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61 Cards in this Set

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  • Back
What are the 4 types of epulids? Which is the worst?
Acanthomatous (invasive)
Fibromatous
Ossifying
Giant Cell
What is the most common oral tumor of cats? Dogs?
Cats (SCC)
Dogs (malignant melanoma)
T or F:
Canned tuna is a suggested etiology for SCC development in the cat mouth.
True! Also canned food, cigarette smoke, flea collars, and, of course, UV exposure!
What are some curative agents for acanthomatous epulids that don't require radical surgery?
Radiation (95% cure rate)
Intralesional bleomycin (100% cure rate)
Metastasis to which lymphoid tissues is common in feline oral SCC?
Metastasis to lymph nodes is uncommon (he didn't say anything about the tonsils but I guess no to them as well)
What is the best treatment for feline oral SCC? What is the MST?
Hemimandibulectomy + radiation; MST of 14 months
Metastasis to which lymphoid tissues is common in canine oral SCC?
IF the SCC involves the tonsils of the tongue, 70% chance of mets to lymph nodes and other organs
What is the common signalment for canine oral SCC?
Older, large breed.
When should cisplatin be used in cats?
NEVER! Causes respiratory issues!
Which is more invasive, feline or canine oral SCC?
They pretty much are both really invasive!
Which is more responsive to radiotherapy, feline or canine oral SCC?
Canine oral SCC
What is the best treatment for canine oral SCC?
a) mandibulectomy/maxillectomy
b) chemotherapy + radiotherapy
c) surgery + chemo
d) surgery + radiotherapy
d) surgery + radiotherapy
What is the common signalment for canine oral malignant melanoma? What is the most common location?
Older male dogs (gingiva)
T or F:
Similar to oral SCC, oral malignant melanoma in dogs frequently involves the bone.
True!
Where are common metastatic sites for canine oral malignant melanoma?
regional lymph nodes (70%)
tonsils (67%)
lungs (15-70%)
T or F:
Over half of malignant melanomas are actually amelanotic.
False! Its more like 30%.
When should sentinel lymph nodes be aspirated in a case of malignant melanoma?
a) never
b) when enlarged
c) only with a malignant diagnosis
d) always
d) always; MM often affects regional lymph nodes and frequently (40% of the time) without any palpable lymphadenopathy.
Which has a longer MST with radical surgery, canine SCC or malignant melanoma? Which has the higher recurrence rate?
SCC is longer MST; MM is higher recurrence rate
What are the 5 treatment options for malignant melanoma? Which has the best response rate?
Surgery
Chemotherapy
Radiotherapy (95% response)
Immunotherapy
Vaccine
What are the prognostic indicators for malignant melanoma?
Size, location, and recurrence; also low mitotic figure on histopath
What is the most common gastric cancer in dogs? What is the signalment?
Gastric adenocarcinoma (older male Belgian Shepherds and Rough Coated Collies)
Where is gastric adenocarcinoma typically found? What does it resemble?
Found on the lesser curvature or pyloric antrum; resembles a leather bottle (linitus plastica)
T or F:
Gastric adenocarcinoma has a very high metastatic rate.
True!
Which of the following treatments are effective for gastric adenocarcinoma?
a) surgery
b) chemotherapy
c) radiotherapy
d) nsaid therapy
a) surgery
d) nSAID therapy
What are prognostic indicators for gastric adenocarcinoma?
Location
Ability for complete surgical resection
Metastatic status
What is a common signalment for an anal sac adenocarcinoma?
Older German Shepherd, Cocker Spaniel, Alaskan Malamute
Why might a dog with an anal sac adenocarcinoma present with PU/PD?
Hypercalcemia
Where does anal sac adenocarcinoma metastasize?
Spinal cord
bone
lungs
Lymph nodes (sub-lumbar)
What is the best therapy for an anal sac adenocarcinoma? What is the MST?
Surgery + radiation + chemotherapy; 740-950d
Poor prognostic indicators of anal sac adenocarcinoma include...
