duplicated (for microtubules)

Frequencies of mitosis

1) continuous -> skin, blood, GI tract cells (can re-enter cell cycle at G0)
2) based on need -> liver (can re-enter cell cycle at G0)
3) rare/never -> neurons, muscle cells (permanent G0 in an adult)
-- most human cells are in G0

person who credited with first recognizing that living cells cannot arise spontaneously

Rudolf Virchow

the function of the mitotic cell cycle is to produce daughter cells that

are genetically identical to the parent cell

the complex of DNA and protein that makes up a eukaroytic chromosome is properly called

chromatin

the region a chromosome holding the two double strands or replicated DNA together is called

centromere

the centime is a region in which

sister chromatids are attached to one another in prophase

how many maternal chromosomes are present in a somatic human cell not engaged in cell divsion

23

cytokinesis refers to

division on the cytoplasm

chromatids are

identical copies of each other if they are part of the same chromsome

DNA in cells double during which phase

g1 and g2 phases

during interphase the genetic material of a typical eukayortic cell is

dispersed in the nucleus as long strands of chromatin

DNA relpication occurs in

the s phase of interphase in both somatic and reproductive cells

if a somatic human cell in just about to divide it has

92 chormosomes

what does NOT occur during mitosis

replication of chromsomes

during what phase in the cell cycle would you find the most DNA per cell

G2

in telophase of mitosis, the mitotic spindle breaks down and the chromatin uncoils. this is essentially the opposite of what happens in

prophase

which of the following phases of mitosis is essentially the opposite of pro metaphase in terms of the nuclear enevelope

telophase

when to the centrosomes seperate

prophase

following cytokinesis in an animal cell, how many centrioles does each new daughter cell poseses

two

the phase of mitosis during which the chromosome move toward the separate poles of the cell is

anaphase

one even occurring during g prophase is

the beginning of the formation of a spindle appatatus

during which stage of the cell cyle do sister chromatids seperate

anaphase

in animal cell mitosis the cleavage furrow forms during which stage of the cell cyle

cytokensis

at which stage of mitosis are chromosomes lined up in the one plane in preparation for their separation to opposite poles of the cell

metaphase

you would know a dividing cell was a plant cell rather than an animal cell if you saw that

it had formed a cell plate

what process doe not occur in diving bacteria

mitosis

during binary fission in bacterium

the origins of replication move apart

when a cell in S phase is fused with a cell in G1

DNA synthesis begins immediacy in the original G1 nucleus

what would be unlikely to sees a human cell dividing

nerve cell

bio

chapter 12