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25 Cards in this Set
- Front
- Back
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Calcium must be solubilized by ___ in stomach to Ca2+ |
HCl |
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Two main transport systems of Calcium |
Carrier mediated, and active |
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Apical membrane transporter of calcium |
TRPV6 |
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Transport of calcium is regulated by |
calcitriol |
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Cell polarity is maintained by 3 junctions: |
Tight, Adherens, Gap |
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Activators of calcium |
Vit D status, Diets low in calcium increase absorption (inc. PTH and Calcitrol), Aging |
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Inhibitors of calcium |
Caffeine, phytic acid and fiber, Oxalic acid, Zn and Mg, Unabsorbed FA |
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Main hormones regulating calcium |
PTH (acts in kidney and bones) Calcitriol acts in SI Calcitonin |
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Calcitonin and PTH work together to ___ |
maintain normal levels of calcium in blood |
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Reduces calcium when levels rise above normal and inhibits production of PTH |
Calcitonin |
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Calcium is stored in the ____, and ___ |
Mitochondria, Sacroplasmic Reticulum |
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External layer of bone, dense |
Coritcal |
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Internal bone metabolically active |
Trabecular |
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This layer of bone is easily depleted with Ca |
Trabecular |
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Osteoblast surrounded by bone that differentiate |
Osteocyte |
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Bone building cells |
Osteoblast |
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Break down bone |
Osteoclast |
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Bone remodeling is stimulated by intermittent levels of ___ |
PTH |
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Osteoclasts are ______ by PTH, calcitrol and ____ by calcitonin |
Upregulated, downregulated |
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Two forms of P |
Organic (bound to proteins, sugars, lipids. Requires digestion) Inorganic (binds to DNA RNA) |
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Phosphorus is digested as INORGANIC P by |
Passive Diff, Sodium Phosphate Co-Transporter (inc. by calcitriol) |
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Inhibitors of P |
Phytic acid, Mg, Al, Ca+ |
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In SI Phos transport is increased by |
Vit D |
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In the Kidney Phos absorption is increased by |
PTH |
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In the blood ___ decreases Phos/Ca levels by increasing the use by bone |
Calcitonin |
