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191 Cards in this Set

  • Front
  • Back
ecthyma contagiosum
parapox
dsDNA
orf
ecthyma contagiosum stages
1. papule
2. targe
3. Weeping nodule
4, Regenerative
5. Papullomatous
6. Regressive w dry crust
Milker's Nodule
Paravaccinia/parapox
crusting or central ulceration
Malignant pustule
anthrax
starts as small erythematous itchy papule
1-2 days ring of vesicles w central eschar, surrounding edema
few wks eschar sloughs --> shallow ulcer heals by granulation
painless but can have painful LAD
Afipia felis
small # of cat scratch disease
cat scratch uncommon systmeic
encephaopathy
osteolytic lesions
thrombocytopeni purpura
cat scratch other cutaneous
morbilliform
EN
erythema marginatum
LCCV
EM
oculoglandular syndrome of parinaud
cat scratch
painless
5% of pts
palpebral conjunctiva
bacillary angiomatosis CD4 count?
< 50
bacillary angiomatosis other organs?
bacillary peliosis hepatitis
bacillary peliosis splenis with thrombocytopenai
bacillary angiomatosis side effect of tx?
Jarisch-Herxheimer-like reaction
Brucelliosis skin? %? tx?
Malta Fever, Undulant Fever, Bang's disease
infected animals, raw goat milk, unpasterurized goat cheese
vets and farmers
flu-like illness
SKIN 20% violaceous papulonodules on trunk and LEs

TX: doxycycline or rifampin
Brucelliosis skin?
20%
violaceous papulonodular trunk and LE
EN
vasculitis
Burkholderia mallei
Glanders
gram neg rod
direct contact
nodule/pustule edema inoculation site
nasal ulceration and septum perforation
flu-like sx, f/c, diarrhea

Farcy buds: intramuscular and SQ nodules along lymphatic drainage

Farcy Pipes: firm cords along lymphtatics

Chronic:
malaise, painful SQ and IM abscesses
may drain or extend to joints

Tx: surgery then streptomycin and tetracycline
dog bite
cat bite
dog: pasteurella canis
cat: pasteruella multocida

Human bite: Eikenella corrodans
cotton mouth
water moccasin
coral snake
red next to yellow
crotalidae
rattllesnakes
copperheads
cottonmouth/moccasin
Elapidae
coral snakes
Snake venom
hydrolases
lactrodectus mactans
Southern black widdow
mc in N America
Lactodectus geometricus (brown) and Lactodectus hesperus (Western)
California Black Widdow
black widdow bite venom
alpha lactrotoxin
depolarizes neurons
increase intracellular calcium
uncontrolled exocytosis of neurotransmitters
black widdow antivenom
within 90 hours
loxosceles reculsa
brown reculuse
only 6 eyes compared to 8 other spiders
spingomyelinase D
loxosceles reculsa

phospholipase enzyme

interacts with serum amyloid protein

Hyaluronidase --> gravity dependent spread of eschars
bloxosceles reclusa bite painful
no
Tegenaria agrestis (Hobo)
tegenaria agrestis
hobo spider
necrotic arachnidism Pacific Northwest
Large, aggressive spiders
CHEVRON PATTERN on abdomen
funnel shaped webs
Painless bites w fast-onset induration, erythema, numbness
hobo spider
chevron on abdomen
Lycosidase
Wolf Spider
PAINFUL bites
Venom HISTAMINE
lymphangitis or eschar
Lycosidae
Wolf Spider
painful
HISTAMINE
Peucetia Viridans
Green spider
South US
bright green with red spots
black spines on legs
PAINFUL BITE WITH PRURITUS
Peucetia viridans
PAINFUL PRURITIC BITE
Phidippus fromosus
jumping spider
aggressive
mc biting spiders US
HYALURONIDASE
no systemic reactions
mc biting spider US
jumping spider
Phidippus formosus
PAINFUL
HYALURONIDASE
Phidippus formosus
Aggressive
mc biting spider US
HYALURONIDASE
PAINFUL BITE
Chiracanthium
Sac Spider
LIPASE
non-aggressive
nocturnal
PAINFUL BITES
mc scorpions US
centruroides scupturatus
Centruroides gertschi
most toxic scorpions US
centruroides sculpturatus
Centruroides exilicauda
scorpions venom
hemolytic and neurotoxic

