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300 Cards in this Set
- Front
- Back
Which one of these is not one of the "big ideas" of the course?
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The brain is composed of neurons.
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Frontotemporal dementia, Corticobasal degeneration, Alzheimer's and a growing list of other diseases appear to be caused by
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Genetic mutations
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Not recognizing part of your body as belonging to you is referred to as
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alien hand syndrome
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The neuroaxis refers to the same structures as
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The central nervous system
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Descartes was
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a dualist
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The neuroanatomical term synonymous with "towards the nose" is
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rostral
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The plane of section that divides the body into left and right halves is
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sagittal
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The pane of section that divides the body into top and bottom halves is
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horizontal
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Homo sapiens coexisted with
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neanderthals
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The hypothesis that the psyche is responsible for behavior was expounded by
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Aristotle
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The study of how genetic expression is related to the environment and experience is known as
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epigenetics
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Humans are most closely related to
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chimpanzees
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The radiator hypothesis is a theory relating to
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cooling of the brain by blood flow
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Which one of the following is not correlated with brain size?
health, cause of death, age, intelligence, body size |
intelligence
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Motor output signals are sent through layer(s) _______ of the cortex.
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V and VI
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If we are speaking of the brain, "dorsal" means
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toward the top of the skull
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The neuroanatomical direction that means "toward the middle" is
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medial
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The plane of the section the divides structures into front and back is
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coronal or frontal
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In the PNS, sensory nerves enter the spinal cord through the
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dorsal
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The part of the nervous system that rests, restores and rebuilds the body is the
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parasympathetic branch of the ANS
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The outermost of the three meninges is the
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dura mater
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Blood capillaries travel through the space beneath the
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arachnoid layer
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Arachnoid granulations allow the passage of
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cerebral spinal fluid
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A ridge of "up folding" of the cortical surface is called a
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gyrus
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A valley or "down folding" of the cortical surface is called a
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sulcus or fissure
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In most people, the ability for language is found
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in the left hemisphere
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The structure that connects the two cerebral hemispheres is the
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corpus callosum
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The primary motor cortex is found in the
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frontal lobe
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The primary motor cortex is found on the
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pre-central gyrus
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Based on what you've read in the text and listened to in class, the "ghost" or "phantom" limb phenomenon is most probably caused by neurological activity in the
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parietal lobe
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The primary visual cortex is located in the
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occipital lobe
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The primary somtaosensory cortex is located in the
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parietal lobe
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Circuits in the fusiform gyrus are responsible for
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facial recognition
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In capgras delusion, a person
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thinks a familiar person or object has been replaced with an exact duplicate
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Parkinson's disease is caused by a lack of ________ input.
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dopaminergic
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The "starter/stopper" motor for movements is the
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basal ganglia
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The occipital lobe
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back of the brain
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The location of the primary motor cortex
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temporal lobe
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The cerebellum
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bottom of the brain
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The location of facial recognition
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temporal lobe
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The brain region that controls vomiting.
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area postrema
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The brain region that acts as a relay for sensory information coming form the periphery and heading on the primary sensory cortices.
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Thalamus
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the brain region that controls recognition of - and responses to - threatening or fearful stimuli
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amygdala
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The brain region that control autonomic functions such as osmotic balance and reproductive behaviors
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hypothalamus
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In the human brain the basal ganglia, limbic system, and olfactory bulbs are considered part of the...
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telencephalon
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the golgi stain made use of ______ to stain neurons so they could be viewed under a microscope.
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silver nitrate
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The cell's soma
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the part with the nucleus, the head
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The place that acts as an "outlet strip" to allow more places for other neurons to "plug in" to the neuron
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dendrites
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The dendrites
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the long projections
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According to Professor Clark, social position in Europe during the Middle Ages was NOT strongly influenced by which of the following?
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race
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Spartacus was
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White
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Septimus Severus was
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black
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Egyptian tomb paintings are of interest to the discussion we have been having recently because
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there is no relationship between skin color and social position in the paintings
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The first use of the word "race" in English occurred
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Between Columbus' arrival on Hispanola and the American Revolutionin 1776
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The doctrine of discovery
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gave Papal blessing to making slaves of non-Christians and taking their land
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Professor Clark argued that the Jim Crow laws were created because of
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a desire to preserve cheap labor by denying Blacks opportunities to pursue better jobs
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According to Prof. clark, racism is just part of "human nature". T or F
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False
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Blacks have an extra muscle in their legs. T or F
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false
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According to Prof. Clark, BiDil, a drug for heart disease
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was originally prescribed for people of all races, but was reinvented as a "for-Blacks-only" when the original patent was about to expire.
