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61 Cards in this Set
- Front
- Back
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What are the 4 types of epulids? Which is the worst?
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Acanthomatous (invasive)
Fibromatous Ossifying Giant Cell |
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What is the most common oral tumor of cats? Dogs?
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Cats (SCC)
Dogs (malignant melanoma) |
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T or F:
Canned tuna is a suggested etiology for SCC development in the cat mouth. |
True! Also canned food, cigarette smoke, flea collars, and, of course, UV exposure!
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What are some curative agents for acanthomatous epulids that don't require radical surgery?
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Radiation (95% cure rate)
Intralesional bleomycin (100% cure rate) |
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Metastasis to which lymphoid tissues is common in feline oral SCC?
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Metastasis to lymph nodes is uncommon (he didn't say anything about the tonsils but I guess no to them as well)
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What is the best treatment for feline oral SCC? What is the MST?
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Hemimandibulectomy + radiation; MST of 14 months
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Metastasis to which lymphoid tissues is common in canine oral SCC?
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IF the SCC involves the tonsils of the tongue, 70% chance of mets to lymph nodes and other organs
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What is the common signalment for canine oral SCC?
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Older, large breed.
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When should cisplatin be used in cats?
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NEVER! Causes respiratory issues!
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Which is more invasive, feline or canine oral SCC?
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They pretty much are both really invasive!
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Which is more responsive to radiotherapy, feline or canine oral SCC?
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Canine oral SCC
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What is the best treatment for canine oral SCC?
a) mandibulectomy/maxillectomy b) chemotherapy + radiotherapy c) surgery + chemo d) surgery + radiotherapy |
d) surgery + radiotherapy
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What is the common signalment for canine oral malignant melanoma? What is the most common location?
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Older male dogs (gingiva)
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T or F:
Similar to oral SCC, oral malignant melanoma in dogs frequently involves the bone. |
True!
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Where are common metastatic sites for canine oral malignant melanoma?
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regional lymph nodes (70%)
tonsils (67%) lungs (15-70%) |
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T or F:
Over half of malignant melanomas are actually amelanotic. |
False! Its more like 30%.
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When should sentinel lymph nodes be aspirated in a case of malignant melanoma?
a) never b) when enlarged c) only with a malignant diagnosis d) always |
d) always; MM often affects regional lymph nodes and frequently (40% of the time) without any palpable lymphadenopathy.
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Which has a longer MST with radical surgery, canine SCC or malignant melanoma? Which has the higher recurrence rate?
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SCC is longer MST; MM is higher recurrence rate
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What are the 5 treatment options for malignant melanoma? Which has the best response rate?
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Surgery
Chemotherapy Radiotherapy (95% response) Immunotherapy Vaccine |
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What are the prognostic indicators for malignant melanoma?
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Size, location, and recurrence; also low mitotic figure on histopath
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What is the most common gastric cancer in dogs? What is the signalment?
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Gastric adenocarcinoma (older male Belgian Shepherds and Rough Coated Collies)
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Where is gastric adenocarcinoma typically found? What does it resemble?
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Found on the lesser curvature or pyloric antrum; resembles a leather bottle (linitus plastica)
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T or F:
Gastric adenocarcinoma has a very high metastatic rate. |
True!
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Which of the following treatments are effective for gastric adenocarcinoma?
a) surgery b) chemotherapy c) radiotherapy d) nsaid therapy |
a) surgery
d) nSAID therapy |
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What are prognostic indicators for gastric adenocarcinoma?
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Location
Ability for complete surgical resection Metastatic status |
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What is a common signalment for an anal sac adenocarcinoma?
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Older German Shepherd, Cocker Spaniel, Alaskan Malamute
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Why might a dog with an anal sac adenocarcinoma present with PU/PD?
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Hypercalcemia
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Where does anal sac adenocarcinoma metastasize?
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Spinal cord
bone lungs Lymph nodes (sub-lumbar) |
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What is the best therapy for an anal sac adenocarcinoma? What is the MST?
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Surgery + radiation + chemotherapy; 740-950d
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Poor prognostic indicators of anal sac adenocarcinoma include...