Neuro: convulsions, coma, hyper/hypothermia
Caridopulm: arrhythmias, pulmonary edema, HTN

TX: local wound care, ice packs
antihistamines, antihypertensives, anticonvulsants
+/- antivenom questionable efficacy
centruroides sculpturatus
mc in US
mc toxic in us
centruroides gertschi
mc US
not mc toxic in US
centruroides exilicauda
hemiscorpius lepturus
scorpions
Iran and Iraq
high mortality
only scorpion in region to have related cutaneous

CYTOTOXIC all tissues

erythema, purpuric changes, bullae, necrosis, ulcers
Mortality: cardiopulm and renal failure
hemiscropius lepturus
iran and iraq
mortality cardiopulm and renal failure
Euproctis chyrsorrhoea
brown-tail caterpillar and moth
Megalopyge opercuiaris
Wolly or puss caterpillar
Megalopyge opercuiaris
Wolly or puss caterpillar
sibine stimulae
saddleback
automeris io
io caterpillar moth
phobetron pithecium
hag moth
Pyrrharctia Isabella
Wolly bear
Pyrrharctia isabella
wolly bear
Hemileuca maia
Buck moth caterpillar
Norape cretata
Flannel moth caterpillar
Hymenoptera
Vespidae: wasps, hornets, yellow jackets
Apis mellifera: honeybee
Bombus: bumblebee
Hymenoptera venom
HISTAMINE
MELLITIN
HYALURONIDASE
ACID PHOSPHATASE
PHOSPHOLIPASE A
solenopsis
invicta, geminata, richteri
SOLENOPSIN D
PIPERIDINE DERIVATIVE
HEMOLYTIC FACTOR

histamine, other vasoactive amines from mast cells
sandflys
5 mm
pass through nets
LUTZOMYIA
PHLEBOTOMUS
VERRUCARUM
Lutzomyia
sandfly
tropics in New world
new world leish
Phlebotomus
old world leish
sandfly
Lutzomyia Verrucarum
sandfly
peru, ecuador, columbia
BARTONELLA BACILLIFORMIS (Carrion's disease, Verruga Peruana, Oryoya fever)
Lutzomyia
phlebotomus sandfly
sandfly bites?
females
night biters
simulium bites?
females
daytime biters
blackfly fever
simulium

generalized edema
Chrysops
deer fly, mango fly
Loa Loa, tularemia
only female bites
PAINFUL BITES
Glossina
tsetse fly
African trypanosomiasis
hatchet cell wing
stomoxys
stable fly
protozoa
Culicoides
biting midges
1-4 mm
females NITE BITERS
glossinia
tsetse fly
African tyrpatanomyosis
Culicoides
biting midges
malaria
Anopheles
Yellow fever, dengue fever, chikungunya fever
Aedes
conenose bugs
reduvid bug
first sign of american trypatomosis?
delayed erythema PAINLES
ctenidia
combs fleas
siphonaptera
fleas
diamanus montanus
squirrel flea
plaque, tularemia
Coleoptera
beetles
Lytta vesicatoria
Spanish fly
Paederus eximus
Rove beelte
blister beetles
pederin
Paederus
Rove Beetle
blisering beetle
anthrenus scrophulariae
anthrenus verbasci
carpet beetles
ACD larvae
Anthrenus scrophulariae
Common carpet beetle and larvae
ACD to larvae
cordylobia anthropophaga
tumba fly
tropical africa
PLAQUE MYIASIS with many FURUNCULAR-LIKE LESIONS
deposits eggs on moist clothing and sand
trunk, thighs, buttocks
Hypoderma lineatum
common cattle grub
furuncular myiasis
Wohlfahrtia vigil
grey flesh fly
infant skin not adult skin
Cuterebra cuniculi
rabbit botfly
Cochliomyia hominivorax
(New World screwworm)
M/c cause of wound myiasis in Americas
nose and ears
brain
Chrysomyia bezziana
(Old World screwworm)
M/c Africa, Australia, Asia
May cause ocular infxn
Can cause bone erosions
Phaenicia sericata
(Green blowfly)
M/c fly identified in US urban study of wound myiasis
Assoc w/ homelessness, alcoholism & peripheral vascular dz
Hypoderma bovis
(Warble fly)
Exposure to infested cattle
Creeping Myiasis
Gasterophilus intestinalis
horse fly
creeping myiasis
Chilopoda/Diplopodia
Centipedes and Milipedes
chilopoda
centipedes
chevorn-shaped bite
NEUROTOXIC
PAIN, erythema, edema, bleeding, paresthesias
Scolopendra subspinipes
centipede Hawaii
diplopoda
millipedes
do not bite
secrete noxious chemicals