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In the first half of the 20th century, many professional basketball players were
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Jewish
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Skin color, facial features, and hair color and texture are largely genetically determined. T or F
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True
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Polygenic inheritance for skin color means that people with dark skin have alleles that are not found in people with light skin. T or F
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False
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Over two hundred years of race science in the United State has produced a combination of genetic, physiological and anatomical traits that uniquely and conclusively identifies members of all racial groups. T or F
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False
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The reason race is not a biological concept is because race mixing over the last few centuries has diluted the original pure races. T or F
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False
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Physiological (Mechanism/ Causation)
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a behavior is related to brain activity and the reactions that occur there (example: certain chemical reactions allow hormones to influence brain activity)
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Ontogenetic (Development)
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a behavior develops through the influence of genes, nutrition, experience, and other interactions (example: the ability to stop impulses develops from birth to adolescence, showing gradual maturation of the brain's frontal lobe)
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Biological explanations of behavior
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-physiological
-ontogenetic -evolutionary -functional |
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Evolutionary (Phylogeny)
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a behavior or structure relates to its evolutionary history (example: goose bumps are now useless to humans because our arm hair is so short, but the behavior evolved from our ancient ancestors)
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Functional (Adaptation)
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the reason why a behavior or structure evolved as it did; identifies genetic advantage (example: certain animals use camouflage as protection against predators)
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Dualism
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-Descartes
-behavior is controlled by mind and body -mind receives info from the body through the brain -mind directs body through brain |
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Rene Descartes
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-suggested that the mind works though the pineal body (now pineal gland)
-mind instructs the pineal body to direct fluid form the ventricles through nerves and into muscles -fluid expands the muscles, the body moves |
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Monism
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-only one kind of existence
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Genes
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-units of heredity that maintain structural identity from one generation to another
-segments of DNA that encode the synthesis of particular proteins |
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Chromosomes
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-genes are inside chromosomes
-the double-helix structures that hold an organism's entire DNA sequence -like blueprints -contain thousands of gene |
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DNA
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-template for RNA
-capable of replicating and determining the inherited structure of a cell's proteins |
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Translation of RNA
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-structural proteins or enzymes
-DNA uncoils to expose a gene -one strand of the gene serves as a template for transcribing a molecule of mRNA -mRNA leaves the nucleus and comes in contact with ribosomes in the endoplasmic reticulum -as a ribosome moves along the mRNA, it translates the bases into a specific amino acid chain, which forms the protein |
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Homozygous
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-having two identical alleles for a trait
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Recessive
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-effects only in homozygous condition
-routinely unexpressed allele - |
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sex-linked
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-most sex-linked on X chromosome
-recessive gene for red-green color vision deficiency |
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sex-limited
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-genes activated by sex hormones
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autosomal genes
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-contain the genes that contribute most to our physical appearance and behavioral functions
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X chromosome
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-genes for 1500 proteins
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Y chromosome
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-genes for only 27 proteins
-some sites influence genes on other chromosomes |
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Monozygotic
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-from one egg
-identical twins |
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Dizygotic
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-from two eggs
-fraternal twins |
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Adopted children
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-resemblance to biological parents suggest high heritability
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A notochord is
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a longitudinal flexible rod in the back
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A person who can display some rudimentary behaviors such as smiling or blinking but is otherwise not conscious is described as being
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in a minimally conscious state
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All the nerve processes radiating out beyond the brain and spinal cord as well as all the neuronsoutside the brain and spinal cord constitute the
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peripheral nervous system
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Dunbar proposed that group sizes of about _____ tend to be correlated with increased brain size in primates.
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150
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Homo sapiens coexisted with
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Neanderthals
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Humans are most closely related to
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chimpanzees
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Humans, monkeys, Neanderthals, and chimpanzees all belong to the same
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order
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Insects have
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enough ganglia to be called a brain
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Modern humans appeared approximately
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200,000 years ago
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More advanced nervous systems often have similar structures on the left and right sides (e.g., theleft and right hemispheres of the brain). This concept is known as
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bilateral symmetry
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Of the 100,000 people in the United States who may become comatose in a given year, how manyrecover consciousness?
