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12 Cards in this Set
- Front
- Back
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What effect does LSD have on the brain?
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acts on serotonergic receptors, acting as a serotonin agonist in the midbrain
activates the sympathetic nervous system to cuse arousal, tachycardia, sweating, mydriasis, high BP, piloerection, and fever |
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What is the medical use of ketamine?
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anesthetic
also the anesthetic of choice for trauma victims because of its effects on raising BP |
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What are the actions of Mu/Kappa receptor stimulation?
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Mu - resp depression, euphoria/sedation, physical dependence, decreased GI motility, pupil constriction, ANALGESIA
Kappa - analgesia, sedation/dysphoria, pupil constriction |
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What is the use of naloxone?
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displaces all receptor-bound opiate molecules
reverses overdose of opiates |
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How do TCAs help severe major depressive disorder?
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block reuptake of NE and serotonin, increasing the neurologic response.
Elevates mood, improves alertness, increases physical activity, and reduces morbid preoccupation |
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What are SSRIs used for?
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block re-uptake of serotonin
indications are depression, bulimia nervosa, OCD, anorexia nervosa, panic disorder, diabetes-related neuropathic pain, and PMS |
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What drug can be used for smoking cessation?
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Bupropion
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What is the major SE of lamotrigine?
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severe, potentially life-threatening rashes like SJS and toxic epidermal necrolysis
inhibit voltage-gated Na channels. Prolongs relative refractory period. Mediates its anti-seizure effects. |
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WHat is carbamazepine used for?
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bipolar disorder, seizure disorder, phantom limb syndrome and ADD/ADHD.
DOC for trigeminal neuralgia |
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What are the effects of caffeine at low doses? high doses?
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low - increases alertness by stimulating the cortex and other brain areas
high - anxiety, tremors, positive inotropy and chronotropy |
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What is cocaine's medical use?
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psychomotor stimulant
local anesthesia for ear, eye, nose and throat |
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What are amphetamines MOA?
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release intracellular stores of catecholamines as well as blocking MAO; they are adept at releasing high quantities of dopamine
used in depression, hyperactive children, appetite control, and narcolepsy |
