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52 Cards in this Set
- Front
- Back
What is the CNS? What does it contain?
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Central Nervous System
Brain and Spinal Cord Gray/White matter and nuclei |
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What is the difference between a nucleus and a ganglion?
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A nucleus is a collection of nerve cell bodies within the CNS and a ganglion is a collection of nerve cell bodies in the PNS.
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What is the CNS tissue that contains no nerve cell bodies?
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White matter
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How can one tell gray matter from white matter histologically?
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White matter has empty spaces where axons once were.
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What are the two main classes of neurons?
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Neurosecretory (endocrine)
Transmission |
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Name the parts of a transmission neuron
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Dendrites
Cell body (Perikaryon) Axon Synaptic terminal |
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What does a pacinian corpuscle sense?
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Mechanical pressures
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What do encapsulated nerve endings detect? Free nerve endings?
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Pressure and temperature.
Respond to chems released by injured tissue. |
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What is found in the trophic zone?
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Perikaryon or neuronal cell body
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What differentiates the axon hillock from the beginnings of other dendrites?
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The axon hillock has no Nissl substance
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What does the axon contain?
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Neurofilaments
Neurotubules Mitochondria Voltage-gated Na channels |
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What differentiates a synaptic terminal from a dendrite?
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Synaptic terminals have secretory vesicles.
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What kind of neuron has one dendrite and one axon? Where might they be found?
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Bipolar neuron
Nose & ears (olfaction and audition) |
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What distinguishes a unipolar neuron? Where might they be found?
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Cell body is not in direct signal pathway. Found in dorsal root ganglion (sensory ganglion)
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What kind of neuron has one axon but multiple dendrites? Name two special shapes of this neuron type.
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Multipolar neuron.
Piriform neuron (Perkinje cell) Pyramidal neuron |
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What is the most common kind of synapse?
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Axo-dendritic
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What are the three parts to a synapse?
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Presynaptic element (synaptic terminal)
Synaptic cleft Postsynaptic element |
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What kind of channels are in the axonal and pre-snyaptic region? What kind in the synaptic cleft?
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Voltage-gated Na channels
Voltage-gated Ca channels |
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What holds a synapse together? What advantage does this afford?
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Neurofilament
Closer membranes = faster diffusion of transmitters |
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What percentage of all nervous cells are neurons? What cells make up the difference?
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10%; Glial cells
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What glial cells are found in the CNS?
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Astrocytes
Oligodendrocytes Microglia Ependymal Cells |
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What glial cells are found in the PNS?
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Neurolemmocytes (Schwann Cells)
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What astrocytes are found in gray matter? In white matter?
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Protoplasmic astrocytes
Fibrous astrocytes |
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How can astrocytes be identified?
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Largest nucleus in gray matter that is not a neuron;
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What are functions of astrocytes?
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Neural support cells
Neuron secret service (take up excess K, glutamate, water...) Form boundaries w/blood vessels Diffusion barriers at synapses |
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What astrocytic processes form blood vessel boundaries?
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Pedicels (Astrocytic end feet)
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What is the most common glial cell in the CNS?
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Oligodendrocyte
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What is the function of oligodendrocytes?
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Form myelin sheath around CNS axons.
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What do oligodendrocytes look like?
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Small, oval to spherical heterochromatic nucleus
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How are oligodendrocytes found in white matter?
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Find white space where axon was; nucleus is oligodendrocyte
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How many axons can an oligodendrocyte myelinate?
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Multiple axons
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What is the space between myelinated sections called? What is found in this space?
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Internode or Node of Ranvier
Na channels |
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What is the function of microglia? What is their cellular lineage?
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Antigen processing and phagocytosis.
Macrophage lineage. |
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How can a microglia be identified?
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Find cell nucleus in endothelium of capillary; microglial nucleus is same size.
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Where are ependymal cells found?
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Ventricles of brain and central spinal canal
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What cells produce CSF? Where are they found?
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Modified ependymal cells in the choroid plexus
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What is the electrolyte makeup of CSF?
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Low Ca and K
High Na, Cl, and Mg |
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What is the function of neurolemmocytes?
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Protect and/or myelinate neurons of the PNS
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How many cells can a neurolemmocyte myelinate? How many can it progect?
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Myelinate one axon.
Protect many axons. |
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How does a neurolemmocyte stain?
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Acidophilically (neurokeratin)
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What is the name for the cell that protects PNS cell bodies? These are a subclass of what what type of glial cell?
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Satellite Cells
Neurolemmocytes (Schwann) |
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What is the capillary-filled CT covering around an axon and neurolemmocyte? What type of CT is it?
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Endoneurium capillaries; loose CT
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What CT covers a nerve fasicle? What CT covers an entire nerve? What type of CT are these?
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Perineurium
Epineurium Dense Irregular CT |
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What differentiates an autonomic ganglion neural cell body from a sensory ganglion neural cell body?
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Sensory ganglion neural cell bodies have a central nucleus and peripheral neural cell bodies have an eccentric nucleus
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What makes up the neuropil? Where is neuropil found?
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1) Neuron cell bodies and dendrites, unmyelinated axons, oligodendrocytes, protoplasmic astrocytes, microglia
2) Gray matter |
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What is gray matter on the surface of cerebrum and cerebellum called?
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Cortex
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What structures contain grey matter and where are they located?
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Cortex - surface of cerebrum and cerebellum
Nuclei - brainstem, cerebellum, and cerebrum Cell Columns - spinal cord |
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Where are piriform neurons found?
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In the grey matter of the cerebellum
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What are the smallest type of neuron in the brain?
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Granule cells
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Quien estan "Los Reyes de Meninges?"
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Only the hottest mariachi band this side of the border!
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What are meningeal layers and spaces?
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Dura mater
Subdural space Arachnoid membrane Sub arachnoid space Pia mater |
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T or F
Dura mater is dense, irr CT and Pia mater is loose CT |
True! Hard mutha be dense yo and tender momma shows her areolae!
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