Breast Cancer Stagin

Front 1

TX

Back 1

primary tumor can't be assessed

Front 2

T0

Back 2

no evidence of primary tumour

Front 3

Tis

Back 3

Carcinoma in situ

Front 4

Tis (DCIS)

Back 4

ductal carcinoma in situ

Front 5

Tis (LCIS)

Back 5

Lobular carcinoma in situ

Front 6

Tis (Paget's)

Back 6

Paget's disease of nipple with NOT tumor

Front 7

T1

Back 7

tumor 2cm or less in greatest dimension

Front 8

T1mic

Back 8

T1 with microinvasion 0.1cm or less in greatest dimension

Front 9

T1a

Back 9

tumor >0.1cm, but not more than 0.5cm in greatest dimension

(0.1-0.5cm)

Front 10

T1b

Back 10

tumor >0.5cm, but not more than 1cm in greatest dimension

(0.5-1cm)

Front 11

T1c

Back 11

tumor >1cm, but not more than 2cm in greatest dimension

(1-2cm)

Front 12

T2

Back 12

>2cm, but no more than 5 cm in greatest dimension

Front 13

T3

Back 13

tumor >5cm in greatest dimension

Front 14

T4

Back 14

any size with direct extension to chest wall or skin

Front 15

T4a

Back 15

extension to chest wall not including only pectoral muscle

Front 16

T4b

Back 16

edema or ulceration of breast skin, or satellite skin nodules confined to same breast

Front 17

T4c

Back 17

both T4a and T4b

Front 18

T4d

Back 18

inflammatory carcinoma

Front 19

pNX

Back 19

regional lymph nodes cannot be assessed (not removed, or previously excised)

Front 20

pN0

Back 20

no regional LN mets histologically, no additional examination for isolated tumor cells (ITC)

Front 21

pN0(i-)

Back 21

not regional LN nets histologically, negative immunohistochemical (IHC)

Front 22

pN0(i+)

Back 22

no regional lymph node mets histologically, POSITIVE IHC, no IHC >0.2mm (IHC = immunohistochemical)

Front 23

pN0(mol-)

Back 23

no regional LN mets histologically, negative molecular findings (RT-PCR)

Front 24

pN0(mol+)

Back 24

no regional LN mets histologically, positive molecular findings (RT-PCR)

Front 25

pN1

Back 25

mets in 1 to 3 axillary LN and/or in internal mammary nodes with microscopic disease detected by sentinel LN dissection, but none clinically apparent.

Front 26

pN1mi

Back 26

micrometastases (>0.2mm, none >2mm).

Front 27

Stage 0

Back 27

Tis N0 M0

Front 28

Stage IA

Stage IB

Back 28

T1 N0 M0

T0 N1mi M0
T1 N1mi M0

Front 29

Stage IIA

Back 29

T0 N1 M0

T1 N1 M0

T2 N0 M0

Front 30

Stage IIB

Back 30

T2 N1 M0

T3 N0 M0

Front 31

Stage IIIA

Back 31

T0 N2 M0

T1 N2 M0

T2 N2 M0

T2 N2 M0

T3 N1 M0

T3 N2 M0

Front 32

Stage IIIB

Back 32

T4 N0 M0

T4 N1 M0

T4 N2 M0

Front 33

Stage IIIC

Back 33

anyT N3 M0

Front 34

Stage IV

Back 34

anyT anyN M1

Front 35

pN1a

Back 35

Metastases in 1–3 axillary lymph nodes, at least one metastasis >2.0 mm.

Front 36

pN1b

Back 36

Metastases in internal mammary nodes with micrometastases or macrometastases detected by sentinel lymph node biopsy but not clinically detected. (imaging studies or physical examination)

Front 37

pN1c

Back 37

Metastases in 1–3 axillary lymph nodes and in internal mammary lymph nodes with micrometastases or macrometastases detected by sentinel lymph node biopsy but not clinically detected.

Front 38

pN2

Back 38

Metastases in 4–9 axillary lymph nodes.
OR
Metastases in clinically detected internal mammary lymph nodes in the absence of axillary lymph node metastases.

Front 39

pN2a

Back 39

Metastases in 4–9 axillary lymph nodes (at least 1 tumor deposit >2 mm).

Front 40

pN2b

Back 40

Metastases in clinically detectedd internal mammary lymph nodes in the absence of axillary lymph node metastases.

Front 41

pN3

Back 41

Metastases in ≥10 axillary lymph nodes.
OR
Metastases in infraclavicular (level III axillary) lymph nodes.
OR
Metastases in clinically detected ipsilateral internal mammary lymph nodes in the presence of one or more positive level I, II axillary lymph nodes.
OR
Metastases in >3 axillary lymph nodes and in internal mammary lymph nodes with micrometastases or macrometastases detected by sentinel lymph node biopsy but not clinically detected.
OR
Metastases in ipsilateral supraclavicular lymph nodes.

Front 42

pN3a

Back 42

Metastases in ≥10 axillary lymph nodes (at least 1 tumor deposit >2.0 mm).
OR
Metastases to the infraclavicular (level III axillary lymph) nodes.

Front 43

pN3b

Back 43

Metastases in clinically detected ipsilateral internal mammary lymph nodes in the presence of one or more positive axillary lymph nodes;
OR
Metastases in >3 axillary lymph nodes and in internal mammary lymph nodes with micrometastases or macrometastases detected by sentinel lymph node biopsy but not clinically detected.c

Front 44

pN3c

Back 44

Metastases in ipsilateral supraclavicular lymph nodes.

Front 45

NX

Back 45

Regional lymph nodes cannot be assessed (e.g., previously removed).

Front 46

N0

Back 46

No regional lymph node metastases.

Front 47

N1

Back 47

Metastases to movable ipsilateral level I, II axillary lymph node(s).

Front 48

N2

Back 48

Metastases in ipsilateral level I, II axillary lymph nodes that are clinically fixed or matted.
OR
Metastases in clinically detectedb ipsilateral internal mammary nodes in the absence of clinically evident axillary lymph node metastases.

Front 49

N2a

Back 49

Metastases in ipsilateral level I, II axillary lymph nodes fixed to one another (matted) or to other structures.

Front 50

N2b

Back 50

Metastases only in clinically detectedb ipsilateral internal mammary nodes and in the absence of clinically evident level I, II axillary lymph node metastases.

Front 51

N3

Back 51

Metastases in ipsilateral infraclavicular (level III axillary) lymph node(s) with or without level I, II axillary lymph node involvement.
OR
Metastases in clinically detectedb ipsilateral internal mammary lymph node(s) with clinically evident level I, II axillary lymph node metastases.
OR
Metastases in ipsilateral supraclavicular lymph node(s) with or without axillary or internal mammary lymph node involvement.

Front 52

N3a

Back 52

Metastases in ipsilateral infraclavicular lymph node(s).

Front 53

N3b

Back 53

Metastases in ipsilateral internal mammary lymph node(s) and axillary lymph node(s).

Front 54

N3c

Back 54

Metastases in ipsilateral supraclavicular lymph node(s).