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13 Cards in this Set

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  • Back
according to the fick equation, what 4 ways can diffusion rates increase?
increase SA for diffusion
decrease distance (from RBC to tissue)
increase time (decrease velocity)
increase concentration
Poiseuille's equation for Resistance:
R=
thus, Resistance is mostly concerned with ____? Which vessel is responsible for this?
8*length*viscosity / (pi * radius^4)
-changes in radius
-arterioles, as their radius can be adjusted
Cardiac Output
Total Flow. Volume/Time, average is
5L/min
Cardiac Index
Cardiac Output/Body SA
avg is 2.9L/min/m^2.
Conductance
-inverse Resistance, 1/R.
i.e. Conductance = Flow/Pressure.
Resting Pressures: artery, venous, intracardiac
artery: 120/80
vein: 25 -> 0
LV: 120/0
RV: 30/0.
TPR
total peripheral resistance = MAP/CO. TPR is the combined resistance of all systemic BVs (inverse sums)
Pulse Pressure
systolic P - diastolic P.
Mean Arterial Pressure, MAP=Diastolic Pressure + 1/3 (Pulse Pressure).
Where is velocity the lowest? Where are the drastic increases/decreases?
Slowest in capillaries
drastic slowing in small artery/arteriole
drastic speeding in small vein
(chart notes page 12)
write equation relating O2 consumption to blood flow and A-V diffs in [O2]
V O2 = CO ([O2a] - [O2v])

V O2 is O2 consumption. the concentration dif from aa to vv is O2 extraction.
an increased demand for O2 is met by:
increased CO or increased O2 extraction, according to the O2 consumption (V O2) equation
two methods to measure CO
1. Fick Principle: given O2 extraction equation, measure O2 consumption (via breaths) and extraction (via arterial and veinous blood gases)
2. Thermodilution - inject known volume and temperature of cold saline into RA, measure the temp in Pulmonary Artery at certain time intevals, convert to Volume/Time, thus CO
Mean Arterial Pressure =
MAP = CO * TPR. really, CO = (MAP - CVP) / TPR. but CVP~0, so ignore it.