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94 Cards in this Set

  • Front
  • Back

What is the fate of the paramesonephric duct in the female? In the male?

In the female, the Mullerian duct becomes:
oviduct
uterus
cervix
cranial vagina
(nothing in male)
What is the fate of the mesonephric duct in the female? In the male?
In the male, Wolffian duct becomes:
efferent ducts/ductules
epididymis
ductus deferens
(nothing in female)
What gene promotes male development? Where is it carried? What does it do?
SRY gene on Y chromosome promotes differentiation of Sertoli cells
What substance causes regression of the mullerian ducts? Where is it produced?
Mullerian inhibitory substance (produced by Sertoli cells)
Which is more common, male or female pseudohermaphrodites?
Male pseudohermaphrodite
What is the most common cause of male infertility?
Testicular degeneration (atrophy)
What are major causes of testicular degeneration?
Thermal regulation
Zn deficiencies
Hormone influences
Auto-immune dz
Toxins
Obstructions
Infections
What is a common cause of testicular hypoplasia?
Cryptorchidism
Which is more common, epididymitis or orchitis? What species is it common in?
Epididymitis more common;
Seen in rams and dogs
What are important causes of epididymitis in rams? In dogs?
Brucella, Actinobacillus, and Histophilus in rams
E. coli and Brucella in dogs
What are differentials for a dog with endocrine alopecia, pendulous prepuce, gyenecomastia, and enlarged testis?
Sertoli cell tumor (hyperestrogenism);
Cushings, hypothyroid
What is the most common testicular neoplasm in the horse? In the dog?
Horse - Seminoma
Dog - Leydig cell tumor
T or F:
Seminomas are the most common tumor of the horse and dog.
False! Most common in horse but 2nd most common in dog.
What are the four tumors of the testes?
Sertoli cell tumor
Leydig cell tumor
Teratoma
Seminoma
Leydig tumors are most common in which species? What do these tumors produce?
Dog and bull;
Produce androgens or estrogens
What is the most common cause of feminization?
Sertoli cell tumors!
Which tumor is common in foal cryptorchids?
Teratoma
What effect do androgens have on the prostate? Estrogens?
Androgens cause hyperplasia
Estrogens interfere w/proper differentiation
What are common bacterial causes of prostatitis?
E. coli
Proteus
Pseudomonas
Brucella
How can prostatic hyperplasia be differentiated from neoplasia?
Symmetry. Adenoma/Adenocarconoma will be asymmetric.
Incomplete closure of the urethra is...
...hypospadia
What are some major causes of balanopostitis?
Herpesvirus
Habronema spp.
What are common penile tumors and which species is prone to each?
SCC - horses
Fibropapilloma - bulls
Papilloma - pigs, horses
TVT - dogs
Sarcoid - horse sheath
What is a common neoplasm on the equine penis and prepuce?
SCC!!
What are the cell layers of the ovary and what does each produce?
Thecal cells - androstenedione
Granulosa cells - estrogen (from androstenedione) and Progesterone
What are the two endocrine cells of the testis? What does each produce? What stimulates each?
Leydig cells (stimulated by LH to produce T)
Sertoli cells (stimulated by FSH to produce androgen binding protein among other things)
What is strange about bitch ovaries (histologically)? What is important about this?
Have subsurface epithelial structures; these can become neoplastic?
If there is Leydig cell hypoplasia, what could be the cause?
Reduced LH (due to pituitary issue or GnRH issue)
What are the common ovarian neoplasms?
Sex cord stromal tumor
Epithelial tumors
Dysgerminoma
Teratoma
Which species commonly get sex cord stromal tumors? In which species are these tumors prone to metastasis?
Cats (common metastasis)
Dogs, cows
Mares (rare metastasis)
ID these testicular tumors
A - Seminoma
B - Sertoli cell tumor
C - Seminoma
D - Interstitial tumor (probably Leydig)
E - Seminoma
What is depicted in these ovaries? In which species is this common?
Cystic ovaries;
common in high-producing cows
Name that tumor!!~
Sex cord stromal tumor (ovary)
Name that tumor!
Sex cord stromal cell tumor (ovary, dog)
Ovarian epithelial tumors are common in which species?
Dogs
T or F:
Ovarian epithelial tumors are rarely metastatic.
False! They are often metastatic to the abdomen.
Why does ascites develop in concert with ovarian tumors?
lymphatic blockage
What is the ovaries' version of the seminoma?
Dysgerminoma
What is an important cause of vulvitis in horses? In cattle, goats and horses?
Taylorella equigenitalis;
Herpesviruses for cattle, horses, and goats (BHV-1, EHV-3, CapHV-1)
Why do fat old bitches get vulvitis?
Urine scalds
What are common masses found in the vagina, vulva, and cervix that are hormonally responsive?
Leiomyomas
Fibromatous polyps
What are vulvar masses common to mares?
To old gray mares?
SCC;
Melanoma
What are some causes of uterine atrophy?
Anestrus
Hypopituitarism & wasting (rare)
What condition is often a prelude to pyometra? What might cause this?
Endometrial hyperplasia secondary to hyperestrogenism or PG following estrogen priming
What condition is shown here?
Endometrial hyperplasia (thick uterine wall with bubble-like changes)
What generally causes a pseudopregnancy?
Prostaglandan influence
What are common uterine masses in the bitch? In the cow?
