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18 Cards in this Set
- Front
- Back
Parasympatholytic drugs used for bronchodilation
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1) Atropine sulfate or atropine
2) ipratropium bromide (Atrovent) 3) ipratroprium bromide & albuterol *a sympathomimetic (Combivent) |
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List the 3 drug classes for Sympathomimetic bronchodilation.
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1) Catecholamines
2) Resorcinols 3) Saligenins |
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Drugs included in the catecholamine class
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1) epinephrine (Adrenalin, Primatene Mist)
2) racemic epinephrine (Vaponefrin, Micronefrin, and AsthmaNefrin) 3) isoproternol (Isuprel, Isuprel Mistometer) 4) isoetharine (Bronkosol, Bronkometer) 5) bitolterol (Tornalate) *also a Pro-drug 6) formoterol |
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Drugs included in the resorcinol class
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1) metaproternol (Alupent, Metaprel)
2) terbutaline (Brethine, Bricanyl, Brethine, and Bambuterol *also a pro-drug) |
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Drugs included in the saligenin class
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1) albuterol (proventil, ventolin)
2) pirbuterol (Maxair) 3) salmeterol (Serevent) 4) levalbuterol (xopenex) |
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pirbuterol
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Trade name: Maxair (MDI)
Class: saligenin ROO: 5-8 mins. DOA: 5 hrs. Avail as an MDI, PO 10-15 mg or syrup 7.5mg/5ml Receptor: (ß2>ß1) |
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salmeterol
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Trade name: Serevent (DPI or MDI)
Class: Saligenin ROO: 20 min. DOA: 12 hours Receptor: (ß2) |
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epinephrine
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Trade names: Adrenalin (Neb), Primatene Mist (MDI)
Class: Catecholamine ROO: 3-5 min DOA: 1-3 hrs. Receptor: (a,ß) |
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Racemic Epinephrine
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Trade name: Vaponefrin (Neb), Micronefrin (Neb), AsthmaNefrin (Neb)
Class: Catecholamine ROO: 3-5 min DOA: 30 min-2 hr Receptor: (a,ß) |
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isoproternol
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Trade name: Isuprel (Neb), Isuprel-Mistometer (MDI)
Class: Catecholamine ROO: 2-5 min DOA: 30min-2 hr Receptor: (ß1,ß2) |
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isoetharine
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Trade name: Bronkosol (Neb), Bronkometer (?)
Class: Catecholamine ROO: 1-6 min DOA: 1-3 hr Receptor: ß2>ß1 |
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bitolterol
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Trade name: Tornalate (MDI)
Class: Catecholamine Pro-drug ROO: 3-4 min DOA: 5-8 hr Receptor: ß2>ß1 |
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metaproternol
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Trade name: Alupent (Neb), Metaprel (MDI)
Class: Resorcinol ROO: 1-5 min DOA: 6 hr Receptor: ß2>ß1 |
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terbutaline
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Trade name: Brethine, Brethaire (MDI), Bricanyl, and Bambuterol (bambuterol is a pro-drug)
Class: Resorcinols ROO: 5-30 min DOA: 3-6 hr Receptor: ß2>ß1 |
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albuterol
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Trade name: Proventil (MDI, DPI, Neb), Ventolin (MDI, DPI, Neb)
Class: Saligenin ROO: 15 min DOA 3-6 hr Receptor: ß2>ß1 |
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levalbuterol
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Trade name: Xopenex (Neb)
Class: Saligenin ROO: 15 DOA: 3-8 hr Receptor: ß2>ß1 |
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formoterol
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Trade name: Foradil
Class: Catecholamine |
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What happens when caecholamines are exposed to heat and light?
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They become inactivated which will cause them to be antagonists or beta blockers. This could have serious consequences in an emergency.
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