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34 Cards in this Set

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Bacillus Anthracis
G+ Rod
Pulmonary Anthrax
DOC:
Ciprofloxaxin
Levofloxacin
Clindamycin
Doxycycline
Borrelia burgdorferi
Spirochete
Lyme Disease
DOC
Doxycycline
Amoxicillin
Ceftriaxone

ALTERNATIVES
Pen G, Cefotaxime, Azithromycin, clarithromycin
Bordetella pertussis
G- Rod
Whooping Cough
DOC
Macrolide (Azithro, Clarithro, Erythro)

Alternative
TMP/SMX
Brucella sp
G- Rod
Brucellois
doxy + either streptomycin or gentamicin
Alternative
(doxy, cipro + RIFampin)
Campylobacter Jejuni
G- Rod
Diarrhea
and Guillian barre
DOC:
Erythromycin, Ciprofloxacin
Chlamydia Trachomatis
Obligate Intracellular (G-)
Urethritis
DOC:
Doxycycline, Azithromycin,
Alternative
Erythromycin
Clostridium Difficile
G+ anaerobic
pseudomembranous Colitis
DOC
Metronidazole
Alternative
Vancomysin
Clostridium perfringens
G+ anaerobic
ellulitis or myonecrosis
DOC
penicillin + clindamycin

Alternative
(doxycycline)
Enterococcus sp
G+ Cocci
UTI, sepsis, endocarditis
DOC
penicillin, vancomycin, ampicillin + Amino Glycoside
Enterococcus sp
(vancomycin resistant)
G+ Cocci
UTI, sepsis, endocarditis
DOC
linezolid, quinupristin/dalfopristin
Francisella tularensis
G- Rod
tularemia
DOC
Streptomycin, gentamycin, tobramycin
Alternatives
Doxycycline, Ciprofloxacin
Gardnerella vaginalis
G variable Rod
vaginosis
DOC
metronidazole
Alternative
Clindamycin
Haemophilus influenzae
G- Rod
meningitis and other life threatening illness
DOC
Ceftriaxone, Cefotaxime
ALTERNATIVE
CIPROFLOXACIN
Helicobacter pylori
G-
peptic ulcer
DOC
PPI + clarithromycin +
amoxicillin or metronidazole
[many multi-drug regimens]
Klebsiella Pneumoniae
G- Rod Enteric
Pneumonia Red Currant Jelly
_______________________
UTI (UNCOMPLICATED)
DOC PNEUMONIA:
CEFTAZIDIME
ALTERNATIVE
Ciproflaxacin
UTI DOC:
FLouroquinolones
Listeria Monocytogenes
Gram + Rod (Motile) non spore forming
Meningitis
DOC
Ampicillin+Gentamicin
Alternative
TMP/SMX
Mycobacterium tuberculosis
•acid fast , obligate aerobe
Tuberculosis
DOC
rifampin + isoniazid + pyrazinamide + (ethambutol)
Mycoplasma pneumoniae
•Lack cell wall peptideglycan
•Cholesterol in membrane
Pnuemonia
DOC
Macrolides(azith,clarith,eryth)
Floroquinolones (cipro,moxi,Levo)
Alternative
Doxy
Neisseria gonorrhoeae
diplococcic Kidney bean shaped
• Catalase (+)
• Oxidase (+)
• IgA Protease
STD
DOC
Ceftriaxone
alternative
DOXYcycline
Neisseria meningitidis
diplococcic Kidney bean shaped
• Maltose Fermenter and Glucose Catalase (+)
• Oxidase (+)
• IgA Protease
Meningitis
DOC
Pen G
Alternative
Cefotaxime
Pseudomonas aeruginosa
G- Rod
sepsis (serious)
burn victims,
pneumonia- CF pt
osteomyelitis diabetics
DOC
AntiPsuedamonal Pencillin, 3rd gen ceph, imipenem, tobramycin, aztreonam, cipro
Rickettsia rickettsii
•Obligate intrcellular bacteria
dermacantor tick
•Rockymountin spoted fever
DOC
Doxycycline
alternative
Chloramphenicol
Salmonella sp
• Non lactose fermenting
•Motile and H2S producing
•OSTEOMYELITIS  Sickle Cell Pts
Enteric Fever
Typhoid fever
DOC
Ceftraixone, FLoroquinolones
Alternative
TMP/SMX
Shigella sp
• Non Lactose fermenting Non motile Non hydrogen sulfide producing
Can Propel itself inside the cell by stealing actin polymerization
dysentery
DOC
FloroQuinolones, azithromycin
Alternative
(TMP-SMX)
Streptococcus, Group
A or B
Pharyngitis
Pen G or V
(all beta-lactams or macrolides)
Streptococcus pneumoniae
(Penicillin sensitive)
pneumonia
pen G, amoxicillin, ceftriaxone, cefotaxime
Streptococcus pneumoniae
(Penicillin resistant)
pneumonia

levofloxacin, moxifloxacin, vancomycin, linezolid
Treponema pallidum
Spirochetes
syphilis
benzathine penicillin
Alternative
(doxy or tetracycline)

Yersinia enterocolitica
G- Rod
gastroenteritis
TMP-SMX, FQ
ALTERNATIVE
(3rd Ceph)
Yersinia pestis
PLAGUE
streptomycin or gentamicin
Alternative
(chloramphenicol, cipro, doxy)
Antibiotics TO AVOID In Pregnancy
Sulfanomides--> Kernicterus
Aminoglycosides-->Ototoxicity
FlQuinos--> Cartilage Damage
Erythromycin--> acute Cholestatic hematitis in mom ...
Clarithro--> Embyotoxic
Metronidazole--> Mutagenisis
Tetracyclines--> discolor teeth, inhibitiion of bone growth
Ribivarin (antiviral) Teratogenic
Grisofulvin(afungal) Teratogenic
Chloramphenicol--> Gray baby
Sporothrix Shecknii
The patient presents with ascending lymphangitis along the arm after yard work.The classic presentation is pustules and or ulcers at the site of injury with nodules along draining lymph nodes (ascending lymphangitis). Culture of the lesions shows cigar-shaped budding yeasts.

DOC : ITRACONAZOLE
Pregnant patient with UTI
DOC : Amoxicillin

Sulfa --> in fetus leads to kernicterus
Floro--> cartilage damage
tetras- --> avoided does damage to growing bones
This patient presents with the serologic markers of chronic hepatitis B. His liver enzyme levels also indicate a viral hepatitis. In viral hepatitis ALT>AST, and in alcoholic hepatitis AST > ALT. Patients with viral hepatitis B and C have an increased risk of developing hepatocellular carcinoma. Alpha-fetoprotein is a marker for hepatocellular carcinoma therefore (D) is the correct answer. Alpha-fetoprotein is also a tumor marker for yolk sac tumors. (A) is a tumor marker for hydatidiform moles, choriocarcinomas, and gestational trophoblastic tumors. (B) is a tumor marker for cancer that has metastasized to bone, obstructive biliary disease, and Paget’s disease of bone. (C) is a tumor marker for neuroblastoma. (E) is a tumor marker for colorectal, gastric, and pancreatic cancers.

Bottom Line: Hepatitis B and C predispose to hepatocellular carcinoma. α-fetoprotein is a tumor marker for hepatocellular carcinoma.
alpha fetoprotein