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195 Cards in this Set
- Front
- Back
What are the principal parts of the brain (4)?
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Cerebellum, Cerebrum, Diencephalon, Brainstem
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The thalamus and hypothalamus are located in which part of the brain?
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Diencephalon
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The medulla, pons and midbrain are located in which part of the brain?
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Brainstem
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What is the circle of Willis?
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where arterial blood supply branches in the base of the brain
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How much of the body's daily oxygen and gluclose supply does the brain use?
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20%
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How many minutes of blood flow interruption to the brain to distrupt neuronal function?
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1-2
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How many minutes of blood flow interruption to the brain to cause permanent injury due to lack of oxygen?
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4
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Why must the supply of gluclose to the brain be continuous?
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because carbohydrate storage in the brain is limited.
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What is hypoglycemia and what are the symptoms?
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Gluclose deficiency causes mental confusion, dizziness, convulsions, and unconciousness
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What makes up the blood brain barrier and what is the purpose?
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epithelian cells and astrocytes; protect brain cells from harmful substances and pathogens
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How does the blood brain barrier protect brain cells from harmful substances and pathogens?
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blocks passage of many substances from the blood into the brain tissue, tight junctions seal together epithelial cells and astrocyte processes cover capillaries.
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What are the 3 meninges that cover the brain?
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dura mater, arachnoid mater and pia mater
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What makes up cerebrospinal fluid?
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gluclose, proteins and ions.
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What are the functions of cerebrospinal fluid?
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floats brain and softens impact, optimal ionic concentrations for action potentials, transports nutrients and waste products to and from bloodstream
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Name the ventricles of the brain (4).
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lateral (2), third, fourth
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Describe the lateral ventricles.
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locted in each hemisphere of the cerebrum
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What separates the lateral ventricles?
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septum pellucidum
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Describe the third ventricle.
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narrow cavity superior to the hypothalamus and between the right and left halves of the thalamus
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Describethe fourth ventricle.
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between the brain stem and the cerebellum.
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Where is cerebrospinal fluid produced?
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choroid plexuses
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How is cerebrospinal fluid produced?
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made from blood plasma that leaks out of specialized, tiny blood vessels (capillaries) called choroid plexus and passes through ependymal cells into 4 ventricles.
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choroid plexuses
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located in roof of all four ventricles; consists of tiny capillaries which leak blood plasma into ventricles
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How is cerebrospial fluid reabsorbed?
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through arachnoid villi in the superior sagittal sinus and drains through a median aperture and 2 lateral apertures.
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What is hydrocephalus?
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blockage of drainage of CSF due to many different causes
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Describe the medulla oblongata. (8)
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continuation of spinal cord; ascending sensory tracts; descending motor tracts; nuclei of 5 cranial nerves; cardiovascular center; respiratory center; relays info in and out of cerebellum; reflex centers for coughing, sneezing, swallowig
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What is cranial nerve I?
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olfactory
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What is cranial nerve II?
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Optic
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What is cranial nerve III?
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Oculomotor
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What is cranial nerve IV?
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Trochlear
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What is cranial nerve V?
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Trigeminal
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What is cranial nerve VI?
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Abducens
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What is cranial nerve VII?
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Facial
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What is cranial nerve VIII?
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Vestibulocochlear
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What is cranial nerve IX?
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Glossopharyngeal
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What is cranial nerve X?
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Vagus
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What is cranial nerve XI?
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Accessory
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What is cranial nerve XII?
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Hypoglossal
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Where is the pons located?
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superior to the medulla
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What connects the spinal cord with the brain and links parts of the brain with one another via tracts..
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the pons
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What relays nerve impulses related to voluntary skeletal movements from the cerebral cortex to he cerebellum?
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the pons
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What contains the pneumotaxic and apneustic areas which help control respiration along with the respiratory center in the medulla?
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the pons
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What contains nuclei for cranial nerves V, VI, VII, part of VIII?
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the pons
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What does pneumotaxic and apneustic areas in the pons help control?
