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5 Cards in this Set
- Front
- Back
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4 phases of the cardiac cycle
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1. Inflow
2. Isovolumetric contraction 3. Outflow 4. Isovolumetric Relaxation 2-3 systole |
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Mechanisms for relaxation of cardiac muscle
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Extrusion of Ca into ECF
Re-uptake of Ca by SR Dissociation of Ca from troponin-C |
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In cardiac muscle, Ca entry through _______ channels is necessary for activation of the release channels on the SR.
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L-type
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What occurs via adenyl cyclase through the activation of B1 and B2 receptors by Epi and NE?
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Converts ATP to cAMP, activates PKA, Opens Ca channels, contraction
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Other effect of PKA aside from increased contraction strength.
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Increased pumping of Ca into SR --> Increased speed of relaxation
Increased off-rate of Ca from Ca-Troponin-C complex. Increased speed of relaxation |