burn-like reactions, chemical dermatisis, brownish pigment
ocular inflammation
eat centipede
rhabdomyolysis and renal failure
anoplura
pediculosis
phthirus pubis
eggs up to 10 days
adult 36 hrs from host
oral ivermectin if rectal or eyelash involvement
acarina
ticks
amblyomma americanum
RMSF
Tularemia
human monocytic ehrlichiosis
Dermacentor
RMSF
Colorado Ticke Fever
Q Fever
Tularemia
Ehrilichiosis
Tick paralysis
rhipicpehalus sanguineus
brown dog tick
RMSF
boutonneuse fever
tularemia
mc vector RMSF
dermacentor variabilis
tick paralysis
dermacentor
ascending paralysis
human granulocytic ehrlichiosis
ixodes
argasidae
soft tick
borrelia duttoni
relaopsing fever
ornithodoros
ornithodoros
soft tick
tick paralysis
progressive lower motor neuron parlaysis
toxins presynaptic neuromuscular blockade
acarina
mites
allodermanyssus sanguineus
house mouse mite
rickettsia akari
demodex folliculorum
demodex brevis
demodex folliculorum above sebaceous gland
demodex brevis in sepaceous glands and vellous hair follicles
dermatophagoides farinae
house dust mites
acarus
cheese mite
tyrophagus
dired coconut
glycyphagus
grocery mite, hay and animla food
carpaglyphus lactis
dried fruit
rhizoglyphus hycainthi
onions, plant bulbs, tea
pyemotes tritici
grain itch or straw itch
pyemotes ventricosis
wood mites
trombiculid mites
leptotrombidium
rickettsia tsutsugamushi
srub typhus
ornithonyssus bursa
avian mite
hedgehog
trichophyton mentagophytes Norht Africa

salmonella

M mariium
M avium-intracelluare (European)

Urticaria from saliva
flying squirrel
toxo
staph
rickettsia prowazekii via body louse
Iguana
serratia marcescens
Herpes
Salmonella
chinchilla
trichophyton mentag
microsporum gypseum

Klebseilla pneumonae
Psuedomonas aeruginosa
Dasyatidae
Myliobatidae
most venomous fish
phylum chordata stingrays

hot water venom detoxified by heat
IV or IM meperidine hydrochloride
chordata
stingrays
sea urchins
hot water with vinegar to inactivate toxins
sea cucumber
conjunctivits
HOLOTHURIN
Linuche unguiculata
thimble jelly fish
southern waters
seabather's
Edwardsiella lineata
sea anemone larvae
Long Island NY
Seabather's
cercariae of avian shcistosomes
swimmer's itch
freshwater
chironex fleckeri
box jellyfish
most dangerous
shock
tape stripping skin
Physalia physalis
portuguese man of war
south waters of Atlantic
Physalia urticulus
blue bottle jellyfish
Cyanea and Chrysaora
sea nettles
jellyfish dermatitis
enterobius vermicularis tx
mebendazole
pyrantel pamoate
ancylostomiasis
hookworm
new world necator americanus
old world ancylostoma duodenale

ground itch feet and toes
papules and vesicles clear in 2 wks
skin to blood to lungs then swallow
iron deficiency anemia
ova in feces
ancylostoma baziliense
ancylostoma canium
dog and cat hookworm
gnasthostoma dolorosi
gnasthostoma spinigerum
raw fish or raw snake
migratory intermittent erythematous urticarial plaques
parasite 1 cm/hr
7-10 days, recur 2-6 wks
10 yrs
eosinophilic panniculitis

tx surgery w albendazole or ivermectin
strongyloides stercoralis
autoinfection perianal skin by larvae
10 cm/day
edematous red wheals fromlarval penetration
> 40 yrs
1/3 pts asymptomatic
urticaria, eosinophilic folliculitis