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breathing
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Where does the middle cerebellar peduncles of the pons carry sensory info to?
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the cerebellum
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What cranial nerves are located in the pons?
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5-7 and vestibular branch of 8
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What extends from pons to diencephalon?
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Midbrain
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Where is the cerebral aqueduct located?
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midbrain
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What does the cerebral aqueduct connect?
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third and fourth ventricles
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What are cerebral peduncles and where are they located?
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clusters of motor and sensory white fibers which connect the lower and upper brain areas; midbrain
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What is substantia nigra and where is it located?
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helps control subconsious muscle activity located in the midbrain
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What is the red nucleus and where is it located?
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rich blood supply and iron containing pigment located in the mid brain; cortex and cerebellum coordinate muscular movements by sending information here
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What is the corpora quadrigemina and where is it located?
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located on the dorsal surface of the midbrain; coordinates eye movements with visual stimuli and coordinates head movemnts with auditor stimuli
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What formation has scattered nuclei in medulla, pons and midbrain?
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reticular formation
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What is the reticular activating system?
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alerts cerebral cortex to sensory signals to awaken you from sleep (alarms, etc); maintains conciousness & helps keep you awake with stimuli from ears, eyes etc.
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What composes the cerebellum?
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2 serebellar hemispheres and vermis
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What is the function of the cerebellum?
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corrects voluntary muscle contraction and posture, sense of equillibrium
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What is the arbor vitae and where is it located?
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white matter; in cerebellum
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What does the diencephalon surround?
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the third ventricle
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What part of the brain are the thalamus and hypothalamus located?
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diencephalon
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What is a 1 inch long mass of gray matter in each half of the brain?
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Thalamus
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What contains nuclei that serve as relay stations for all sensory impulses,except smell, to the cerebral cortex>
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thalamus
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What registes conscious recognition of pain and temperature and some crude awarenss of light touch and pressure?
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thalamus
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What essential role does the thalamus play?
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Awareness and acquisition of knowledge
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What different roles do the nuclei (regions) of thalamus play?
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relay auditory and visual impulses, taste, somatic sensations; receive impulses from cerebellum or basal ganglia; anterior nucleus concerned with emotions, memory and acquisition of knowledge.
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What is inferior to the thalamus and has four major regions?
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hypothalamus
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What are the four regions of the hypothalamus?
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mammillary, tuberal, supraoptic, preoptic
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What controls many body activities and is one of the major regulators of homeostasis?
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hypothalamus
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What controls the ANS?
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hypothalamus
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What produces hormones but is not an endocine gland?
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hypothalamus
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Hypothalamus
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controls ANS; produces hormones; functions in regulation of emotional and behavioral patterns; regulates eating/drinking through feeding center, satiety center and thirst center; aids in controlling body temp; regulates circadian rhythms and states of conciousness
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What receives somatic and visceral input and is a major regulator of homeostasis?
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hypothalamus
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Where is the pineal gland and habenular nuclei located?
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Epithalamus
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What is the function of the pineal gland and where is it located?
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secretes melatonin during darkness and promotes sleepiness and sets biological clock; located in epithalamus
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What is the function of the habenular nuclei and where is it located?
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emotional response to odors; located in the epithalamus
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What does the corpora quadrigemina consist of?
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superior and inferior colliculi
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Superior colliculi
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reflex center involved in eye, head and neck movements with visual stimulation; part of the corpora quadrigemina
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Inferior colliculi
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reflex center involved in head and trunk movements with auditory stimuli; part of the corpora quadrigemina
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What partof the brain is the largest nd the "thinking" part?
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cerebrum
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What is the gray matter of the cerebrum called?
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cerebral cortex
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This contains billions of cells and is 2-4 mm thick. (cerebrum)
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cerebral cortex
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Contains gyr and sulci.
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cerebral cortex
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Gyri
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folds of the cerebral cortex as a result of quick growth
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Sulci
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grooves of the cerebral cortex
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What separates the left and right hemispheres of the cerebral cortex?
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longitudial fissure
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What connects the left and right cerebral hemispheres?