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20 percent
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Other than humans, which chordate has the largest forebrain?
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birds
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Our small face, vaulted cranium, upright mobility, and distribution of hair are features that link us with juvenile chimps. This illustrates
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neoteny
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Potts proposed that climate change may have placed pressure on apes to adapt to their environment.Specifically, he proposed that apes that lived in _____ climates may have begun to walk upright.
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drier
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The _____ is a nonmaterial entity that is responsible for intelligence, attention, awareness, and consciousness.
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mind
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The brain uses ____ of the body’s oxygen and _____ of the body’s glucose.
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25 percent; 70 percent
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The correct order of the evolution of nervous systems from simple to complex is
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nerve net, segmentation, ganglia, spinal cord, brain
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The first primate to walk upright similar to humans was
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Australopithecus
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The human spinal cord is a great example of the concept of
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segmentation
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The notion that all behavior can be explained by the workings of the brain is commonly referred to as
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materialism
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The notion that the mind resides in the pineal body comes from
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Descartes
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The notion that the movements we make and the movements we perceive in others are central to communication with one another is called the theory of
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embodied language
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The oldest fossils that have been identified as human are approximately
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2 million years old
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The postulation that we make subliminal movements of our larynx and muscles when we imaginewas expounded by
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Edmond Jacobson
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The study of how genetic expression is related to the environment and experience is known as
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epigenetics
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Vegetation eaters have
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smaller brains than fruit eaters
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Which of the following is a conclusion that is necessitated by materialism?
. Because all animal species are related, their brains must also be related. . Because all animal species are related, their behavior must also be related. . The brains of complex organisms like humans evolved from the brains of simpler organisms. . All of the answers are correct. |
All of the answers are correct.
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Which of the following is not correlated with brain size?
. health . cause of death . age . intelligence |
intelligence
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Which of the following statements is most accurate?
. Nonhuman animals have mostly inherited behavior and are little influenced by learning. . Humans share many inherited behaviors but are mostly influenced by learning. . Unlike nonhuman animals, humans share very few inherited behaviors and are mostlyinfluenced by learning. . Unlike nonhuman animals, humans’ behavior is totally learned. |
Humans share many inherited behaviors but are mostly influenced by learning.
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“Behavior consists of patterns in time” is a definition of behavior expounded by
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Edmond Jacobson
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A hemorrhagic stoke is caused by
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a ruptured blood vessel
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Awaking from sleep is a function of
|
the reticular formation
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Cortical regions
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have different specific chemical characteristics
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Fiorito and Scotto (1992) attempted to train an octopus to associate a red ball with a reward and a white ball with a mild electric shock. Results of this study demonstrated that
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the octopus quickly learned to distinguish between the two colored balls, and another octopus was able to learn the same association though observation
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If a tree falls in the forest, does it make a sound if no one is present?
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No, because sound is a fabrication of your brain
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In the human brain the basal ganglia, limbic system, and olfactory bulbs are considered part of the
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telencephalon
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In the human brain the mesencephalon contains:
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tectum and tegmentum
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Ipsilateral is to contralateral as:
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same is to opposite.
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Ischemic stroke is caused by:
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a clot
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Language is usually localized in:
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the left hemisphere.
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Motor output signals are sent through layer(s) _____ of the cortex.
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V and VI
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Parkinson's disease and Tourette's syndrome are neurological diseases associated with the:
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basal ganglia
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Rostral is to caudal as:
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anterior is to posterior
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Sensory inputs are transmitted through layer(s) ______ of the cortex.
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IV
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The _____ nervous system works to help us "rest and digest," whereas the _____ nervous system helps initiate fight-or-flight responses.
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parasympathetic; sympathetic
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The basal ganglia primarily control:
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voluntary movement.
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The functions of the temporal lobes are mainly:
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hearing, language, and music.
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The hippocampus and the amygdala are part of:
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the limbic system
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The hippocampus and the cingulate cortex have been implicated in;
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memory
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The hypothalamus is not primarily involved in:
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sensory input
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The lateral geniculate nucleus deals with:
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vision
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The law of Bell and Magendie states:
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the dorsal spinal cord is sensory and the ventral is motor.
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The left hemisphere primarily controls functions on the _____ side of the body.
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contralateral
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The primary function of the thalamus is:
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transmission of sensory inputs to the cortex.
