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40 Cards in this Set

  • Front
  • Back
What are the 3 types of encapsulated and non-encapsulated receptors? Which as rapidly adaptive (RA) and which are slowly adaptive (SA)?
Which 2 are superficial (*)?
Encapsulated:
- Meissner's * (RA)
- Pacinian (SA)
- Ruffini (SA)
Non-Encapsulated:
- Merkel axon terminals * (RA)
- Hair cell receptors
- Bare/Naked/Free Nerve endings
Generally speaking, what type of sensory nerve fiber will have tactile, low threshold mechanoreceptors?
All the encapsulated fibers and hair cell receptors will carry tactile information using low threshold mechano receptors.
What types of sensory nerve fibers will carry nocioception and temperature?
Non-encapsulated, naked nerve endings (Bare & Merkel)
What can you say about the distribution of nerve fibers in relation to their field size?
The smaller the field size the denser the distribution of the nerves. Thus areas with ++ dense nerves (hand, mouth genitals) will have very good discrimination.
What type of fiber (in a mixed motor/sensory nerve) would fire the fastest?
Put the remaining 3 types of fibers in order of descending conduction speed.
Aa or Type I fibers have the biggest diameter and fire the fastest (carry the stretch reflex)
II (AB), III (Ad) and IV (C) <-- only unmyelinated type, gamma fibers that tighten muscle spindles, detect nocioception in sensory fibers.
How has the nervous system encoded each of the following:
1. Intensity
2. Location of stimulus
3. Modality (ie touch, temp, etc)
4. Quality (ie warm & smooth)
1. Intensity - frequency of AP's
2. Location of stimulus - receptive field that an axon is coming from
3. Modality (ie touch, temp, etc) - type of axon (each axon carries only 1 modality)
4. Quality (ie warm & smooth) - population of axons that are firing
Define each vision condition and list the type of lens required:
Emmetropia
Myopia
Hypermetropia
Astigmatism
Emmetropia - normal; no lens needed

Myopia - rays focus in front of retina (nearsighted). Nee Concave lenses

Hypermetropia - rays focus behind the lens (farsighted) need convex lens

Astigmatism - rays do not focus on fovea, need a bent lens to redirect the rays
What are the contents of the anterior segment of the eye?
cornea
sclera
anterior chamber
Iris (& pupil)
Ciliary body
Lens
Identify the structures
The sclera is a white collagenous structure that surrounds the eye. What covers it? What is it perforated by?
Function (2)?
The sclera is covered by the cornea and episclera. It is perforated posteriorly by the optic nerve, at the lamina cribosa.
Functions:
1. insertion of extraocular muscles
2. blocks extraneous light from entering the globe
The conjuNctiva is a modified ______ that covers the ______. It is a very vascular tissue with 2 functions:
-
-
The conjunctiva is a modified mucous membrane that covers the SCLERA. It is a very vascular tissue with 2 functions:
- PROTECTS THE GLOBE
- PRODUCES PART OF TEAR FILM
* conjuctiva = nonkeratinized, stratified squamous columnar epithelium w/goblet cells
What is the episclera?
A vascular plexus between the conjunctiva and the sclera. It has 2 layers of vessels; superficial and deep.
What 3 things make the cornea clear? What nerve supplies it's sensation?
Cornea is clear because:
1. Avascular
2. uniform strucuture
3. Has ATP pumps in the endothelium (deep to Descemet's Membrane) that keep it dehydrated
Nerve supply: Ophthalmic division of Trigeminal nerve (V1).
What are the 5 layers of the cornea?
1. Epithelium - nonkerat stratified squamous, acts as a barrier & can regenerate

2. Bownman's membrane

3. Stroma: >90% of total thickness, orderly array of collagen, will not regenerate

4. Desecemet's Membrane

5. Edothelium: monolayer; contain ATP pumps to keep cornea dehydrated
Which is opaque, the cornea or the sclera? Why (i.e. what makes it opaque?)
The sclera is opaque and the cornea is clear. This is b/c the sclera has coarse & irregular collagen while the cornea has fine & regularly arranged collagen.
What is the innervation of the Iris constrictor muscles? Dilators?
What is the NT for each?
Spincter muscle constrictors: parasympathetics, CN III, Cholinergics

Iris dilator muscles:
Sympathetics, adrenergics
Have a good look at this picture and note the layers of things
The cilliary body is a ring-like structure located behind the iris. It is very vascular. What are it's 2 functions?
Cilliary body functions:
1. production of aqueous humor (from the 2-layered epithelium which nourishes avascular structures (cornea/lens)
2. Accomodation of lens - contraction makes lens round and allows it to focus on near things
Where is aqueous humor made, how does it circulate and where is it drained?
Aqueous humor is made by the cilliary body. It circulates from the posterior chamber, through the pupil to the anterior chamber. It is then drained by the trabecular meshwork --> canal of Schlem --> episcleral venous vessels --> systemic veins
What is the angle of the eye (ie what structures form it & what does it do?)
The angle is formed where the Iris meets the Cornea.Fluid drains here through the trabecular meshwork (if obstructed - get Glaucoma and rising intraocular pressure).
The "near triad" allows you to see things close-up. What does this triad involve?
1. Lens accomodation - makes it round to converge the rays of light
2. Eyes converge to keep the near object centered on the fovea
3. Pupils constrict to decrease spherical abberation
What are the 3 main types of cataracts? What conditions are associated with the last 2 causes?
1. Cortical