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corpus callosum
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What is the corpus callosum?
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band of white matter connecting left and right cerebral hemispheres
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What are the four lobes of each cerebral hemisphere?
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frontal, parietal, temporal and occipital
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This is the fifth part of the cerebrum, but is not a lobe.
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insula
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this lies deep to the parietal, frontal and temporal lobes and cannot be seen in an external view of the brain.
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insula
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What are association fibers in the white matter under the cortex?
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they connect and transmit nerve impulses between gyri in the same hemisphere.
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What are commissural fibers in the white matter under the cortex?
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they connect gyri in one cerebral hemisphere to the corresponding gyri in the opposite hemisphere.
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What are projection fibers in the white matter under the cortex?
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they form ascending and descending tracts that transmit impulses from the cerebrum to other parts of the bran and spinal cord.
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What does the white matter in the cerebrum consist of?
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myelinated axons running in three directions; association fibers, commissural fibers, projection fibers
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What is the basal ganglia and where is it located?
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paired masses of gray matter located in each cerebral hemisphere.
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What controls large automatic movements of skeletal muscles ad serves as input/output to/from cerebral cortex, thalamus and hypothalamus?
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basal ganglia
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Where is the limbic system located?
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in the cerebral hemispheres and diencephalon
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What is the limbic system?
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emotional brain; functions in emotional aspects of behavior and memory; strong emotions can strenghten memory
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Is the cerebral cortex white or gray matter?
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gray
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What are the sensory areas of the cerebral cortex concerned with?
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reception and interpretation of sensory impulses.
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What are some important sensory areas of the cerebral cortex (4)?
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primary.....somatosensory (touch), visual, auditory and gustatory (taste) areas
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What are the important motor areas of the cerebral cortex (2)?
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primary motor area, Broca's speech area
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What are the association areas of the cerebral cortex concerned with?
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complex integrative functions such as memory, emotions, reasoning, will, judgement, personality traits, and intelligence
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Somatosensory area of the cerebral cortex
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integrate and interpret touch
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Visual association area of the cerebral cortex
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recognize and evaluate visual info
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Auditory association area of cerebral cortex (Wernicke's)
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words become speech
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Gnostic area of cerebral cortex
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integrates all senses and responds
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Premotor area of cerebral cortex
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learned skilled movements such as typing
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Frontal Eye Field area of cerebral cortex
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scanning eye movements such as a phone book
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Where are lanquage areas located in the brain?
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in the left cerebral hemisphere of most people
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Aphasia
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inability to use or comprehend words
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nonfluent aphasia
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inability to properly form words due to damage in broca's speech area (stroke)
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fluent aphasia
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faulty understanding of spoken or writte words due to damage to common integrative area or auditory association area
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word deafness
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an inabiity to understand a spoken word due to damage to commaon integrative area or auditory association area
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word blindness
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an inability to understand written words due to damage to common integrative area or auditory association area
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Which hemisphere is more important for right handed control, spoken and written language and numerical and scientific skills?
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Left hemisphere
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Which hemisphere is more important for left handed control, musical and artistic awarenss, space and pattern perception, insight, imagination, and generating mental images of the senses?
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Right hemisphere
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Damage to which hemisphere causes aphasia?
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Left hemisphere
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Damage to which hemisphere causes speech with little emotional inflection?
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Right hemisphere
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What is a tracing of electrical impulses of the brain?
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EEG - electroencephalogram
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What s the criterion in confirming brain death?
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complete absence of brain waves in two EEG's taken 24 hours apart
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What are brain waves?
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millions of nerve action potentials in cerebral cortex
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What do the four lines in the EEG represent?
