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23 Cards in this Set
- Front
- Back
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T or F:
In general, the sympathetic and parasympathetic nervous systems are antagonistic. |
True
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What type of parasympathetic receptor is located on cardiac muscle? Sympathetic receptor?
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Para - Muscarinic
Sym - Alpha and Beta |
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T or F:
All preganglionic fibers release ACh into a synapse which stimulates Nicotinic receptors. |
'tis true!
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What neurotransmitter is used at Muscarinic receptors?
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ACh
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What type of receptor is at somatic muscle synapse? What is the neurotransmitter?
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Nicotinic; ACh
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What type of sympathetic receptor is found on renal vascular smooth muscle?
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Dopaminergic
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What ocular effect would be seen with parasympathetic stimulation? Parasympathetic blockade?
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Miosis (constriction) with stimulation
Mydriasis (dilation) with blockade |
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What ocular effect would be seen with a sympathetic stimulation? Sympathetic blockade?
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Mydriasis (dilation) with stimulation
Miosis (constriction) with blockade |
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How can you test for Horner's Syndrome? What would you expect in a positive test? Negative test?
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Apply pilocarpine (parasympathetic agonist);
Positive = RAPID pupil constriction Negative = SLOW pupil constriction |
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What is the function of alpha-1 receptors?
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Constrict blood vessels
Relax GI tract |
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What is the function of alpha-2 receptors?
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aggregates platelets
Decreases norepinephrine release from nerve terminals |
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What is the function of beta-1 receptors?
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increases rate and force of contraction of the heart
relaxes GI tract |
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What is the function of beta-2 receptors
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increases norepinephrine release from nerve terminals
dilates bronchi |
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What is the function of beta-3 receptors?
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thermogenesis
lipolysis |
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Choose alpha-1 or 2; beta-1, 2, or 3....
...relaxes GI tract |
Alpha-1
Beta-1 |
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Choose alpha-1 or 2; beta-1, 2, or 3....
...affects norepinephrine release from nerve terminals |
Alpha-2 (decreases release)
Beta 2 (increases release) |
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Choose alpha-1 or 2; beta-1, 2, or 3....
...constricts blood vessels |
Alpha-1
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Choose alpha-1 or 2; beta-1, 2, or 3....
...acts on heart muscle. |
Beta-1
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Choose alpha-1 or 2; beta-1, 2, or 3....
... |
Alpha-1
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What are non-selective adrenergic agonists?
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Norepinephrine
Isoproternol Dopamine Dobutamine |
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Rifampin induces p450s in the liver and intestine in your patient. This change in the liver will result in which of the following?
A. Reduces systemic drug concentrations B. Increases tolerance C. Increases AUC D. Has no effect on PK/PD E. Increases F |
A. Reduces systemic drug concentrations
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Neostigmine is used as a treatment for myasthenia gravis. Which of the following BEST describes the type of receptor interaction based on the mechanism of action of this drug?
A. Full agonist B. Partial agonist C. Partial antagonist D. Inverse agonist E. Indirect agonist |
E. Indirect agonist
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Each of the following choices will reduce the production of stomach acid in your patient. Which of the following, however, is likely to produce the greatest reduction in gastric acid?
A. Omeprazole B. Ranitidine C. Cimetidine D. Nizatidine E. Famotidine |
A. Omeprazole
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