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The thalamus and hypothalamus are considered part of the:
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diencephalon
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The vagus, facial, and oculomotor nerves are the primary component of:
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the parasympathetic nervous system.
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There are _____ pairs of cranial nerves.
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12
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Tissue plasminogen activator (t-PA) is effective for treating:
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ischemic stroke.
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Which of the following is not part of the forebrain?
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the tectum
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______ refers to the nervous system's ability to change and adapt to compensate for injury.
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Neuroplasticity
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Based on their observations of stained neurons, Golgi put forward the ______ hypothesis, whereas
Cajal proposed the ______ hypothesis. |
nerve net; neuron
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Because the gene that leads to Huntington’s disease is dominant, a child who has one parent with
Huntington’s disease has a _____ chance of developing the disorder. |
50%
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Chris has been feeling very ill lately. He has had a severe headache for a week now and has been
vomiting, has had trouble concentrating, and has started losing some of his vision. This morning he had a seizure. You tell Chris he should go to the hospital immediately because he probably has: |
a brain tumor
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Greg accidentally cuts his fingertip with a knife. The next day he notices that his fingertip seems
numb to the touch. Greg is very concerned about this, but you tell him not to worry because: |
nerves in the PNS regenerate thanks to Schwann cells.
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Melissa, a 23-year-old female living in Alaska, has been having tingling sensations in her right arm
and leg for a few weeks. Today when she woke up she realized that she could barely move her right arm. She had a similar set of symptoms a couple of years ago, but they went away, so she thought everything was fine. Your advice to Melissa is to go to the doctor because: |
she may have multiple sclerosis.
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The notion that two individuals with the exact same genes could end up developing differently is
explained by: |
phenotypic plasticity.
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Which of the following is not one of the ways in which epigenetic mechanisms can influence the
expression of a particular gene? |
ribosome modification
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______ is a term that means having two different alleles for the same trait.
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Heterozygous
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A chain of amino acids forms a:
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protein
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A child who has seizures, blindness, and degenerating motor and mental ability and who dies at an
early age most likely has: |
Tay-Sachs disease.
|
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According to the text, which of the following statements is correct?
about glial cells and neurons cells |
Both some new neurons and many new glial cells are formed throughout life.
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An analogous term for receptor is:
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keyhole
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Astroglia are not associated with:
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removal of dead tissue
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Brain tumors often result from the unregulated growth of:
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glial cells
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Golgi bodies package ______ and ship them to other parts of the neuron via ______.
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proteins; microtubules.
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Hydrocephalus is usually caused by blockage at:
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the fourth ventricle
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In ______, an allele’s own trait and that of the other allele in the gene pair are expressed
completely. |
codominance
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In the central nervous system there are approximately:
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100 billion neurons
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Membranes of a cell are made of special molecules called:
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phospholipids
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Microglia originate in:
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the blood
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Multiple sclerosis symptoms are caused by:
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loss of myelin on axons.
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Neurons
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have only one axon
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|
Proteins are assembled in:
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the endoplasmic reticulum
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|
Since the mutation that leads to Tay-Sachs disease is recessive, the probability that a child of two
parents who both carry the recessive Tay-Sachs allele will later develop Tay-Sachs disease is: |
25%
|
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The Golgi stain made use of ______ to stain neurons so they could be viewed under a microscope.
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silver nitrate
|
|
The blood-brain barrier is made up of ___ attached to neurons and blood vessels.
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astrocytes
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The cell membrane is important because:
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it controls the amount of water in the cell and regulates the concentration of salts on two sides of the membrane.
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The gene that is most common in a population is called a:
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wild-type gene
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The place where protein packages are wrapped and shipped in a cell is called:
|
golgi body
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The simplest neuron is a(n):
|
bipolar neuron
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Which glial cells operate as part of the brain's immune system?
|
microglia
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Which of the following glial cells are responsible for producing cerebrospinal fluid (CSF)?
|
ependymal cells
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______ are known for having the largest cell bodies and the longest axons.