...Metastasis
hypercalcemia
large tumor size
T or F:
The second most common reason for hypercalcemia in the dog is cancer .
False! It is #1 mack daddy!
What is a common signalment for perianal adenoma? How are they treated?
Intact males and spayed females; treated w/castration or cryotherapy (maybe estrogen)
What is the most common tumor of the male repro system in the dawg?
Testicular tumor
What are the three different tissues from which testicular tumors can arise?
Germinal epithelium
Sex cord stroma
Mixed tumors
Which tumors are derived from the sex cords?
Sertoli and leydig (male)
Granulosa, theoma, luteoma (female)
Which tumors are derived from the germinal epithelium?
Seminoma, Embryonal carcinoma (male)
Dysgerminosa, teratocarcinoma (female)
Teratoma (both)
Which testicular cell tumor commonly produces estrogen?
a) seminoma
b) sertoli cell tumor
c) teratoma
d) leydig cell tumor
b) sertoli cell tumor (45%)
(some seminomas can too)
Which benign testicular tumor secretes testosterone?
Interstitial cell (leydig) tumor
How are most testicular tumors treated?
Castration
Carboplatin
Maybe doxorubicin
Testicular tumors are often associated with:
a) testicles
b) cryptorchid
c) neuticles
d) crap
a) testicles
b) cryptorchid
Which breeds of bitches most commonly get reproductive tumors?
Boxers, German Shepherds, Yorkies
Which ovarian tumor is most common in bitches? Which has the lowest metastatic rate?
Granulosa cell tumors (sex cord tumors) are the most common AND have the lowest metastatic rate.
What are some clinical signs of E2 producing tumors?
Vulvar enlargement
Serosanguinous vulvar discharge
Persistent estrus
Aplastic pancytopenia
Alopecia
What are some clinical signs of progesterone producing tumors?
Cystic endometrial hyperplasia
Pyometra
Which is better in terms of survival rate: ovarian cancer or testicular cancer?
Testicular cancer
What is the most common cancer of the dawg urinary system?
TCC boyeeeeeeeeee
Who gets TCC more often, bitches or pimps?
bitches! 1:1.7 ratio
What is a common signalment for TCC in dogs?
Female scotty terrier w/bloody urine.
(also beagles, shetland sheep dog, wire haired fox)
Which gets more TCC, cats or dogs?
Dogs! Almost NO TCC in cats
Why is TCC associated with obesity?
Obesity leads to toxin accumulation; toxins lead to TCC
Where are most TCCs found?
a) urethra
b) trigone
c) apex
d) prostatic involvement
b) trigone
Which of the following are good diagnostic tests for TCC?
a) ultrasound
b) radiography
c) FNA
d) urine antigen test
a) ultrasound
b) radiography
d) urine antigen test
T or F:
Due to its high specificity, the urine antigen test can diagnose up to 90% of TCC.
False! It does have a high SENSITIVITY but LOW SPECIFICITY; you get lots of false positives!
What is the most appropriate treatment for TCC?
a) surgery + chemotherapy
b) radiotherapy + NSAID
c) surgery + NSAID
d) surgery + chemotherapy
e) chemotherapy + NSAID
e) chemotherapy + NSAID
(Cisplatin or Mitoxantrone + peroxicam)
Who survives longer with TCC: spayed females or castrated males?
Spayed females!
Which drug is used to treat soft tissue sarcomas and lymphomas can cause perivascular sloughing?
Vincristine or doxyrubicin
Which drug should be avoided in a dog with VPCs?
Doxyrubicin
Which drug can cause sterile hemorrhagic cystitis?
Cyclophosphamide
Which two drugs should be AVOIDED IN CATS??
5-FU
Cisplatin
Which drug should be avoided in mast cell tumors?
Doxorubicin (causes mast cell degranulation)
Anaphylaxis is associated with which drug(s)?
L-Aspariginase
(also doxorubicin which causes mast cell degranulation)