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143 Cards in this Set

  • Front
  • Back
what are "hot spots"? what causes them?
pyotraumatic dermatitis

self trauma
what are some causes of the self trauma leading to hot spots?
FLEAS
anal sac problems
ear problems
irritants
T/F animals with light hair coats are predisposed to hot spots
FALSE

dense coats
T/F hot spots can pop up very quickly
true.
what's the best way to treat hot spots?
find/correct underlying cause
clip and clean
astringent
corticosteroids
oral pred for the itching
e-collar
when do you want to use systemic antibiotics with hot spots? which ones?
if there are satellite lesions or folliculitis

clavamox, cephalexin, clindamycin
what is intertrigo? what are some causes on a macroscopic level?
friction from skin surfaces rubbing together

breed standards, obesity, skin thickening from chronic inflammation
what are the microscopic causes of intertrigo?
glandular secretions get trapped
bugs break down sebum and make stinky stuff
what are examples of locations for intertrigo?
lip folds
facial folds
vulvar folds
tail folds
body folds
what's the treatment for intertrigo?
correct fold (else will be lifelong issue)
clip hair
remove surface debris
topical anti-inflammatory
impetigo: who gets it, how contagious is it, what conditions lead to it?
young animals
not contagious
dirty environment, poor nutrition
how can kittens get impetigo?
overzealous licking by mom
what do the lesions look like for impetigo? do they hurt/itch?
nonfollicular pustules

nonpainful, nonpruritic
how do you diagnose impetigo?
history/clinical signs

cytology of pustular exudate
how do you treat impetigo?
usually fixes itself

to speed up: topical abx clav, ceph etc creams or shampoos
recurrent superficial staph pyoderma aka superficial bacterial folliculitis

who gets it? what does it look like?
DOGS not really cats

looks like ringworm!
what's the bug involved in superficial staph pyoderma? where does it come from?
s. pseudintermedius. it's normal flora so infection usually DUE TO AN UNDERLYING DISORDER
what are some underlying causes of superficial staph pyoderma?
HS disorders
keratinization disorders
metabolic
immune def.
T/F primary infections of superficial staph pyoderma are rare
true.
what happens within a few weeks to a month of stopping abx with superficial staph pyoderma?
recurrent 2ndary infections
what do haired areas look/feel like with superficial bacterial folliculitis?
bumpy
small , raised fur tufts
"moth - eaten"
pustule with HAIR IN CENTER
what's a good way to find the underlying cause of superficial bacterial folliculitis?
locations of the lesion

axillary/inguinal= HS disorder
truncal/endocrine = metabolic
how do you diagnose superficial bacterial folliculitis?
cytology, skin scrape, fungal culture, biopsy, C+S if it's recurrent
how long should you treat superficial bacterial folliculitis? what should you avoid?
systemic abx for at least 21 days
treat 7 days past clinical cure

avoid steroids
with recurrent superficial bacterial folliculitis, how often should you bath them? what else can you do?
2-3 times a week

immune stimulant like staphage lysate or IFN-alpha.
what are nasal, juvenile, interdigital, and callus pyodermas examples of?
DEEP pyodermas
nasal folliculitis/furunculosis: onset, signs and causes
acute, painfule papules and crusts on the bridge of nose

probably local trauma or insect bite
who is predisposed to nasal pyodermas?
dolichocephalics
list some differentials for nasal pyoderma
insect (eosinophilic folliculitis)
immune (pemphigus/discoid lupus)
sunburn
trauma
neoplasm
what is juvenile cellulitis?
not really bacterial, unknown etiology, maybe HS rxn or possibly hereditary
who is predisposed to juvenile cellulitis?
young, short coated breeds

dachshunds and goldens
what does juvenile cellulitis look like?
acute facial swelling, inflammation, pain. papules, pustules, purulent exudate. abcesses may open and drain

giant submand and prescap LNs
how do you diagnose juvenile cellulitis?
rule out demodex
usually negative culture results early
history/clin signs
C+S
how do you treat juvenile cellulitis?
oral corticosteroids
abx do not work!
clean lesions
astringent soaks
systemic abx to prevent 2ndary infections
what's the most common pyoderma bacT in cats and dogs?
staph pseudintermedius, some proteus and pseudomonas

p. multocida in cats
what are the 2 normal flora in both cats and dogs?
dogs = s. pseudintermedius, s. schleiferi

cats = p. multocida, s. aureus
what are transient bacteria?
contaminants from environment, do not multiply and don't hang around long.
give examples of transient bacT in dogs and cats.
dogs - pseudomonas, proteus, myco

cats - myco
T/F intracellular cocci and degenerate neutrophils are NOT signs of a bacterial skin infection.
false.
T/F you want to treat bacterial pyoderma with systemic antibiotics
true.
penicillin is active mainly against gram + or -?
+
when do you want to STOP pyodermal treatment?
1-2 weeks AFTER clinical cure. VIP.
what are 3 narrow spectrum drugs to use for gram+ infections?
lincomycin
erythromycin
clindamycin
what 3 drugs do you want to use for recurrent skin infections?
clavamox
cephalexin
cefodoxime proxetil
what 2 drug classes do you use for mixed/deep infections?
fluoroquinolones
aminoglycosides
s. schleiferi is found on a dog/cat, what do you do?
culture and sensivity to avoid resistant strains!