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motor neurons
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______ is a structure that gathers, stores, and releases energy.
|
the mitochondrion
|
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Heterozygous
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-having two different alleles for the same trait
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Dominant
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-routinely expressed as a trait
|
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cerebrum (forebrain)
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-major structure of the forebrain that consists of two virtually identical hemispheres
-conscious behavior |
|
brainstem
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-central structure of the brain responsible for most unconscious behavior
|
|
cerebellum
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-major structure of brainstem
-specialized for coordinating and learning skilled movements |
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neuron
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-specialized nerve cell engaged in information processing
|
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spinal cord
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-part of CNS
-provides most of the connections between the brain and rest of body |
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CNS
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-brain and spinal cord that together mediate behavior
|
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PNS
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-all the neurons in the body located outside the brain and spinal cord
-provides sensory and motor connections to and from the CNS |
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embodied language
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-hypothesis that the movements we make and the movements we perceive in others are central to communication with others
|
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psyche
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-an entity once proposed to be the source of human behavior
|
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mind
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-proposed nonmaterial entity responsible for intelligence, attention, awareness, and consciousness
|
|
mentalism
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-explanation of behavior as a function of the nonmaterial mind
|
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dualism
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-philosophical position that holds that both a nonmaterial mind and material body contribute to behavior
|
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materialism
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-behavior can be explained as a function of the brain and the rest of the nervous system without explanatory recourse to the mind
|
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species
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-group of organisms that can interbreed
|
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phenotype
|
-individual characteristics that can be seen or measured
|
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genotype
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-particular genetic makeup of an individual
|
|
epigenetics
|
-differences in gene expression related to environment and experience
|
|
Minimally Conscious State (MCS)
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-condition in which a person can display some rudimentary behaviors, such as smiling or uttering a few words, but otherwise is not conscious
|
|
Traumatic Brain Injury (TBI)
|
-wound to the brain that results from a blow to the head
|
|
Persistent Vegetative State (PVS)
|
-condition in which a person is alive but unable to communicate or to function independently at even the most basic level
|
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Clinical trial
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-consensual experiment directed toward developing a treatment
|
|
Deep brain stimulation (DBS)
|
-neurosurgery in which electrodes implanted in the brain stimulate a targeted area with a low-voltage electrical current to facilitate behavior
|
|
Common ancestor
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-fore bearer from which two or more lineages or family groups arise and so is ancestral to both groups
|
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nerve net
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-simple nervous system that has no brain or spinal cord but consists of neurons that receive sensory information and connect directly to other neurons that move muscles
|
|
bilateral symmetry
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-body plan in which organs or parts present on both sides of the body are mirror images in appearance. ex. hands are bilaterally symmetrical whereas the heart is not
|
|
segmentation
|
-division into a number of parts that are similar; refers to the idea that many animals, including vertebrates, are composed of similarly organized body segments
|
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ganglia
|
-collection of nerve cells that function somewhat like a brain
|
|
chordate
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-animal that has both a brain and a spinal cord
|
|
cladogram
|
-phylogenetic tree that branches repeatedly, suggesting a taxonomy of organisms based on the time sequence in which evolutionary branches arise
|
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hominid
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-general term referring to primates that walk upright, including all forms of humans, living and extinct
|
|
Encephalization quotient (EQ)
|
-Jerison's quantitative measure of brain size obtained from the ratio of actual brain size to expected brain size, according to the principle of proper mass, for an animal of a particular body size
|
|
apraxia
|
-difficulty in movements
|
|
aphasia
|
-verbal problems
|
|
radiator hypothesis
|
-idea that selection for improved brain cooling through increased blood circulation in the brains of early hominids enabled the brain to grow larger
|
|
neoteny
|
-process in which maturation is delayed and so an adult retains infant characteristics; ideas derived from the observation that newly evolved species resemble the young of their common ancestors
|
|
species-typical behavior
|
-behavior that is characteristic of all members of a species
|
|
culture
|
-learned behaviors that are passed on from one generation to the next through teaching and experience
|
|
What is the brain's primary function?
