Bugs And Drugs

Front 1

Rheumatic Fever

Scarlet Fever

Acute GN

Back 1

Streptococcus Pyogenes

Beta-Lactams or Erythromycin

Front 2

Tumbling motility, grows cold, mom ate soft cheese, baby got meningitis

Back 2

Listeria Monocytogenes

Ampicillin w/ Gentamycin added for IC's

Front 3

Lockjaw

Back 3

Clostridium tetani

Binds toganglioside receptors, blacks inhibitory mediators (GABA and Glycine) at spinal synapses.

Tx- Hyperimmune human globulin (TIG) to neutralize toxin, +metro or penicillin. AND Spasmolytic drugs (diazepam)

Front 4

Urease positive, gastric ulcers, type 1 carcinogen, predisposes to stomach cancer. Oxidase +, microaerophilic

Back 4

Helicobacter pylori


Omeprazole+amoxicillin+clarithromycin

Front 5

Most common cause of neonatal sepsis and meningitis

Back 5

Strep Agalactiae

Ampicillin with Cefotaxime or Gentamicin

Front 6

Obligate intracellular parasite affecting cooler parts of body, skin, mucous membranes, peripheral nerves

Back 6

Mycobacterium Leprae

Dapsone and Rifampin, with clofazimine added for lepromatous

Front 7

Acid fast rods with a waxy cell wall, auramine-rhodamine staining bacilli, GHON complexes

Back 7

Mycobacterium Tuberculosis

First 2 mo: INH+Rifampin+pyrazinamide+Ethambutol

Next 4 mo: INH+Rifampin

Front 8

Most common cause of bacterial pneumonia in adults

MCC Otitis media and Sinusitis in children

Back 8

Strep Pneumonia, Optichin sensitive

Penicillin G

Front 9

Large, boxcar-like spore forming rod.

papule with vesicles-->Black eschar. Pulm involvement in a woolsorter

Back 9

Bacillius anthracis

Ciprofloxacin or Doxy

Front 10

Gram+ filaments breaking up into rods, partially acid fast

Back 10

Nocardia

Sulfonamides

Front 11

Uses dextran to adhere to teeth

Back 11

Streptococcus Mutans (viridans family), Optichin resistant

Normal flora but can cause endocarditis on a damaged heart valve after dental work,

prophlax: Penicillin G w/ aminoglycoside

Front 12

Club shaped gram+ rod

Dirty gray pseudomembranes in oropharynx, can caue obstruction, bullneck, recurrent laryngeal nerve damage, heart damage

Back 12

Corynebacterium diphtheriae

Erythromycin and antitoxin

prevent with DTaP (toxoid aka inactivated toxin vaccine)

Front 13

Elderly smoker develops pneumonia, BYCE +

A/C ducts

Back 13

Legionella

Floroquinolone or Azythromycin w/ Rifampin for IC pts DRUG MUST PENETRATE CELLS, facultative anaerobe

Front 14

Woman with IUD, Sulfur granules

Back 14

Actinomyces, grows in areas of low O2 tension, obligate anerobe (ABC's)

SNAP!! (Sulfa-Nocardia, Actinomyces-Penicillin)
Ampicillin or Penicillin G and drainage

Front 15

PYR+, Hydrolyzes esculin in 40% bile and 6.5% NaCl.

During med procedures on GI/GU-->Bloodstream-->previously damaged heart valves-->endocarditis

Back 15

Enterococcus Faecalis

Vanco, cannot do anything if VRE

Front 16

Floppy Baby, ate honey

Back 16

Clostridium botulinum

coded for by a prophage (lysogenized by C. bot.), Blocks release of Ach at the myoneuronal jt.

Respiratory support, antitoxin

Front 17

Dorm room meningitis

Back 17

Neisseria Meningitidis

tx- Ceftriaxone,Penicillin G

vaccine- capsular polysaccharide capsule

prophylax with rifampin for close contacts

Front 18

Undulating Fever

Unpasteurized dairy products

Back 18

Brucella
Facultative intracellular
Unpasteurized dairy products

Rifampin and Doxy

Front 19

Treated with Clindimycin, now has diarrhea

Back 19

Clostridium Difficile

Tx- Metro

Front 20

Poultry

Guillain-Barre syndrome

Back 20

Campylobacter Jejuni

Motile, curved gram neg rods

Most common cause of infectious diarrhea in US

Erythromycin, Floroquinolones

Front 21

Whooping cough

+ Regan-Lowe and Bordet-Gengou media

Back 21

Bordetella Pertussis

Direct immunofluorescence on Nasopharyngeal smear.

Mucosal surface pathogen

ADP ribodylation of Gi, increases cAMP

DTaP, toxoid vaccine

Tx- Erythromycin

Front 22

Tick bite, handled/butchered rabbits

Back 22

Francisella Tularensis

Turalemia

Tx- Streptomycin

Front 23

Myonecrosis

Back 23

Aka Gas gangrene, due to contamination of open wound with soil or feces.