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Alpha - awake and resting
Beta - mental activity Theta - emotional stress Delta - deep sleep |
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Olfactory Nerve I
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sense of smell; sits in cribaform plate
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Optic Nerve II
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connects to retina; vision
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Oculomotor Nerve III
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controls muscles that move eyelids and eyeballs, controls accomodation for near vision, constricts pupil
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Trochlear Nerve IV
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controls superior oblique eye muscles
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Trigeminal Nerve V
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motor portion controls muscles of mastication (chewing); sensory portion touch, pain, temp receptors of the face
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Abducens Nerve VI
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controls lateal rectus eye muscles
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Facial Nerve VII
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motor portion controls facial muscles, salivary, nasal, and oral mucous glands and tears; sensory porton taste buds on anterior of tongue
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Vestibulocochlear Nerve VIII
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enables hearing; has two branches= cochlear and vestibular
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Glossopharyngeal Nerve IX
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activates the muscle that lifts throat during swallowing, activates secretios of parotid gland, taste on posterior of tongue
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Vagus Nerve X
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receives sensations for viscera, controls cardiac and smooth muscle; controls secretion of digestive fluids
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Spinal Accessory Nerve XI
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has two portions = cranial and spinal; activates skeletal muscles of throat and soft palate; activates sternocleidomastoid and trap muscles
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Hypoglossal Nerve XII
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controls muscles of tongue during seech and swallowing
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What happens to our nervous system as we age?
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brain weight declines, # of synaptic contacts decline, diminished info processing, conduction velocity decreases, voluntary motor movements and reflexes slow down,
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CVA
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cerebrovascular accident or stroke
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Two classifications of CVA's
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ischemic - decreased blood supply to brain
hemorrhagic - burst blood vessel in brain |
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t-PA
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tissue plasminogen activator - used within 3 hrs of ischemic CVA onset can decrease permanent disability
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TIA
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transient ishemic attack = temporary cerebral dysfunction
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Alzheimers Disease (AD)
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a form of dementia; great loss of neurons in specific regions like hippocampus and cerebral cortex, loss of neurons that release aCH, amyloid plaques, tangled protein filaents develop within neurons and destroy them, no cure
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Concusion
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temporary loss of conciousness
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Contusion
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brusing of the brain, > 5 min unconciousness but blood in CSF
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Alzheimers Disease (AD)
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a form of dementia; great loss of neurons in specific regions like hippocampus and cerebral cortex, loss of neurons that release aCH, amyloid plaques, tangled protein filaents develop within neurons and destroy them, no cure
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Concusion
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temporary loss of conciousness
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Contusion
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brusing of the brain, > 5 min unconciousness but blood in CSF
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The autonomic motor pathways consist of what?
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2 motor neurons that communicate at the autonomic ganglion
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Describe the preganglionic neuron of the ANS
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it has its cell body in the brain or spinal cord and is myelinated
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Describe the postganglionic neuron of the ANS
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is has it cell body outside the CNS and is unmyelinated and terminates in a muscle or a gland (visceral effector)
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What are the 2 major divisions of the ANS?
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sypathetic or parasympathetic
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Sympathetic Division of ANS
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"fight or flight"; speeds organs up
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Parasympathetic Division of ANS
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"rest and digest"; decreases heart rate
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Contains vital centers that regulate heartbeat, breathing, blood pressure, vomitting, coughing?
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Medulla Oblongata
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Smoothes and coordinates skilled skeletal muscle movement; also posture and balance or equilibrium?
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cerebellum
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Controls and integrates the autonomic nervous system, regulates hormones, emotional behavior, temp, eating & drinking behavior?
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hypothalamus
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interprets sensory input, controls skilled skeletal muscle movements and is involved in emotional and intellectual processes?
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cerebral cortex
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Helps control breathing; conducts impulses to and from the cerebellum, midbrain, and medulla
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pons
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Relays all sensory iput to the cerebral cortex; involved in skeletal muscle actions and memory processing?
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thalamus
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Coordinates visual and auditory reflexes?
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Corpora Quadrigemina
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Coordinates gross, automatic muscle movements; also involved in the limbic system?
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Basal Nuclei
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White fiber tracts communicating between hemi-spheres?
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Corpus Callosum
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The components of the autonomic reflex arc are:
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sensory receptor, sensory neuron, integrating center, 2 motor neurons, effector
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The components of the somatic reflex arc are:
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sensory receptor, sensory neuron, integrating center, 1 motor neurons, effector
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Where are the autonomic integrating centers?
