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8 Cards in this Set
- Front
- Back
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What is Prazosin used for?
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alpha-1 blockers
used for HPTN, also used for BPH (decreasing tone of the prostatic urethral smooth muscle 1st does syncope is SE |
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What are beta blockers used for?
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migraine prophylaxis - decreases VD in CNS.
glaucoma - block ciliary body secretion of aqueous humor - decreasing pressure can't be used in pts with bronchoconstrictive problems because it causes constriction |
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What is the antidote for Organophosphate (nerve gas/insecticide) overdose?
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atropine or pralidoxime (2-PAM)
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What is bethanechol used for? Pilocarpine? Carbachol?
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direct cholinergic drugs - stimulate parasymp
B - atonic bladder - especially postpartum - increases tonicity P - acute angle glaucoma - causes miosis, allowing for better drainage of aqueous humor - most potent stim of glandular secretion C - glaucoma - similarly to pilocarpine - long duration w high potency |
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What is atropine used for? Scopolamine?
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anti-muscarinics
A - centrally and peripherally on muscarinics - reversal of bradycardia and reduction of hyperactive bladder (gotta go). Cycloplegia S - motion sickness, blocks short term memory |
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What is succinylcholine used for?
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anti-nicotinic
acts like ACh - binding at ACh receptor - causing initial fasciculations due to stim. Then, flaccid paralysis occurs. primary uses are for rapid endotracheal intubation, electro shock therapy, surgery can cause significant apnea risk of malignant hypothermia especially if w halothane |
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What are the roles of adrenergic receptors?
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Beta - stim adenylate cyclase, yielding high cAMP
Alpha 1 - stimulate PLC, yielding high DAG, IP3; resulting in activated protein kinase C and high calcium Alpha 2 - inhibits adenylate cyclase, yielding low cAMP |
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What is progesterone used for?
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maintain the endometrium, inhibiting gonadotropin release. Normally, produced in response to LH.
major use for contraception and endometriosis can also be used for endometrial Ca, treat dysmenorrhea, and to control dysfunctional uterine bleeding. Used after conception to prevent further fetal loss in women who have habitual abortion |