4x the MIC dosage.
what 4 kinds of drugs are in shampoos?
benzoyl peroxide
chlorhexidine
ethyl lactate
monosaccharides
which shampoo drug is ototoxic?
chlorhexidine so don't use in ears if eardrum is ruptured.
name 3 functions of the skin
enclosing barrier

secretory/excretory

sensory
list the 3 layers of the skin
epidermis (corneum>lucidum>granulosum>spinosum>basale)

basal lamina

dermis (collagen, ground substance, glands)
what's the 1 most important diagnostic aid in dermatology?
history!
what are the stages of the hair cycle?
anagen = growth
catagen = transition
telogen = resting
what influences the hair cycle?
light
pregnancy n' parturition
disease states
endocrine (sex hormones + steroids)
thyroxine
which diagnostic test has the best cost:benefit ratio?
???????
what's an anagen:telogen ratio, and what does it tell you about an animal?
helps determine the cause of alopecia
how is the skin antimicrobial?
dry, physical barrier
fatty acids
inorganic salts
pH
IgG's and complement
resident microflora
list the functions of the hair coat.
???
define macule/patch
round FLAT change in skin coloration
define urticaria
hives

dark, red pruritic bumps
define papule
small solid elevation of the skin
define pustule
small elevation w' neutrophils
define epidermal collarette
peeling edge of epithelium surrounding an erosion or ulcer
define furunculosis
draining tract secondary to ruptured follicles
define abcess
accumulation of inflammatory cells and necrotic debris
define excoriation
superficial abrasion from self trauma
define erosion/ulcer
break in epidermis extending to dermis
define lichenification
thickening of the skin
define hyperkeratosis
thickened s. corneum
define comedo
dilated hair follicle
give 2 examples of alopecic disease
1) hairs epilate easily

2) "" don't
what exactly are dermatophytes?
keratinophilic fungal organisms that feed on the stratum corneum, nails and anagen hair
where do dermatophytes migrate to?
the keratogenous zone of the hair (adamson's fringe)
T/F dermatophytes make toxins and also suppress CMI
true.
how are dermatophytes transmitted? can it be in the environment?
by contact only!

yes, hair shafts laying around can be infectious for months.
what is the cat dermatophyte and the most common cause?
microsporum canis
what is the soil dermatophyte?
microsporum gypseum
what is the rodent dermatophyte?
trichophyton mentagrophytes
what are the 3 dispositions for dermatophytosis?
age
poor immune system
genetics
what are some factors that can suppress the immune system and predispose to dermatophytes?
FeLV, FIV, cancer, poor nutrition, drugs, metabolic disease
T/F EVERY dermatophyte species can be contagious
true.
T/F dermatophytes are in dogs more than cats.
false.

cats more than dogs.
describe the classic dermatophyte lesion.
annular area of peripherally expanding alopecia, scale, crust, papules, pustules on the face limbs, paws, and tail.
what are some other dermatophyte lesions aside from the "classic" lesion?
nasal folliculitis and furunculosis
generalized seborrhea
nail infection (onychomycosis)
____________ dermatophytosis is more common in cats.

what does this mean?
generalized.

alopecia, folliculitis, scale, crust
T/F dermatophytes also cause miliary dermatitis in cats.
false.

not really, usually from fleas.
what's the MOST reliable test to diagnose dermatophytosis and where's the best place to get it?
fungal culture

on the CHIN.
what is a Wood's lamp? how reliable is it?
fluoresces infected hairs yellow-green

not really great. only some strains glow and only about 50% of m. canis.
how would you microscopically examine hair for dermatophytes?
clear the keratin 10-20% KOH, hairs will be larger and fragmented with a loss of definition between parts.
where should you pluck the hairs from for a fungal culture?
the periphery of a lesion
what do you grow fungal cultures on? what's a + look like?
DTM (dermatophyte test medium)

media turns RED 10-14d for dermatophytes
T/F you shouldn't rely on color changes of the DTM do diagnose a dermatophyte infection.
true.

must ID it though morphologic/microscopic characteristics
Do dermatophytes spontaneously resolve?
if local in healthy dogs or shorthair cats.