Bitch (leiomyomas/sarcomas)
Cow (Lymphosarcoma)
If you find lymphosarcoma in a cow, where else might you find it?
Heart
lymph nodes
abomasum
What are some differential diagnoses for equine metritis?
CEM (contagious equine metritis) caused by Taylorella equigenitalis;
(also S. zooepidemicus, E. coli, P. aeuriginosa, and Klebsiella pneumoniae)
What is the post-parturitent endometritis called?
Lochia
How big of a problem is a retained placenta in a horse? In a ruminant?
Horse is CRISIS
Ruminant is no big deal as long as it is <12hrs
What condition arises when a retained part of a placenta survives?
Subenvolution of placentocytes
Which species REQUIRE a CL to maintain pregnancy?
Cattle
Sheep
Goats
Pigs
Horses
How many fetuses must be present for a viable sow pregnancy?
4 (2 in each horn)
T or F:
Abortion is more common in farm animals than in cats/dogs.
True!
Cats/dogs have a "predetermined" CL lifespan; most EED is reabsorbed or mummified
What is the trigger inducing parturition?
Fetal stress! Once cortisol can be released from developed adrenals
When a dead fetus contaminated by putrefactive organisms it is called...
When is this common?
Maceration is common in dystocia and first trimester deaths
Describe the placental type of a:
Horse
Dog
Cow
Sheep
Pig
Cat
Dog/Cat - Zonary
Horse/Pig - Diffuse
Cow/Sheep - Cotyledonary
What is the significance of squamous metaplasia on the placenta?
No effect on fetus
What are some insignificant placental lesions that may be seen?
Uteroverdin
Amniotic plaques (squamous metaplasia)
Placental calcification
Hippomane (allantoic calculi)
What is going on here?
Uteroverdin
What is depicted here?
A - Amniotic plaques (squamous metaplasia)
B - Hippomane
C - Placental calcification
What are indications of placental insufficiency in ruminants?
Adventitial placentation
Placental wt <14% of fetal wt
What should be examined in an equine placenta?
should be ~10% of fetal wt
examine avillous sites (tips of horn, cervical star, endometrial cups)
umbilical cord should be 36-83cm
What causes the majority of EED?
Genetics
What specific components of dam illness contribute to abortion/stillbirth?
Oxygen (anemia)
Pyrexia (fetus expelled if temp too high)
Endotoxemia
T or F:
The success rate in successfully diagnosing abortion/stillbirth causes is pretty low.
True!
What are general steps in investigating abortion/stillbirth?
1) History
2) Dam exam
3) Serology (dam and other non-aborting dams)
4) Placental exam
5) Fetal exam
6) Estimate time of death
6) Fetal necropsy
What is the important part of the placenta to sample?
Chorioallantois
How dead is a fetus with dehydrated eyes?
Really dead....72 hours
How dead is a fetus with cloudy corneas and blood-tinged amniotic fluid?
mostly dead....12 hours
How dead is a fetus with gelatinous fluid in subcutis (anasarca)?
pretty dead...36 hours
What tissues are sampled for bacteriology in an abortion necropsy?
lung, liver, stomach content
What samples are taken fo virology in an abortion necropsy?
kidney, lung, thymus
What serological samples are taken in an abortion necropsy?
2mL fetal fluid
2mL maternal serum
What are common canine infectious agents involved in abortions?
Brucella canis, canine herpesvirus, neospora
What are common feline infectious agents involved in abortions?
FHV-1, calicivirus, FIV, FeLV
What are two important physical barriers preventing ascending infections in mammary glands?
Teat (streak) canal
Rosette of Furstenberg
Which hormone promotes mammary development? Which hormone helps with milk let-down?
PG promotes development
PRL helps with milk let-down
Name some mammary gland defense mechanisms against infection.
Normal flora
Rosette of Furstenberg/Teat canal
Flushing effect of milk
Lactoferrin, lysozyme, lactoperoxidase
Macrophages/neutrophils/antibodies
What are some causes of ischemic mammary necrosis?
Ergotism
Frostbite
T or F:
Ascending mammary infections are more common than hematogenous.
True
Which infectious mammary pathogen is an obligate inhabitant of the mammary gland?
Streptococcus agalactiae
Which infectious mammary pathogen causes watery, blood tinged milk?
Coliform mastitis (E. coli, Klebsiella pneumoniae, Enterobacter spp.)
Which infectious mammary pathogen is associated with improper maintenance of milking machines?
Coliform mastitis (E. coli, Klebsiella pneumoniae, Enterobacter spp.)
Which infectious mammary pathogen usually affects multiple quarters?
Mycoplasma bovis
Which infectious mammary pathogen is granulomatous and often iatrogenic?
Nocardia & yeasts
Which infectious mammary pathogen causes "blue bag" in sheep and goats?
Mannheimia haemolytica or Staphyloccus aureus
Which infectious mammary pathogen is common in sows?
Coliform mastitis (E. coli, Klebsiella pneumoniae, Enterobacter spp.)
Which infectious mammary pathogen can affect immature or dry glands?
Arcanobacterium pyogenes
Which tumor is associated with canine mammary neoplasia in males?
Sertoli tumors
Are mammary neoplasias normally benign in dogs? In cats?
Dogs - half and half
Cats - usually malignant
What is probably the most common canine mammary neoplasm?
Mixed mammary tumor
Where does neoplasia of the caudal two mammary glands metastasize to? The cranial 3?
Caudal - inguinal lnn
Cranial - axillary lnn