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42 Cards in this Set
- Front
- Back
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Bordetella ssp. General Characteristics
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Gram negative coccobacillus
capsule motile with flagella |
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Bordetella ssp ALET
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aerobic bacteria
extracellular bacteria Natural habitat UR |
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Bordetella ssp.
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B. Bronchiseptica (cats, dogs, pigs and rabbits
B. avium (birds) B pertussus (humans) |
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Bordetella bronchiseptica characteristics
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Canine infectious trachebronchitis, Can be primary but usually complex
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B. bronchiseptica complex
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viral component
stress component B. bronchiseptica component Mycoplasma |
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B. bronchiseptica virulence in cats is
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similar to dogs
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B. bronchiseptica transmission
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inhalation contact with sick animals, sputum, water bowl, fomites
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B. bronchiseptica natural environment
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Natural flora, will usually culture from all animals, stress changes internal environment
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B. bronchiseptica adherence
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fimbria, tracheal colonization factor (exo), filamentous haemagglutinin, LPS (endo) - to ciliated epithelial cells
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B. bronchiseptica virulence
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Capsule - LPS - protects against phagocytosis via neutrophils and macrophages
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Bordetella spp. exotoxins
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a dermonecrotic toxin
tracheal cytotoxin |
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Bordetella spp pathogenesis
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increased mucus, and fluid in UR, destruction of ciliated epith., depressed respiratory clearance mechanisms, reduced ability to remove or kill organisms
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B. bronchiseptica, + P. multocida =
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atrophic rhinitis
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Atrophic rhinitis pathogenesis
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B bronch. inital infection, P multocida joins and is osteolytic causing atrophy of nasal turbinates in pigs
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Atrophic rhinitis is harmful because
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it removes filtration before lungs
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B. bronchiseptica without P. multocida results in
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reversible turbinate hypoplasia
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B. avium
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Turkey coryza
direct contact, aerosolization, fomites, nasal exudate, conjunctivitis, trachael rales, dyspnea |
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Prevention of Bordetella
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isolate animals with clinical signs, reduce predisposing/associated factors
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B. pertussis virulence factors
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same as other Bordetella with pertussis toxin
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Bordetella zoonosis
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NONE
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Bordetella capsule protects the bacteria by
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inhibiting phagocytosis and attachment of the outer membrane attack complexes of complement
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Pseudomonas spp General Characteristics
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Gram negative bacillus, non-spore forming, flagella
pili |
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Pseuduomonas spp. ALET
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obligate aerobe
soil, water, feces, ubiquitous |
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Pseudomonas spp. Virulence factors
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pili
capsular polysaccaride LPS Protease Elastase Biofilm |
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Pseudomonas spp. pathogenesis
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opportunistic pathogen, rarely infects uncompromised tissue, resistant to antimicrobials, disrupts normal flora, breaches host defenses
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Pseudomonas spp exotoxins
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proteases
elastases |
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Pseudomonas aeruginosa typical contaminate locations
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multidose mastitis treatments, instruments, hydorthearpy baths, semen extenders, liquid hand soaps - opportunistic pathogen
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Pseudomonas aeruginosa diseases
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mastitis, corneal ulcers, otitis externa, fleece rot,
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Pseudomonas predisposing factors
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wet, high humidity, disruption of skin integrity,
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What bacteria causes similar disease to Pseudomonas?
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Dermatophilus
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Disease process of pseudomonas aeruginosa
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breach defenses
adherence exotoxin endotoxin proteases |
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Pseudomonas prevention, control and zoonosis
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Hygiene
Zoonotic but opportunistic |
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Burkholderia spp. general characteristics
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Gram negative bacillus
non-spore forming non-motile |
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Burkholderia ALET
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aerobic
facultative intracellular Natural habitat- soil (most) |
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Burkholderia ssp
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Burkholderia mallei - glanders in equine
Burkholderia pseudomallei - maliodiosis - zoonotic |
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Burkholderia mallei
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reservoir - infected equidae
survives , 2 weeks in the set moist, dark environment |
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Burkholderia mallei - acute symptoms
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fever, catarrhal nasal discharge respiratory, cutaneous, and lymphatic, nodular lesions, lymphadenitis of head and neck - death in 2 weeks
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Burkholderia mallei - chronic symptoms
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same as acute + mestastatic lesions in lungs and other organs - survive several years and infective
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Burkholderia mallei transmission
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highly contagious
ingestion common route, feed bunks, buckets, watering troughs, and buckets, |
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Burkholderia mallei virulence factors
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toxins,
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Burkholderia pseudomallei
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fatal disease of humans, and other mammals, fever, maylgia, pneumonia, sepsis, abscess at point of infection but spreading everywhere, ingestion, inhalation, contact
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Burkholderia spp. culture
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blood and tissue
reportable cull infected animals |