tx: ivermectin or thiabendazole
dracunculus medinensis
water flease cyclops
lower leg > genitalia, butt, arms
worm visable

tx surgery
flagyl to remove easier
wuchereria bancrofti
brugia malayi
brugia timori
adults lymphatics
microfilariae blood
mosquitos culex, aedes, anopheles, mnsonia

tx: DEC, ivermectin and surgery
tx filariasis
DEC
ivermectin, surgery
wuchereria bancrofti
brugia malayi
Wuchereria bancrofti
one nuclei in tail

burgia malayi
two nuclei in tail
mango fly bite
daytime
loa loa tx
DEC adults and microfilariae
21 days

do not treat if have onchocerciasis
Mazzotti reaction
acute hypersensitivity rxn to rapidly dying microfilariae after po DEC
onchocerchiasis tx
ivermectin kills microfilariae/prevents gravid females
multiple dose sto kill adult forms
only microfilariae with no nuclei in tip of tail
onchocerciasis
wuchereria bancrofti nuclei
one
trichinella spiralis
eat larvae cysts from pork, bear,walrus
cook kills
periorbital edema
splinter hemorrhages
dx IF ab test
Tx albendazole +/- steroids
echinococcus granulosus
dog tapeworm
echinococcus multilocularis
AGEP
tx excision or albendazole
cystercicosis
flat worm taenia solium
tx albendazole or praziquantel
surgery
diphyllobothrium latum
raw or undercooked fish
largest tapeworm
pernicious anemia

tx: niclosamide or praziquantel
sparganosis
spirometra dog/cat tapworm

application sparganosis contact with infected flesh tx infected eye with poultice

ingestion sparganosis snake or frog
cyclops infected w plerocercoid larveae
itchy or painful nodules trunk/legs

tx excision or ethanol
alconydium gelatinosum
dogger bank itch
visceral shistosomiasis associated with?
salmonella bacteremia
katayama fever
s japonicum
urticaria, fever, gi, arthritis, HSM, serum-sickness like reaction

dx eggs in stool

tx: praziquantel
mucocutaneous leish
L. braziliensis braziliensis
L. braziliensis panamensis
L. aethopica
espundia
leish
intradermal montenegro test
leish
kala-azar
visceral leish
patchy macular darkening of skin face and mid-abdomen
cutaneous nodule at site of sandfly
L donovanii
infantum
chagasi

RES
fever, wasting, epistaxis, HSM
anemia, thromobocytopenia

high mortality if no tx
black fever
kala-azar
viseral leish
dumdum fever
kala-azar
viseral leish
post kala-azar
variable
amastigoes
peidemics
leishman-donovan bodies
amastigoes Leish
mucocutaneous leish tx
pentavalent antimonial
meglumine antimonate
sodiumstibogluconate
fluconazole
ketoconazole
dapsone
pentamidine
reifampin
allopurnol
ampho B
Recidivans and disseminated leish
IFN terhapy
allopurinol and meglumine anitomonate
pentavalent antimonial side effects
cardio
hepatitis
n/v
thromobocytopenia
acute renal failure
amebiasis direct tissue lysis
galactose lectin

cathepsin B proteinase and collagenase

destroys no
amebiasis histo
trophozoites
toxo congenital
hydrocephalus
chorioretinitis
cerebral calcification
gamma-favre bodies
LGV
LGV diagnosis
complement fixation test
calymmatobacterium granulomatis
donovanosis
gangosa
late yaws
yaws cns and eyes
no
goundou
yaws
rare proliferative osteitis
nasal aspect of maxilla
yaws p/s
ppk
mc presentation endemic syphilis Bejel
mucous pathces
gangosa
endemic syphilis Bejel
Endemic syphilis Bejel eye?
neuro only eye uveitis, choroiditis, chorioretinitis, optic atrophy
pinta stage 1
small papule large 10 cm plaque 2-3 mths
no ulceration
legs and exposed skin
blood normal
darkfield positive
pinta stage 2
5 mths to 1 yr
psoriasis, tinea, syphilis, leprosy
exrtermities and face
red then gray, blue brown or hypopig
erythematous, desquamative, hypochromic or hyperchromic
non-treponemal test + 60%
darfield postive