Clostridium Perfringens

Tx- Debridement, delayed closure, clindamycin and penicillin, and hyperbaric chamber

Front 24

Enterobacteriaceae family

Lactose fermenters

Back 24

KEE

Klebsiella
E.Coli
Enterobacter
(Citrobacter)

Front 25

Male urethritis, proctitis

Female endocervicitis

Infants- ophthalmia

Back 25

Neisseria Gonorrhea

UNcapsulated

tx- Ceftriaxone

Front 26

Enterobacteriaceae Family

Non Lactose Fermenters

Back 26

Sigella
Yersinia BOTH non motile, non H2S Producers

Proteus
Salmonella Motile, H2S producers

Front 27

Enterobactericae

Antigens

Back 27

O= Cell envelope
H= flagellar (motile cells only)
K= capsular polysaccharide antigen
Vi= Salmonela capsular antigen

Front 28

Hot tub folliculitis

Burn pts

DIABETICS

CGD infections

Back 28

Catalase + Fruity odor, bluish green color

Pseudomonas

Tx-T,C, Pipercillin, 3rd gen Cefalosporins

Front 29

Primary cause of UTI

Back 29

E.Coli

Tx ampicillin or sulfonamides for UTI

Front 30

+CYE

Plemorphic gram (-) rods, that require cysteine and iron

Back 30

Legionella

Decontaminate AC cooling tanks

Floroquinolone or azithromycin, or erythromycin. Add Rifampin if IC

Front 31

Day care

Back 31

Shigella
non-lactose fermenter

Fingers, Food, Flies, Feces

AB component toxin inhibits protein synthesis by clipping 60s.

Tx fluid and electrolyte replacement only in mild cases

Front 32

Alcoholic gets pneumonia

Back 32

Klebsiella pneumoniae

Red currant jelly sputum

aminoglycosides and cephalosporins

Front 33

Second most common cause of neonatal septicemia and meningitis

Back 33

E.Coli (#1 is GBS)

ampicillin plus cefotaxime

Front 34

Infection beginning in illeocecal region, liver and spleen affected, may see rose spots. Necrosis of peyer's patches.

Back 34

Typhoid fever, salmonella typhi

Produces H2S, gram neg rods, highly motile, Vi capsule

Ciprofloxacin or ceftriaxone

Front 35

Tremendous fluid loss

Rice water stools

Back 35

Vibrio Cholerae

OXIDASE +

Fluid and electrolyte replacement, doxy or cipofloxacin may shorten duration

Front 36

Watery diarrhea then turns bloody

positive WIDAL test

Chickens

Back 36

Nontyphoidal Salmonella (turtles too)

CAUSES OSTEOMYLITIS IN SICKLE CELL PTS

Abx not recommended

Front 37

Hamburger and petting zoos

Back 37

EHEC O157:H7

Causes HUS, NO FEVER (shigga)
Shigella-like veritoxin, nicks 60s subunit

Nothing recommended abx

Front 38

Undercooked or raw seafood poisining

Back 38

Vibrio parahaemolyticus

Front 39

LT

ST

Traveler's Diarrhea

Back 39

ETEC

LT- Heat labile toxin stimulates adenylate cyclase by ADP ribosylation of Gs --> increased cAMP-->outflow of Cl- and water

ST- Heat stable toxin causes diarrhea by stimulating guanylate cyclase

Electrolyte replacement

Front 40

Osteomylitis in a sickle cell or asplenic pt

Back 40

Salmonella (non typhoidal)

Front 41

Bubonic plague, Pneumonic plague

US desert southwest

Back 41

Yersinia Pestis

Mimics appendicitis (Enterocolitica, blood transfusions)
Pestis- Wild rodents bitten by infected flea, humans get by respiratory route--> MUST QUARANTINE

Tx Streptomycin with Tetracycline

Front 42

Oysters, fishermen

Back 42

Vibrio Vulnificus

Front 43

Swarming motility

Urase +

Back 43

Proteus mirabilis, vulgarus

UTI's, Septicemia, Kidney Stones

Urease raises PH of urine to cause kidney stones

Front 44

Proteus Tx

Back 44

Acute uncomplicated pyelonephritis in women can be treated with oral quinolones for 7-14 days, single-dose ceftriaxone or gentamicin followed by TMP/SMZ, or an oral cephalosporin or quinolone for 14 days as outpatient therapy. For hospitalized patients, therapy consists of parenteral (or oral once the oral route is available) ceftriaxone, quinolone, gentamicin (plus ampicillin), or aztreonam until defervescence. Then, an oral quinolone, cephalosporin, or TMP/SMZ for 14 days may be added to complete treatment

Front 45

Cat Bite

Back 45

Pasteurella

cellulitis with lymphadenitis

Tx Augmentin (Amoxicillin/Clavulanate)