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14 Cards in this Set
- Front
- Back
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TH1 are known to secrete
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IL-2 and IFN-gamma
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Acute cellular rejection is characterized by
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Lymphocytes, CD4+ and CD8+
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Recurrent bacterial infections with; pneumococci, staphylococci, H.influenza. Neutrophils still function to fight off viral, fungal, and killing of bacteria
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X-linked agammaglobinemia or Bruton
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Failure of antibody synthesis of pre-B cell to B-cell b/c of a mutation in BTK
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BTK, B cell Tyrosine Kinase
X-linked agammaglobinemia |
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Digeorge's syndrome has aberrant embryonic formations of
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3rd and 4th brachial arches; hypoplasia of thymus, parathyroid, middle ear, mandible, aortic arch
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REcurrent viral and bacterial infections and tetany with hypocalcemia
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Digeorge's Syndrome; thymic hypoplasia
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CATCH22
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C ardiac defects
A bnormal facies T hymic hypoplasia C left pallet H ypocalcemia 22 chromosome Digeorge's symptoms |
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Immunodeficiency with thromobocytopenia and eczema
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Wiskott-Aldrich Syndrome
Poor antibody response to polsaccharide antigens X-linked Total immunoglobins are normal |
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CREST syndrome
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C alcinosis
R aynauds phenomenon E sophageal dysfunction S clerodactyly T elangiectasia |
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Widespread fibrosis and degenrative changes of skin, GI, heart, esophagus, muscle,
ANTI-SCL 70 + ANA |
Progressive systemic sclerosis,PSS
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What type of rejection? Generalized maculopapular rash, early jaundice, profuse diarrhea
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GVH:Attack of host epithelial by donor CD8+ cells
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Scleroderma is best characterized with this antibody test?
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Anticentromere antibodies
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Occurs mainly in women peak incidence is 30-40; Athralgias, Raynaud's phenomenon, esophageal hypomotility, and myositis. SPECIFIC ANA'S; ANTI-nRNP
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MCTD; mixed connective tissue disorder
CAN BE CONFUSED WITH SCLERODERMA |
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Marked deficiency in B and T cells; profound lymphopenia
Severe infections: bacterial, viral, and fungal Failure to thrive |
SCID; severe combined imunnodeficiency disease
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