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24 Cards in this Set

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What are the main causes of pulmonary edema?
increased hydrostatic pressure

left heart failure, mitral stenosis, Pulmonary vein obstruction

decreased oncotic pressure

lymphatic obstruction

microvascular injury - infection, toxins, shock, radiation
What causes the different types of pneumonia:
Bronchopneumonia
lobar pneumonia (classic)
atypical pneumonia
Legionnaire's disease
B - Haemophilus, Pseudomonas

LP - Pneumococcus, Klebsiella

A - viral, Mycoplasma (young adults, college)

LD - Legionella (elderly via water reserves)
What are the non-smoking related lung tumors?
benign - adenoma, leiomyoma, hamartoma

carcinoid - potentially malignant, carcinoid syndrome suggests widespread metastasis

adeno CA - peripheral, weakly related to smoking
What are the smoking related lung tumors?
squamous CA - central, strong correlation with smoking, paraneoplastic: PTH like peptide

small cell CA - central, hormone producing, aggressive, paraneoplastic: ACTH, ADH

large cell CA - peripheral, poorly differentiated adeno or squamous CA
What is the difference in nephrotic and nephritic syndromes
nephrotic - severe prteinuria, hpoalbuminemia, hyperlipidemia, edema
adults: membranous GN
children: minimal change GN

nephritic: hematuria, RBC casts
post strep GN
What are the good prognosis GN? Poor prognosis?
good - minimal change (childrean - loss of foot processes), diffuse proliferative (subepithelial deposits)

poor - membranous (young adults - thickened GBM), membrano-proliferative (tram track), focal segmental (IgM deposits), rapidly progressive (crescents)
What is the most common cause for kidney stones?
Calcium - precipitates alkaline urine - tx: thiazide, K phosphate

others:
Mg-NH3-phosphate - staghorn calculi
uric acid - gout
cystine - congenital defect
Causes of vernereal diseases:
trichomoniasis
gonorrhea
non-gonococcal urethritis
lyymphogranuloma venereum
granuloma inguinale
chancroid
syphillis 1,2,3
condyloma acuminatum
herpes
T - trichomonas vaginalis
G - Neisseria gonorrhoeae
Non - Chlamydia trachomatis
L - Chlamydia trachomatis
Gran - C. Donofani
Chan - Hemophilus ducreyi
S - Trepnema Pallidum
Condy - HPV
herp - HSV2 or 1
Which scrotal masses are malignant? Benign?
M- testicular masses

B - extra-testicular
What is the difference between serous and mucinous ovarian tumors?
both are surface epithelial tumors with cysts.
serous has ciliated epithelium
mucinous has non ciliated epithelium.
What are the types of endometrial proliferation?
polyps - excessive bleeding, rarely malignant

hyperplasia - excessive bleeding, premalignant

carcinoma - adenocarcinoma, asymptomatic or bleeding
Coomplete vs Partial Hydatidiform mole
C - no embryo or placenta, 46 XX of paternal origin

P - embryo and placenta are present, triploid or tetraploid karyotype
what is the difference between fibrocystic breast change and breast cancer?
Fibro - often bilateral, multiple nodules, menstrual variation, regress during preggers

cancer - often unilateral, single mass, no cyclic variations
What does Vit c deficiency cause? Vit B2? Bit B12?
C - bleeding gums

B2 - glossitis, cheilosis

B12 - smooth beefy red tongue
difference between Pulsion (Zenker) Diveticula and Traction Diverticula?
Z - false (mucosa only), at junction of pharynx/esophagus, dysphagia, regurge

T - true (all layers), mid part of esophagus, asymptomatic
What is the difference between Type A and B chronic Gastritis
A - fundal - autoimmune, pernicious anemia, achlorhydria

B - antral - H. pylori
What are the genetic pedigrees for colon polyposis:
familial adenomatous
gardner's
turcot's peutz-jeghers
F - AD

G - AD

T - AR

PJ - AD
Crohn's vs Ulcerative Colitis
C - rectum often spared, ileum often involved

skip lesions, transmural

granulomas, strictures and fissures

more pain, less bleeding
UC - begins at rectum and progresses toward ileocecal junction

continuous, mucosa/submucosa only

crypt abscesses, pseudopolyps

more bleeding, less pain

increased risk of colon cancer, toxic megacolon
Difference between GB and Bile Duct cancers?
GB - female, cholelithiasis, porcelain GB (calcium deposits in wall, high risk of malignancy)

BD - male, chronic infections, liver fluke (clonorchis sinesis)
What are the types of jaundice?
prehaptic - hemolysis - unconjugated bilirubin

hepatic - hapatitis - con/unconjugated

posthepatic - cholestasis - cojugated
Which types of Hepatitis are fecal/oral route? Parenteral?
FO - Hep A/E

P - Hep B/C/Delta
What do the Hep B markers indicate?
HBeAg - infection

HBsAg - early marker/ carrier

anti-HBsAg - recovery/immunity

anti-HBcAg - window period
Difference between the types of liver cancer:
metastatic
hepatocellular
cholangiocarcinoma
M - most common - from breast, lung, colon

H - 90% of primary cancers - HBV and HCV aflatoin, increased AFP

C - 10% of primary cancers - common in Asia due to liver flukes
Difference between osteoarthritis and rhuematoid arthritis
OA - women>men

loss of cartilage
narrow joint space
increased density of subchondral bone
osteophyte formation

knees, hips, spine
distal interphalangeal joints

joints stiffness after inactivity

heberden's nodes
RA - women 20-50

synovial membrane proliferation (pannus)
erosions of cartilage and subchondral bone

starts in small joints
proximal interphalangeal joints
metacarpophalangeal joints

morning stiffness
soft tissue swelling
rheumatoid nodules

rheumatoid factor: anti IgG