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62 Cards in this Set

  • Front
  • Back
There are three types of
nervous system cells:
1. Neurons
2. Glia
3. Stem cells
Define neuron
Neurons: information processing
cell
Define Glia
Glia: provide many functions,
including providing nutrients and
insulation to neurons
Define Stem Cell
Stem cell: can give rise to any type
of cell in the body
______ _____ migrate from the
cell lining of the lateral
ventricles and travel to the
_______ bulbs
Stem cells; olfactory
_____ _____ in the posterior
migrate to the hippocampus
Stem cells
How did Reynolds discover stem cells?
He took cells, put them in a dish with
nerve growth factor
= showed cells multiplied and could be turned into different cell types with different growth factors
cell body
houses genetic material; metabolism
_____ ______ gives rise to axon
Axon hillock
_____ takes info away from cell body
Axon
define Axon collaterals
branches off of axon
define Teleodendria
“end branches” of the dendrites
define Terminal buttons
transmits info to synapse
define Dendrites
gathers info and sends to soma
______ _____: where info is received from
other neurons
Dendritic spines
_______: space between spine and end foot
Synapse
There are 5 kinds of neurons:
Name them
1. Pyramidal
2. Stellate
3. Purkinje
4. Motor
5. Dorsal root ganglion
_______ _______ are the
output cells of the cortex
They have apical branches
and basal branches
Pyramidal neurons
_______ ______ are located in the
eye and hippocampus
Stellate cells
Purkinje cells are only found in
the _______; they are
output cells
cerebellum
______ ______ are located in
the spinal cord
They receive projections from
pyramidal cells in the cortex
Motor neurons
______ ______ are located in
the spinal cord
They receive projections from
pyramidal cells in the cortex
Motor neurons
______ ______ dendrites are
short and stubby and many of
their end feet synapse on
muscle
Motor neuron
______ ______ dendrites are
short and stubby and many of
their end feet synapse on
muscle
Motor neuron
______ ______ ganglion
cells are sensory
cells
You have a ganglion
for each segment of
the spinal cord
Dorsal root
______ ______ ganglion
cells are sensory
cells
You have a ganglion
for each segment of
the spinal cord
Dorsal root
The largest neurons in the
central nervous system are
the sensory neurons from the
____ _____.
big toe
The largest neurons in the
central nervous system are
the sensory neurons from the
____ _____.
big toe
There are 5 types of glial cells: what are they?
1. Ependymal
2. Microglia
3. Astroglia
4. Oligodedroglia
5. Schwann cells
There are 5 types of glial cells: what are they?
1. Ependymal
2. Microglia
3. Astroglia
4. Oligodedroglia
5. Schwann cells
_______ cells line the
ventricles and make the
cerebral spinal fluid that fill the
ventricles
Ependymal
_______ migrate into the
brain from the bloodstream
and eat dead cells and other
matter in the brain
Microglia
Astroglia have many functions:
What are some of them?
1. Connect neurons together
2. Connect neurons to blood
vessels
3. Collect nutrients from blood
4. Block bad stuff from getting in
the brain (blood brain barrier)
__________ wraps itself
around axons of the central
nervous system; leaving gaps
between cells
= myelination
Oligodendroglia
_______ cells wrap
themselves around axons of
the peripheral nervous system
Schwann
What are some diseases of the neurons and glia?
Diseases of neurons and glia
1. Multiple sclerosis (MS)
2. Polio
3. Amyotrophic lateral sclerosis (ALS)
4. Myasthenia gravis
describe multiple sclerosis
Multiple sclerosis is a disease
of the oligodendroglia
these cells begin to die, and
information gets lost between
the brain and spinal cord (both
motor and sensory)
describe Polio
Polio is an attack of motor
neurons
As neurons are lost, muscles
loose input and begin to
shrivel up
describe Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis
has an unknown cause, but
attacks motor neurons
gradual process
describe Myasthenia gravis
Myasthenia gravis is a result of an
impairment to axon end feet
People wake up feeling fine, and by
the end of the day, are exhausted
Was called “tired housewife
syndrome”
The structure of the cell is a
________
The function is to channel,
gate, pump, and transmit
factory
Cell has three features- what are they?
• 1. Membrane: maintains integrity of the
cell
• 2. Outside of the membrane is a fluid
called extracellular fluid
• 3. Inside of the membrane is a fluid
called the intracellular fluid
Inside the cell is a number of
structures: what are they? (there's 5)
1. Nucleus
2. Endoplasmic reticulum
3. Golgi bodies
4. Microtubules
5. mitochondria
The _______ of the a contains DNA and DNA codes for proteins
nucleus
There are a series of steps to get from DNA to protein- go through them
DNA gets transcribed to RNA
• RNA goes to endoplasmic reticulum
where the RNA gets translated into a
protein
• Protein goes to the golgi bodies where it
is packaged into a vesicle
• Microtubule carries vesicle to location in
cell
3 possible things can happen to a protein once it reaches the end foot of a neuron:
1) it can be ______
2) it can be incorporated into the _______
3) it can be excreted into the ____
1) stored
2) membrane
3) synapse
Cell membrane:
-is made up of ______ molecules
-_____ is a phosphor group with a charge
-_____ is lipid (fat) with no charge
phospholipid; Head; Tail
In a cell membrane, _____ likes water (hydrophilic)
____ hates water (hydrophobic)
Arranged in a bilayer with
heads pointing out and tails
pointing in
Head; Tail
Bilayer membrane prevents
_____ from entering or exiting
It also lets some small
molecules in and out of the
cell
water
The nucleus of a cell contains _______: humans have 23 pairs (half from mom and half from dad)
chromosomes
The first ____ chromosomes are
called autosomes
The 23rd chromosome is the
_____ chromosome
22; sex
We have 20 to 25 ________
genes and 3 billion base pairs
One gene = ____ protein
thousand; one
We should have one protein
for every gene, but we have
more _____ than ____
proteins; genes
Proteins can be cut up, or bind
with other proteins to make an
endless number of _______
proteins
Proteins are made up of what?
amino acids
Amino acids can take on 4 different kinds of shapes- what are they?
Primary: sequence of amino acids
-Secondary: plated sheet or helix
-Teritary:
-Quaternary: combining with other proteins
The ____ ____ wraps membrane around protein (vesicle)
Golgi Body
What function do microtbules have in the cell?
-ships vesicle to location in cell
-Vesicle must have a label to tell microtubule
where to go
-Kinesin moves the vesicles and other
materials down the microtubule
Proteins that do not like _____ hang out inside the cell
Those that like ____ stick out
of the membrane
water
Proteins all have jobs to do
with the cell
1. Make ______: allow certain items in and
out of the cell (example: sodium)
2. Make _____: change shape under certain
conditions to let things in or out
3. Makes _____: actively brings things
across the membrane
4. ______: leave cell to do things to
other cells
1) channels
2) gates
3) pumps
4) Messengers
Channels are ______; only
let certain types of ions in
selective
Nissl stain attaches to
________ to indicate cell
bodies.
Fluorescent molecules like
fatty molecules - so when it
gets incorporated, it goes all
over the cell
ribosomes