not with a general infection

not with m. gypseum, persicolor
what are the goals for dermatophyte treatment?
correct underlying problem

reduce spread

hasted resolution of infection
what's the most effective topical tx for dermatophyte infection?
lime sulfur dip
how long should you continue dermatophyte treatment?
until 3 negative cultures.
T/F you should clip animals with dermatophyte infections
true.

controversial but recommended.
what's an alternative to the lime sulfur dip and what's the problem?
chlorhexidine + miconazole

$$$$$$$$$$
when do you want to do systemic tx for dermatophytes?
multifocal lesions
all long haired animals
CATS
if no response w/ 2-4 weeks topical tx
what's the main systemic dermatophyte tx? what's the drawback?
griseofulvin

bone marrow suppression
when should you NOT use griseofulvin for dermatophyte tx?
FeLV or other immune suppressing diseases
what are other drugs besides griseofulvin to treat dermatophytes?
ketoconazole or itraconazole
what's the big side effect of using ketoconazole?
its bad for the liver so hepatitis can happen.
how do you decontaminate the environment for treating dermatophytes?
destroy all animal possessions
vacuum all surfaces
steam clean carpet
bleach all non-sensitive surfaces
how do you treat a cattery for dermatophy infection?
stop breeding
have 3 rooms for separate classes
topical + systemic for all animals
topical for new/transitioning cats
tx till ALL cats are 3x neg culture
T/F vaccinating for dermatophytes are cool.
false

not protective.
what is sporotrichosis? what's the treatment?
"rose bush dermatitis"

itraconazole

ZOONOTIC.
what are the aquatic fungi?
oomycetes ie pythium
what dogs are predisposed to aquatic fungi?
german shepherds
what causes "swamp cancer"?
pythium! aquatic fungi
what meds do you treat pythium with?
itraconazole + terbenafine but they're probably not going to make it
WHERE is blasto mainly found and what are the lesions?
nitrogen rich soil (guano or bird poo)

nodular skin lesions, draining tracts, abscesses
what are 2 tx for blasto?
both conazoles
amphoteracin B
where does histo mainly act and what is the tx?
GI/respiratory more than skin

itraconazole, ampho B
where does coccidiodes hang out?
sandy alkaline soil, warm temps, low rain
who mainly gets coccidiodes? what are the lesions?
young, male dogs (cats rare)

coughing, dyspnea, fever, anorexia and skin lesions
how do you diagnose coccidiodes?
history of travel to southwest
biopsy
cytology unreliable
how do you treat coccidiodes?
conazoles and ampho B
who gets crypto commonly and from where?
cats, from pigeon poo.
what are some skin lesions for crypto and what other 2 systems can be involved?
nodules, ulcers

ocular and neuro.
when does malassezia dermatitis happen?
opportunistically, when resistance is decreased!
what are 4 predisposing factors to malassezia?
humidity
immune dysfunction
genetic
HS disorders
since malassezia is normal flora, how can you tell on cytology that its causing a problem?
if there's neutrophils or a ton of malassezia
T/F malassezia dermatitis is non-pruritic
FALSE. it's hella pruritic
T/F about half of malassezia patients have bacterial pyoderma too
true.
how do you diagnose malassezia?
impression swab, skin scrape

response to anti-yeast therapy
T/F griseofulvin ONLY works on dermatophytes
true.
what's the major treatment for malassezia?
FIX THE UNDERLYING CAUSE!
what's the topical/systemic treatment for malassezia? how long do you treat?
antifungal creams/lotions/shampoo/dips

conazoles systemically NOT griseofulvin

1-2 weeks past cure
look at these 4 important flea species
ctenocephalides felis/canis
echidnophaga gallinacea
pulex
which is the "face flea" or the "stick tight" flea?
echidnophaga gallinacea

poultry flea!
T/F flea eggs are sticky and they hatch in about 3 weeks after laying
false.

non-sticky and 1-10 days
T/F flea larvae are NONparasitic
true.
what do flea larvae eat and how long does this stage laft?
debris and dried blood

5-11 days
what does pupae emergence depend on?
temp and pressure
T/F the flea pupa is very resistant to drugs and drying out.
true.
what's the ideal temp for fleas?
65-80
T/F dogs can become tolerant to flea bites
true.
what are the 2 types of HS reactions associated with flea bites?
T I

T IV

IgE and basophils
where on dogs and cats do clinical signs of flea bite HS show?
caudal 1/3 of body
look at a these rule outs for flea bite hypersensitivity.
other HS: atopy, food allergy
bacterial folliculitis
sarcoptes
malassezia
dermatophyte
mycoses
drug rxn
cheyletiellosis
is an intradermal skin test really good for diagnosing flea bite sensitivity?
only if they got the type 1.
what are cholinesterase inhibitors used for? what are 2 types and which is bad for cats?
flea control
1) organophosphates (kill cats)
2) carbamates
what is the product in the majority of OTC dog flea meds?
permethrins!

synthetic pyrethins
kills cats