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62 Cards in this Set
- Front
- Back
There are three types of
nervous system cells: |
1. Neurons
2. Glia 3. Stem cells |
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Define neuron
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Neurons: information processing
cell |
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Define Glia
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Glia: provide many functions,
including providing nutrients and insulation to neurons |
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Define Stem Cell
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Stem cell: can give rise to any type
of cell in the body |
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______ _____ migrate from the
cell lining of the lateral ventricles and travel to the _______ bulbs |
Stem cells; olfactory
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_____ _____ in the posterior
migrate to the hippocampus |
Stem cells
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How did Reynolds discover stem cells?
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He took cells, put them in a dish with
nerve growth factor = showed cells multiplied and could be turned into different cell types with different growth factors |
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cell body
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houses genetic material; metabolism
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_____ ______ gives rise to axon
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Axon hillock
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_____ takes info away from cell body
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Axon
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define Axon collaterals
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branches off of axon
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define Teleodendria
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“end branches” of the dendrites
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define Terminal buttons
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transmits info to synapse
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define Dendrites
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gathers info and sends to soma
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______ _____: where info is received from
other neurons |
Dendritic spines
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_______: space between spine and end foot
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Synapse
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There are 5 kinds of neurons:
Name them |
1. Pyramidal
2. Stellate 3. Purkinje 4. Motor 5. Dorsal root ganglion |
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_______ _______ are the
output cells of the cortex They have apical branches and basal branches |
Pyramidal neurons
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_______ ______ are located in the
eye and hippocampus |
Stellate cells
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Purkinje cells are only found in
the _______; they are output cells |
cerebellum
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______ ______ are located in
the spinal cord They receive projections from pyramidal cells in the cortex |
Motor neurons
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______ ______ are located in
the spinal cord They receive projections from pyramidal cells in the cortex |
Motor neurons
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______ ______ dendrites are
short and stubby and many of their end feet synapse on muscle |
Motor neuron
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______ ______ dendrites are
short and stubby and many of their end feet synapse on muscle |
Motor neuron
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______ ______ ganglion
cells are sensory cells You have a ganglion for each segment of the spinal cord |
Dorsal root
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______ ______ ganglion
cells are sensory cells You have a ganglion for each segment of the spinal cord |
Dorsal root
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The largest neurons in the
central nervous system are the sensory neurons from the ____ _____. |
big toe
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The largest neurons in the
central nervous system are the sensory neurons from the ____ _____. |
big toe
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There are 5 types of glial cells: what are they?
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1. Ependymal
2. Microglia 3. Astroglia 4. Oligodedroglia 5. Schwann cells |
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There are 5 types of glial cells: what are they?
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1. Ependymal
2. Microglia 3. Astroglia 4. Oligodedroglia 5. Schwann cells |
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_______ cells line the
ventricles and make the cerebral spinal fluid that fill the ventricles |
Ependymal
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_______ migrate into the
brain from the bloodstream and eat dead cells and other matter in the brain |
Microglia
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Astroglia have many functions:
What are some of them? |
1. Connect neurons together
2. Connect neurons to blood vessels 3. Collect nutrients from blood 4. Block bad stuff from getting in the brain (blood brain barrier) |
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__________ wraps itself
around axons of the central nervous system; leaving gaps between cells = myelination |
Oligodendroglia
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_______ cells wrap
themselves around axons of the peripheral nervous system |
Schwann
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What are some diseases of the neurons and glia?
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Diseases of neurons and glia
1. Multiple sclerosis (MS) 2. Polio 3. Amyotrophic lateral sclerosis (ALS) 4. Myasthenia gravis |
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describe multiple sclerosis
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Multiple sclerosis is a disease
of the oligodendroglia these cells begin to die, and information gets lost between the brain and spinal cord (both motor and sensory) |
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describe Polio
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Polio is an attack of motor
neurons As neurons are lost, muscles loose input and begin to shrivel up |
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describe Amyotrophic lateral sclerosis
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Amyotrophic lateral sclerosis
has an unknown cause, but attacks motor neurons gradual process |
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describe Myasthenia gravis
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Myasthenia gravis is a result of an
impairment to axon end feet People wake up feeling fine, and by the end of the day, are exhausted Was called “tired housewife syndrome” |
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The structure of the cell is a
________ The function is to channel, gate, pump, and transmit |
factory
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Cell has three features- what are they?
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• 1. Membrane: maintains integrity of the
cell • 2. Outside of the membrane is a fluid called extracellular fluid • 3. Inside of the membrane is a fluid called the intracellular fluid |
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Inside the cell is a number of
structures: what are they? (there's 5) |
1. Nucleus
2. Endoplasmic reticulum 3. Golgi bodies 4. Microtubules 5. mitochondria |
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The _______ of the a contains DNA and DNA codes for proteins
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nucleus
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There are a series of steps to get from DNA to protein- go through them
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DNA gets transcribed to RNA
• RNA goes to endoplasmic reticulum where the RNA gets translated into a protein • Protein goes to the golgi bodies where it is packaged into a vesicle • Microtubule carries vesicle to location in cell |
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3 possible things can happen to a protein once it reaches the end foot of a neuron:
1) it can be ______ 2) it can be incorporated into the _______ 3) it can be excreted into the ____ |
1) stored
2) membrane 3) synapse |
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Cell membrane:
-is made up of ______ molecules -_____ is a phosphor group with a charge -_____ is lipid (fat) with no charge |
phospholipid; Head; Tail
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In a cell membrane, _____ likes water (hydrophilic)
____ hates water (hydrophobic) Arranged in a bilayer with heads pointing out and tails pointing in |
Head; Tail
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Bilayer membrane prevents
_____ from entering or exiting It also lets some small molecules in and out of the cell |
water
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The nucleus of a cell contains _______: humans have 23 pairs (half from mom and half from dad)
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chromosomes
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The first ____ chromosomes are
called autosomes The 23rd chromosome is the _____ chromosome |
22; sex
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We have 20 to 25 ________
genes and 3 billion base pairs One gene = ____ protein |
thousand; one
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We should have one protein
for every gene, but we have more _____ than ____ |
proteins; genes
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Proteins can be cut up, or bind
with other proteins to make an endless number of _______ |
proteins
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Proteins are made up of what?
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amino acids
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Amino acids can take on 4 different kinds of shapes- what are they?
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Primary: sequence of amino acids
-Secondary: plated sheet or helix -Teritary: -Quaternary: combining with other proteins |
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The ____ ____ wraps membrane around protein (vesicle)
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Golgi Body
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What function do microtbules have in the cell?
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-ships vesicle to location in cell
-Vesicle must have a label to tell microtubule where to go -Kinesin moves the vesicles and other materials down the microtubule |
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Proteins that do not like _____ hang out inside the cell
Those that like ____ stick out of the membrane |
water
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Proteins all have jobs to do
with the cell 1. Make ______: allow certain items in and out of the cell (example: sodium) 2. Make _____: change shape under certain conditions to let things in or out 3. Makes _____: actively brings things across the membrane 4. ______: leave cell to do things to other cells |
1) channels
2) gates 3) pumps 4) Messengers |
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Channels are ______; only
let certain types of ions in |
selective
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Nissl stain attaches to
________ to indicate cell bodies. Fluorescent molecules like fatty molecules - so when it gets incorporated, it goes all over the cell |
ribosomes
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