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52 Cards in this Set

  • Front
  • Back
What is the CNS? What does it contain?
Central Nervous System
Brain and Spinal Cord
Gray/White matter and nuclei
What is the difference between a nucleus and a ganglion?
A nucleus is a collection of nerve cell bodies within the CNS and a ganglion is a collection of nerve cell bodies in the PNS.
What is the CNS tissue that contains no nerve cell bodies?
White matter
How can one tell gray matter from white matter histologically?
White matter has empty spaces where axons once were.
What are the two main classes of neurons?
Neurosecretory (endocrine)
Transmission
Name the parts of a transmission neuron
Dendrites
Cell body (Perikaryon)
Axon
Synaptic terminal
What does a pacinian corpuscle sense?
Mechanical pressures
What do encapsulated nerve endings detect? Free nerve endings?
Pressure and temperature.
Respond to chems released by injured tissue.
What is found in the trophic zone?
Perikaryon or neuronal cell body
What differentiates the axon hillock from the beginnings of other dendrites?
The axon hillock has no Nissl substance
What does the axon contain?
Neurofilaments
Neurotubules
Mitochondria
Voltage-gated Na channels
What differentiates a synaptic terminal from a dendrite?
Synaptic terminals have secretory vesicles.
What kind of neuron has one dendrite and one axon? Where might they be found?
Bipolar neuron
Nose & ears (olfaction and audition)
What distinguishes a unipolar neuron? Where might they be found?
Cell body is not in direct signal pathway. Found in dorsal root ganglion (sensory ganglion)
What kind of neuron has one axon but multiple dendrites? Name two special shapes of this neuron type.
Multipolar neuron.
Piriform neuron (Perkinje cell)
Pyramidal neuron
What is the most common kind of synapse?
Axo-dendritic
What are the three parts to a synapse?
Presynaptic element (synaptic terminal)
Synaptic cleft
Postsynaptic element
What kind of channels are in the axonal and pre-snyaptic region? What kind in the synaptic cleft?
Voltage-gated Na channels
Voltage-gated Ca channels
What holds a synapse together? What advantage does this afford?
Neurofilament
Closer membranes = faster diffusion of transmitters
What percentage of all nervous cells are neurons? What cells make up the difference?
10%; Glial cells
What glial cells are found in the CNS?
Astrocytes
Oligodendrocytes
Microglia
Ependymal Cells
What glial cells are found in the PNS?
Neurolemmocytes (Schwann Cells)
What astrocytes are found in gray matter? In white matter?
Protoplasmic astrocytes
Fibrous astrocytes
How can astrocytes be identified?
Largest nucleus in gray matter that is not a neuron;
What are functions of astrocytes?
Neural support cells
Neuron secret service (take up excess K, glutamate, water...)
Form boundaries w/blood vessels
Diffusion barriers at synapses
What astrocytic processes form blood vessel boundaries?
Pedicels (Astrocytic end feet)
What is the most common glial cell in the CNS?
Oligodendrocyte
What is the function of oligodendrocytes?
Form myelin sheath around CNS axons.
What do oligodendrocytes look like?
Small, oval to spherical heterochromatic nucleus
How are oligodendrocytes found in white matter?
Find white space where axon was; nucleus is oligodendrocyte
How many axons can an oligodendrocyte myelinate?
Multiple axons
What is the space between myelinated sections called? What is found in this space?
Internode or Node of Ranvier

Na channels
What is the function of microglia? What is their cellular lineage?
Antigen processing and phagocytosis.
Macrophage lineage.
How can a microglia be identified?
Find cell nucleus in endothelium of capillary; microglial nucleus is same size.
Where are ependymal cells found?
Ventricles of brain and central spinal canal
What cells produce CSF? Where are they found?
Modified ependymal cells in the choroid plexus
What is the electrolyte makeup of CSF?
Low Ca and K
High Na, Cl, and Mg
What is the function of neurolemmocytes?
Protect and/or myelinate neurons of the PNS
How many cells can a neurolemmocyte myelinate? How many can it progect?
Myelinate one axon.
Protect many axons.
How does a neurolemmocyte stain?
Acidophilically (neurokeratin)
What is the name for the cell that protects PNS cell bodies? These are a subclass of what what type of glial cell?
Satellite Cells
Neurolemmocytes (Schwann)
What is the capillary-filled CT covering around an axon and neurolemmocyte? What type of CT is it?
Endoneurium capillaries; loose CT
What CT covers a nerve fasicle? What CT covers an entire nerve? What type of CT are these?
Perineurium
Epineurium
Dense Irregular CT
What differentiates an autonomic ganglion neural cell body from a sensory ganglion neural cell body?
Sensory ganglion neural cell bodies have a central nucleus and peripheral neural cell bodies have an eccentric nucleus
What makes up the neuropil? Where is neuropil found?
1) Neuron cell bodies and dendrites, unmyelinated axons, oligodendrocytes, protoplasmic astrocytes, microglia
2) Gray matter
What is gray matter on the surface of cerebrum and cerebellum called?
Cortex
What structures contain grey matter and where are they located?
Cortex - surface of cerebrum and cerebellum
Nuclei - brainstem, cerebellum, and cerebrum
Cell Columns - spinal cord
Where are piriform neurons found?
In the grey matter of the cerebellum
What are the smallest type of neuron in the brain?
Granule cells
Quien estan "Los Reyes de Meninges?"
Only the hottest mariachi band this side of the border!
What are meningeal layers and spaces?
Dura mater
Subdural space
Arachnoid membrane
Sub arachnoid space
Pia mater
T or F
Dura mater is dense, irr CT and Pia mater is loose CT
True! Hard mutha be dense yo and tender momma shows her areolae!