|
produce behavior or movement
|
|
stimulation
|
the brain needs stimulation in order to orient and direct the body to produce an appropriate response
|
|
perception
|
subjective experiences of reality
|
|
brain is plastic
|
neural tissue has the capacity to adapt to the world by changing how its functions are organized; connections among neurons in a given functional system are constantly changing in response to experience
|
|
neuroplasticity
|
the nervous system's potential for physical or chemical change that enhances its adaptability to environmental change and its ability to compensate for injury; basis for change in the nervous system
|
|
phenotypic plasticity
|
an individual's capacity to develop into more than one phenotype; an individual's genotype interacts with the environment to elicit a specific phenotype from a large genetic repertoire of possibilities
|
|
somatic nervous system
|
part of the PNS that includes the cranial and spinal nerves to and from the muscles, joints, and skin that produce movement, transmit incoming sensory input, and inform the CNS about the position and movement of body parts
|
|
autonomic nervous system
|
part of the PNS that regulates the functioning of internal organs and glands
|
|
afferent
|
-conducting toward a central nervous system structure
-toward |
|
efferent
|
-conducting away from a central nervous system structure
|
|
meninges
|
-three layers of protective tissue that encase the brain and spinal cord
-dura mater, arachnoid, and pia mater |
|
cerebrospinal fluid (CSF)
|
-clear solution of NaCl that fills the ventricles inside the brain and circulates around the brain and spinal cord beneath the arachnoid layer in the subarachnoid space
|
|
cerebral cortex
|
-thin, heavily folded film of nerve tissue composed of neurons that is the outer layer of the forebrain
-neocortex |
|
temporal lobe
|
-part of the cerebral cortex that functions in connection with hearing, language, and musical abilities
-lies below the lateral fissure -beneath temporal lobe |
|
frontal lobe
|
-"executive" functions
-decision making -lies anterior to the central sulcus |
|
parietal lobe
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-direct movements toward a goal or to perform a task
-posterior to the central sulcus |
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occipital lobe
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-visual processes
-back of the brain |
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stroke
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-sudden appearance of neurological symptoms as a result of severely interrupted blood flow
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gray matter
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-areas of the nervous system composed of cell bodies and capillary blood vessels that function to either collect and modify info or to support this activity
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white matter
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-rich in fat-sheathed neural axons that form the connections between brain cells
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ventricle
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-one of four cavities in brain
-contain CSF -cushions brain |
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corpus callosum
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-band of white matter containing 200 million nerve fibers
-connects 2 hemispheres -provide a route for direct communication between them |
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brainstem
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-central structures of the brain
-hindbrain, midbrain, thalamus, hypothalamus -responsible for most unconscious behavior |
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hindbrain
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-pons, medulla, reticular formation, cerebellum
-coordinate and control most voluntary and involuntary movements |
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reticular formation
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-midbrain area in which nuclei and fiber pathways are mixed
-sleep-wake behavior and behavioral arousal |
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midbrain
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-central part of the brain
-contains neural circuits for hearing and seeing -orients movements |
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tectum
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-roof of midbrain
-sensory processing -visual, auditory and production of orienting movements |
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tegmentum
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-floor of midbrain
-collection of nuclei -movement-related, species-specific, and pain-perception functions |
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orienting movement
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-movement related to sensory inputs
-turning head to see source of sound |
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diencephalon
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-"between brain"
-integrates sensory and motor information on its way to the cerebral cortex |
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basal ganglia
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-subcortical forebrain nuclei that coordinate voluntary movements of the limbs and body
-connected to thalamus and midbrain |
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Parkinson's Disease
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-disorder of motor system
-loss of dopamine -tremors, muscular rigidity, and a reduction in voluntary movement |
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Tourette's syndrome
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-disorder of basal ganglia
-tics, involuntary vocalizations |
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limbic system
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-cingulate cortex, amygdala, hippocampus
-motivated behaviors, memory |
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cranial nerve
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-control sensory and motor functions of the head, neck, and internal organs
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vertebrae
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-bones that form spinal column
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dermatome
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-body segment corresponding to a segment of the spinal cord
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Reasons for animal research
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i. Similar mechanisms of behavior and ease of studying animals
ii. Curiosity about animals iii. Clues to human evolution iv. Can’t experiment on humans (but should we be experimenting on animals?) |
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Santiago Ramon y Cajal
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a pioneer of neuroscience
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The structures of an animal cell
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1. membrane
a. Two layers of fat molecules b. Proteins i. Recognition proteins ii. Receptors iii. Ion channels 2. nucleus 3. mitochondrion 4. ribosomes 5. endoplasmic reticulum |
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receptor proteins
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-"keyhole"
-protein molecule has a groove o Key in a lock o Receptor protein = lock o Neurotransmitter = key o Drugs impersonate as a neurotransmitter o Chemical recognition |
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ion channels
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-way through the semipermeable membrane
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Why we need a blood-brain barrier
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1. virus-infected non-neural cells: targeted for destruction
2. virus-infected cells in nervous system: virus particles remain 3. area postrema: monitors blood chemicals that cannot enter other brain areas |