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The hypothalamus and lateral gray horn of spinal cord.
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Are the autonomic integrating centers polysynaptic or monosynaptic?
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Polysynaptic
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Where are the cell bodies for the sympathetic preganglionic neurons located?
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in the gray matter of the 12 thoracic and first three lumbar segments of the spinal cord
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Where are the cell bodies for the postganglionic neurons located?
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in the sympathetic trunks or vertical chains along both sides of vertebral column or are bundled in collateral ganglia that lie anterior to the spinal column and close to large abdominal arteries
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Name the postganglionic neurons.
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Celiac, superior mesenteric, inferior mesenteric
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Where is the cell body in the preganglionic neuron located?
Is it myelinated or unmyelinated? |
in th brain or spinal cord; myelinated
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Where is the cel body in th postganglionic neuron located? Is it myelinated or unmyelinted?
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outside of the CNS and it terminates in visceral effector (muscle or gland)
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What are the two divisions of the autonomic nervous system?
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Sympathetic and Parasympathetic
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Sympathetic Division
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fight or flght; speeds up organs
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Parasympathetic Division
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rest and digest; slows organs down
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What are the sympathetic trunk ganglia functions?
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innervate organs above diaphragm (pineal glad, lacramal glands, salivary glands, mucosa of the nose and palate, eyes, heart, lungs
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What are the collateral ganglia functions?
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celiac ganglion, superior mesenteric, inferior mesenteric
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Celiac ganglion are connected to........
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liver, stomach, adrenals
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Superior Mesenteric ganglion are connected to.........
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small itesting, ascending and transverse colon
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Inferior Mesenteric ganglion are connected to.........
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descending colon, kidney, bladder, reproductive organs
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Divergence
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many organs can get turned on at once; each preganglionic cell synapses on many postganglionic cells that go to effectors; multiple organs fet the message at the same time
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Adrenal glands
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What are modified clusters of postganglionic cell bodies that release epinephrine and norepinephrine into blood.
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Preganglionic cell bodies in thoracic and first 3 lumbar segments of spinal cord
Postganglionic cell bodies (ganglia) - sympathetic trunk ganglia chain near vertebral column - prevertebral ganglia near large blood vessel in gut (celiac, superior mesenteric, inferior mesenteric) |
Sympathetic Division
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- Preganglionic cell bodies in nuclei of 4 cranial nerves and the sacral spinal cord
Postganglionic cell bodies (ganglia) - very near or in wall of organ |
Parasympathetic Division
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What are autonomic plexes?
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tangled networks of sympathetic and parasympathetic neurons which lie along major arteries
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What are the two classifications for ANS neurons? Why are they classified this way?
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Cholinergic or Adrenergic
based on neurotransmitter they release. |
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Adrenergic Neurons release what and from where?
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They release Norepinephrine from postganglionic sympathetic neurons.
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Adrenergic Receptors accept what?
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Norepinephrine and epinephrine
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Adrenergic receptors on effectors are what based on what?
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excited or inhibited based on what type of receptor the organ has
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What are the main types of adrenergic receptors?
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Alpha 1 and Beta 1 - excite effector
Alpha 2 and Beta 2 - inhibit effector |
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What does cholinergic neurons release?
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aCH
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Do cholinergic neurons excite or inhibit?
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depends on type of receptor the effector organ has
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What are the two types of cholinergic receptors?
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Nicotinic and Muscarinic
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Activation of nicotinic receptors cause what?
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excitation of postsynaptic cell
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Activation of muscarinic receptors causes what?
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either excitation or inhibition depending on the cells receptors
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Agonist
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is a substance that binds to and activates a receptor, mimicking the effect of a natural neurotransmitter or hormone
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Antagonist
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is a substance that binds to and blocks a receptor, preventing a natural neurotransmitter or hormon from exerting its effect.
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SLUDD
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salivation, lacrimation, urination, digestion and defacation = maintained by parasympathetic system
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