2. Nuclear sclerosis - aging

3. Posterior subcapsular - steroids, diabetes
What are the 4 components of the posterior segment?
1. Vitreous
2. Retina
3. Choroid
4. Optic Nerve
The Retina has 10 layers. The inner-most of which is called the retinal pigment epithelium (RPE). What are 2 functions of the RPE?
1. forms the blood-brain barrier
2. Supports metabolism of photoreceptors.
Sits on top of the ++ vascular choroid and is impenetrable to light!
What is the function of the choroid?
The choroid supplies the outer retina with much of its metabolic requirements (esp. important b/c centre of the fovea is avascular)
What is found in each of the following holes:
- optic foramen
- superior orbital fissure
- inferior orbital fissure
- optic foramen: (in sphenoid bone) optic nerve and ophthalmic artery
- superior orbital fissure: (between G & L wings of sphenoid) contains CN III, IV, V1, VI & vessels
- inferior orbital fissure: sympathetics & vessels
What nerve and muscle are responsible for:
- lid closure
- lid opening
Lid closure
-orbicularis oculi; CN VII

Lid opening:
- Levator palpebrae superiorus; CN III
- Mullers muscle; sympathetics
List the 3 layers of the tear film from the corneal epithelium outwards. For each layer list the origin and function.
1. Mucin layer - conjuctival goblet cells; aids in adherence to cornea
2. Aqueous layer: accessory lacrimal glands; forms the bulk of tear film
3. Lipid layer: meibomian gland on lid margin; reduces tear evaporation
Which gland is responsible for producing reflex secretions in response to irritation, emotion or bright light?
The lacrimal gland ( innervated by CN II)
* the accessory gland provides basal secretions
For each of the following muscles list it's CN and action (movement):
Lateral Rectus
Medial Rectus
Superior Rectus
Inferior Rectus
Inferior oblique
Superior oblique
LR - aBduction; CN 6
MR - aDduction; CN 3
SR - elevation; CN 3
IR - depression; CN3
IO - down & in; CN 3
SO - Up & in; CN 6
What is the effect of a CN 3 palsy? CN 2?
CN 3 palsy:
- diplopia
- ptosis
- dilated pupil
CN2:
- decrease acuity, loss of color vision and visual field defects
What is the difference in a CN IV and a CN VI palsy?
They both will cause diplopia but with a CN 4 the eye will be down and out and with CN 6 the eye will have medial deviation.
What would be the signs of a CN V and VII lesion?
CN V:
Corneal anaesthesia (leading to ulcers)

CNVII:
- Ptosis (failure of lid closure)
- tearing on face
- ulceration d/t inability to protect the eye
Review the production, circulation and drainage of aqueous humor.
What is Schwalbe's line? Schlemm's canal?
Anterior chamber depth is important!! < 20 deg = narrow!!
Schwalbe's line: found on the interior surface of the cornea, and delineates the outer limit of the corneal endothelium layer (termination of Descemet's membrane).
Schlemm's canal: in front of scleral spur, encircles the eye and drains humor to ciliary veins.
List the muscles and nerves involved in the pupillary light response.
1. Iris spincter muscle (smooth ring-shaped & flat) is supplied by parasympathetics, and it constricts the iris (miosis - opiods)
2. Iris dilator muscle, extend to 0,3mm of the pupillary border and is supplied by sympathetics (mydriasis - cholinergics)
The ciliary body consists of what 2 things?
smooth muscle fibers which give rise to the lens zonules and ciliary processes which secrete the aqueous humor.
anterior portion = par plicata
posterior portion = pars plana
Moving towards the vitrous humor, what are the 4 layers of the choroid?
Suprachoroid
vascular layer & Chorio capillaries
Brush's membrane
Moving towards the inside of the eye (vitrous humor) what are the 3 layers of the outer retina? What is it's blood supply?
RPE - sticks to Bruch's membrane
Rods & cones -
Outer plexiform layer - axons of R & C that synapse with dendrites of bipolar cells
Blood supply is the choriocapillaries (under the RPE)
Moving from the middle of retina to the vitrous humor what are the 4 layers of the inner retina? What is it's blood supply?
1. Inner nuclear layer - cell bodies (of bipolar, horizontal & amacrine cells)
2. Inner plexiform layer - synapses of bipolar, amacrine and ganglion cells
3. Ganglion cell layer
4. Nerve fiber layer (no myelin!)
Blood supply = Central retinal artery & vein
What is the blood supply to the optic nerve?
short posterior ciliary arteries & central retinal artery