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ii. How the blood-brain barrier works
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1. endothelial cells of capillaries
2. small uncharged molecules cross freely 3. fat-soluble molecules 4. active transport system 5. Alzheimer’s disease impairs blood-brain barrier 6. Prevents many medications from entering brain |
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active transport system
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a. moves some chemicals from blood to brain
i. glucose ii. amino acids iii. purines, choline, and iron iv. certain vitamins and hormones |
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The nourishment of vertebrate neurons
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i. Dependence on glucose and oxygen
1. due to blood-brain barrier 2. ketones 3. liver: converts carbohydrates, amino acids, and glycerol into glucose ii. Requirement for thiamine (vitamin B1) 1. Deficiency leads to Korsakoff’s syndrome |
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somatosensory cortex
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-
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arcuate nucleus
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-
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paraventricular nucleus
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-
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lateral hypothalamic area
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-
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perifornical area
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-
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multiplier effect
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-environment magnifies early tendencies
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Phenylketonuria (PKU)
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a. Inability to metabolize phenylalanine
b. Brain malformations, mental retardation, irritability c. Modified by low phenylalanine diet d. “Heritable” not equal to “unmodifiable” e. Diet difficult to follow |
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How genes affect behavior
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1. Increasing production of a protein
2. Indirect effects 3. Proteins affected by environmental factors |
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Evolution
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change over generations in frequencies of various genes in a population
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Does evolution mean improvement?
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a. Fitness: number of copies of genes that endure in later generations
b. Current genes evolved because they were fit for previous generations |
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Does evolution benefit individual or species?
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neither, genes
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axon hillock
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-juncture of soma and axon where the action potential begins
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myelin sheath
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-an insulating layer that forms around nerves, including those in the brain and spinal cord. It is made up of protein and fatty substances.
-allow impulses to transmit quickly and efficiently along the nerve cells -Makes it more efficient |
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node of ranvier
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-gap in the insulating sheath (myelin) on the axon of certain neurons that serves to facilitate the rapid conduction of nerve impulses
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presynaptic terminal
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end bulb = axon terminal = synaptic button
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interneuron
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-association neuron interposed between a sensory neuron and a motor neuron
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astrocytes
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a. encircle several presynaptic terminals
b. take up, store and transfer chemicals c. help synchronize activity of axons d. remove waster e. help control blood flow i. increase blood flow to areas experiencing heightened activity |
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microglia
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-remove wastes, viruses, fungi
o Small glial cells o Housekeepers of cells o Clean up dead, dying, diseased tissue o Phagocytes – consume/engulf the dead cells/tissue |
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oligodendrocytes (brain & spinal cord) and Schwann cells (pheriphery)
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a. form myelin sheaths
b. surround and insulate vertebrate axons o Few branches o Makes multiple pieces of myelin o provide support to axons and to produce the Myelin sheath, which insulates axons |
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Radial glia (type of astrocytes)
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-guide migrating neurons, growing axons and dendrites during development
a. following development, most differentiate into neurons |
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motor neuron
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-neuron that carries info form the brain and spinal cord to make muscles contract
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pyramidal cell
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-distinctive interneuron found in the cerebral cortex
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purkinje cell
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-distinctive interneuron found in cerebellum
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Sodium-potassium pump
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Requires energy
Pumps out 3 NA+ Pumps in 2 K+ Which gives an overall negative charge inside |
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Polarization
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towards the poles
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membrane potential
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-away from a membrane potential of zero
-uneven distribution of ions between the inside and outside of the neuron |
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hyperpolarization
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-expanded the difference between the inside and outside
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depolarization
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bring them closer to the middle
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resistance
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farther down the axon the stimulus becomes less
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voltage-gated
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opened because the voltage has changed
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chemical-gated
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open because chemically bonded
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voltage
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ability to do work
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phospholipid bilayer
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o 2 layers
o Lipid=fat o Inside is lipids, so fat o Inside and outside is fluid o Cytoplasm is on the inside (intracellular fluid) o Extracellular fluid is outside • Hydrophilic head • Love water • Attracted to water • Hydrophobic tail • Middle of the cell • “afraid” of water |
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cholesterol
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-stabilizes cell membranes
-use for steroid hormones |
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recognition protein
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-has carbohydrate stuck on end of it
-recognize when it is bumped up against another cell |