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...Metastasis
hypercalcemia large tumor size |
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T or F:
The second most common reason for hypercalcemia in the dog is cancer . |
False! It is #1 mack daddy!
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What is a common signalment for perianal adenoma? How are they treated?
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Intact males and spayed females; treated w/castration or cryotherapy (maybe estrogen)
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What is the most common tumor of the male repro system in the dawg?
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Testicular tumor
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What are the three different tissues from which testicular tumors can arise?
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Germinal epithelium
Sex cord stroma Mixed tumors |
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Which tumors are derived from the sex cords?
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Sertoli and leydig (male)
Granulosa, theoma, luteoma (female) |
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Which tumors are derived from the germinal epithelium?
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Seminoma, Embryonal carcinoma (male)
Dysgerminosa, teratocarcinoma (female) Teratoma (both) |
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Which testicular cell tumor commonly produces estrogen?
a) seminoma b) sertoli cell tumor c) teratoma d) leydig cell tumor |
b) sertoli cell tumor (45%)
(some seminomas can too) |
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Which benign testicular tumor secretes testosterone?
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Interstitial cell (leydig) tumor
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How are most testicular tumors treated?
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Castration
Carboplatin Maybe doxorubicin |
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Testicular tumors are often associated with:
a) testicles b) cryptorchid c) neuticles d) crap |
a) testicles
b) cryptorchid |
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Which breeds of bitches most commonly get reproductive tumors?
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Boxers, German Shepherds, Yorkies
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Which ovarian tumor is most common in bitches? Which has the lowest metastatic rate?
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Granulosa cell tumors (sex cord tumors) are the most common AND have the lowest metastatic rate.
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What are some clinical signs of E2 producing tumors?
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Vulvar enlargement
Serosanguinous vulvar discharge Persistent estrus Aplastic pancytopenia Alopecia |
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What are some clinical signs of progesterone producing tumors?
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Cystic endometrial hyperplasia
Pyometra |
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Which is better in terms of survival rate: ovarian cancer or testicular cancer?
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Testicular cancer
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What is the most common cancer of the dawg urinary system?
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TCC boyeeeeeeeeee
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Who gets TCC more often, bitches or pimps?
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bitches! 1:1.7 ratio
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What is a common signalment for TCC in dogs?
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Female scotty terrier w/bloody urine.
(also beagles, shetland sheep dog, wire haired fox) |
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Which gets more TCC, cats or dogs?
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Dogs! Almost NO TCC in cats
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Why is TCC associated with obesity?
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Obesity leads to toxin accumulation; toxins lead to TCC
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Where are most TCCs found?
a) urethra b) trigone c) apex d) prostatic involvement |
b) trigone
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Which of the following are good diagnostic tests for TCC?
a) ultrasound b) radiography c) FNA d) urine antigen test |
a) ultrasound
b) radiography d) urine antigen test |
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T or F:
Due to its high specificity, the urine antigen test can diagnose up to 90% of TCC. |
False! It does have a high SENSITIVITY but LOW SPECIFICITY; you get lots of false positives!
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What is the most appropriate treatment for TCC?
a) surgery + chemotherapy b) radiotherapy + NSAID c) surgery + NSAID d) surgery + chemotherapy e) chemotherapy + NSAID |
e) chemotherapy + NSAID
(Cisplatin or Mitoxantrone + peroxicam) |
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Who survives longer with TCC: spayed females or castrated males?
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Spayed females!
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Which drug is used to treat soft tissue sarcomas and lymphomas can cause perivascular sloughing?
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Vincristine or doxyrubicin
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Which drug should be avoided in a dog with VPCs?
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Doxyrubicin
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Which drug can cause sterile hemorrhagic cystitis?
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Cyclophosphamide
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Which two drugs should be AVOIDED IN CATS??
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5-FU
Cisplatin |
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Which drug should be avoided in mast cell tumors?
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Doxorubicin (causes mast cell degranulation)
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Anaphylaxis is associated with which drug(s)?
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L-Aspariginase
(also doxorubicin which causes mast cell degranulation) |
